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Mostrando 1-11 de 11 artigos, teses e dissertações.
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1. Sensibilité, coquetterie et libertinage / Sensibilidade, coquetismo e libertinagem: a Pamela inglesa, as Pamelas francesas e as mudanças éticas e estéticas no século XVIII
La thèse examine la réception de Pamela; or Virtue rewarded, de Richardson, dans la France du XVIIIè siècle. Le roman de 1740 est analysé à partir de ses ambiguïtés constitutives: lérotique et la individuel-subjective. Au commencement, il est comparé aux prédécesseurs français influents: Lettres portugaises, atribué à Guillerages (1669), et La
Publicado em: 2007
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2. Étude de l application des revêtements routiers à chaud très minces au Brésil. / Estudo da utilização de revestimentos asfálticos delgados a quente para pavimentos tipo BBTM no Brasil.
A tese apresenta o estudo de revestimentos asfálticos delgados a quente para pavimentos rodoviários do tipo BBTM, nas graduações 0/6 e 0/10, com diâmetro nominal máximo de 6 mm e 10 mm, respectivamente. Este estudo introduz uma nova tecnologia de restauração de pavimentos no Brasil e identifica as possíveis adaptações para a execução, aplicaçã
Publicado em: 2006
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3. Temporal production of streptococcal erythrogenic toxin B (streptococcal cysteine proteinase) in response to nutrient depletion.
The effects of various growth conditions on the production of streptococcal erythrogenic toxin B (streptococcal pyrogenic exotoxin B [SPE B]) by Streptococcus pyogenes were analyzed. SPE B was detected in broth culture supernatant fluid only during the stationary phase of growth when glucose and other potential carbon sources were depleted from the medium. A
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4. Formation of Single-Stranded DNA during DNA Transformation of Neisseria gonorrhoeae
Neisseria gonorrhoeae is naturally competent for DNA transformation. In contrast to other natural prokaryotic DNA transformation systems, single-stranded donor DNA (ssDNA) has not previously been detected during transformation of N. gonorrhoeae. We have reassessed the physical nature of gonococcal transforming DNA by using a sensitive nondenaturing native bl
American Society for Microbiology.
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5. The rgg Gene of Streptococcus pyogenes NZ131 Positively Influences Extracellular SPE B Production
Streptococcus pyogenes produces several extracellular proteins, including streptococcal erythrogenic toxin B (SPE B), also known as streptococcal pyrogenic exotoxin B and streptococcal proteinase. Several reports suggest that SPE B contributes to the virulence associated with S. pyogenes; however, little is known about its regulation. Nucleotide sequence dat
American Society for Microbiology.
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6. Streptococcal Erythrogenic Toxin B Abrogates Fibronectin-Dependent Internalization of Streptococcus pyogenes by Cultured Mammalian Cells
Streptococcus pyogenes secretes several proteins that influence host-pathogen interactions. A tissue-culture model was used to study the influence of the secreted cysteine protease streptococcal erythrogenic toxin B (SPE B) on the interaction between S. pyogenes strain NZ131 (serotype M49) and mammalian cells. Inactivation of the speB gene enhanced fibronect
American Society for Microbiology.
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7. Rgg Influences the Expression of Multiple Regulatory Loci To Coregulate Virulence Factor Expression in Streptococcus pyogenes
The human pathogen Streptococcus pyogenes secretes many proteins to the cell wall and extracellular environment that contribute to virulence. Rgg regulates the expression of several exoproteins including a cysteine protease (SPE B), a nuclease (MF-1), a putative nuclease (MF-3), and autolysin. The functional heterogeneity of Rgg-regulated exoproteins and the
American Society for Microbiology.
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8. Rgg Coordinates Virulence Factor Synthesis and Metabolism in Streptococcus pyogenes
Streptococcus pyogenes is a human-specific pathogen that relies on its host for metabolic substrates. Rgg-like proteins constitute a family of transcriptional regulators present in several gram-positive bacteria. In S. pyogenes, Rgg influences the expression of several virulence-associated proteins localized to the cell wall and extracellular environment. Se
American Society for Microbiology.
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9. Rgg Regulates Growth Phase-Dependent Expression of Proteins Associated with Secondary Metabolism and Stress in Streptococcus pyogenes
The transcriptional regulatory protein Rgg coordinates amino acid catabolism and virulence factor expression in Streptococcus pyogenes. We used a proteomic approach to compare cytoplasmic proteins isolated from S. pyogenes wild-type strain NZ131 (serotype M49) to proteins isolated from an rgg mutant strain during the exponential and stationary phases of grow
American Society for Microbiology.
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10. Identification of Rgg-Regulated Exoproteins of Streptococcus pyogenes
Streptococcus pyogenes secretes many proteins that influence host-pathogen interactions. Despite their importance, relatively little is known about the regulation of these proteins. The rgg gene (also known as ropB) is required for the expression of streptococcal erythrogenic toxin B (SPE B), an extracellular cysteine protease that contributes to virulence.
American Society for Microbiology.
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11. Inactivation of the streptococcal erythrogenic toxin B gene (speB) in Streptococcus pyogenes.
Streptococcal proteinase precursor (SPP) is a zymogen secreted by Streptococcus pyogenes that becomes activated to a cysteine proteinase. SPP has been shown to be immunologically identical to streptococcal erythrogenic toxin B (SPE B), and sequence comparison has shown a high degree of homology between the two proteins. In this study, we have constructed a s