Chelators
Mostrando 1-12 de 295 artigos, teses e dissertações.
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1. Treatment of iron overload syndrome: a general review
RESUMO INTRODUÇÃO A síndrome de sobrecarga de ferro engloba um grande espectro de etiologias que levam a um aumento da quantidade de ferro nos tecidos. Esse ferro excede a capacidade de proteção dos tecidos, levando a dano oxidativo e lesão tissular. Tratamento pode prevenir esse dano, levando à melhor sobrevida. METODOLOGIA A literatura dos últi
Rev. Assoc. Med. Bras.. Publicado em: 10/10/2019
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2. Modulatory effect of iron chelators on adenosine deaminase activity and gene expression in Trichomonas vaginalis
Trichomonas vaginalis is a flagellate protozoan that parasitises the urogenital human tract and causes trichomoniasis. During the infection, the acquisition of nutrients, such as iron and purine and pyrimidine nucleosides, is essential for the survival of the parasite. The enzymes for purinergic signalling, including adenosine deaminase (ADA), which degrades
Mem. Inst. Oswaldo Cruz. Publicado em: 23/10/2015
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3. Cloning and Functional Assessment of the Recombinant Human Hepcidin-25 in the Baculovirus Expression System
Hepcidin is the primary regulatory hormone responsible for lowering the iron content in the blood circulation. Due to its biodegradability and low cytotoxicity, hepcidin is considered as an alternative for iron chelators. The baculovirus expression system may be suitable for human hepcidin production because the expressed proteins generally exhibit proper fo
Braz. arch. biol. technol.. Publicado em: 01/08/2014
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4. VINHO TINTO, SUCO DE UVA E ETANOL EM RATOS ADULTOS SUBMETIDOS À DIETA HIPERLIPIDÊMICA
Special attention has been focused on protection against diseases associated with oxidative stress such as cancers, diabetes, cardiovascular diseases, aging and neurodegenerative disease in the last years. Previous reports indicate that highcholesterol diets induced oxidative stress and hypercholesterolemia in rats. Some dietary compounds such as polyphenols
Publicado em: 2009
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5. Interações de peroxirredoxinas citossólicas da levedura Saccharomyces cerevisiae com peróxidos. Estudos cinéticos e funcionais / Saccharomyces cerevisiae cytosolic peroxiredoxin interactions with peroxides. Kinetics and functional studies
Peroxiredoxins constitute a family of cysteine-based peroxidases that are able to reduce hydrogen peroxide, organic peroxides and peroxinitrite to water, alcohol and nitrite, respectively, through the use of reducing equivalents provided by thioredoxin, thioredoxin reductase and NADPH. Peroxiredoxins are abundant enzymes (correspond to approximately 0.7% of
Publicado em: 2009
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6. CO-SITE DIGITAL MICROSCOPY AND ATOMIC ABSORPTION SPECTROSCOPY IN THE ANALYSIS OF THE CHELATING EFFECT ON HUMAN DENTINE / MICROSCOPIA DIGITAL CO-LOCALIZADA E ESPECTROSCOPIA DE ABSORÇÃO ATÔMICA NA ANÁLISE DO EFEITO QUELANTE SOBRE A DENTINA HUMANA
A partir dos anos 70 constatou-se a formação de uma massa aderida às paredes do canal radicular, após a instrumentação, que foi denominada smear layer. Esta camada é composta de material orgânico e inorgânico, tecido pulpar e bactérias, e contribui para obliterar os túbulos dentinários. A remoção desta camada melhora a adaptação entre o mater
Publicado em: 2008
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7. APLICAÇÃO DA MICROSCOPIA DIGITAL NA QUANTIFICAÇÃO DO EFEITO DE QUELANTES EM DENTINA / DIGITAL MICROSCOPY APPLIED TO THE QUANTIFICATION OF THE EFFECT OF CHELATORS ON DENTINE
Instrumentation methods currently used in endodontic therapy create a residual layer composed of organic and inorganic material. There is no universal consensus regarding the ideal method for removing this smear layer and exposing the dentinary tubules, necessary for the adaptation of root canal filling. In general, chelating solutions are used but the ideal
Publicado em: 2006
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8. IgG purification from human plasma by membrane affinity chromatography with immobilized Cu(II) and Ni(II) : effect of quelators IDA, TREN and CM-Asp / Purificação de IgG a partir do plasma humano por cromatografia em membranas con ions Cu(II) e Ni(II) imobilizados : efeito dos agentes quelantes IDA, TREN e CM-Asp
The use of immunoglobulin G (lgG) in therapeutic applications has growing vastly and it is used in the treatment of a growing number of indications. Several chromatographic techniques have been investigated for IgG purification. In this work, we investigated the effect of the chelators iminodiacetic acid (IDA), carboxymethylaspartate acid (CM-Asp) and Tris-2
Publicado em: 2006
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9. STUDY OF SULFHYDRYL CHELATORS (BAL, DMPS AND DMSA): EFFECTS ON TOXICOLOGICAL PARAMETERS AND MODELS OF CADMIUM INTOXICATION / ESTUDO DOS QUELANTES SULFIDRÍLICOS (BAL, DMPS E DMSA): EFEITOS SOBRE PARÂMETROS TOXICOLÓGICOS E MODELOS DE INTOXICAÇÃO POR CÁDMIO
Diversos metais alteram as funções celulares por serem capazes de se ligar a grupos tióis de biomoléculas. Portanto, uma terapia eficaz na intoxicação por metal seria a remoção dos metais tóxicos dos bioligantes funcionais através da administração de quelantes contendo grupos tióis. Entretanto, estes compostos poderiam remover metais endógenos,
Publicado em: 2005
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10. MICROSCOPIA DE FORÇA ATÔMICA IN SITU E MICRODUREZA DE DENTINA SUBMETIDA A SUBSTÂNCIAS QUELANTES / IN SITU ATOMIC FORCE MICROSCOPY AND MICROHARDENESS OF DENTIN THROUGHOUT THE CHELATION PROCESS
Instrumentation methods currently used in endodontic therapy create a residual layer composed of organic and inorganic material that frequently retains bacteria and their subproducts. The available methods to remove this smear layer include chemical etching, ultrasonic and laser techniques but none of these is completely efficient and there is no universal c
Publicado em: 2004
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11. Identifying sugarcane expressed sequences associated with nutrient transporters and peptide metal chelators
A absorção de nutrientes pelas plantas é um processo ativo, requerendo energia para o acúmulo de nutrientes essenciais em níveis mais elevados nos tecidos vegetais do que na solução do solo, enquanto que a presença de metais tóxicos ou excesso de nutrientes requererem mecanismos para modular o acúmulo de íons. Genes que codificam transportadores d
Genetics and Molecular Biology. Publicado em: 2001-12
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12. Produção e caracterização parcial de um composto de baixa massa molecular com atividade fenoloxidasica, de Thermoascus aurantiacus
This work involves the phenoloxidase activity (POx) production by the thermophilic fungus Thermoascus auralltiacus. The best conditions for POx activity production in liquid culture were determined. The addition of lignocellulosic and polyssacharides substrates to culture induced high leveI POx activity. The best substrate was the wheat bran which induced be
Publicado em: 1995