Chromogranin A
Mostrando 1-12 de 64 artigos, teses e dissertações.
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1. Non-functional paraganglioma of urinary bladder managed by transurethral resection
ABSTRACT Purpose As a rare bladder tumor, paraganglioma of the urinary bladder (PUB) is frequently misdiagnosed as bladder cancer, particularly for the non-functional type. To date, transurethral resection remains a controversial treatment for non-functional PUB. This study aimed to identify the clinical features, pathological characteristics, prognosis, a
Int. braz j urol.. Publicado em: 07/11/2019
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2. Effect of non-surgical periodontal therapy on the degree of gingival inflammation and stress markers related to pregnancy
Abstract Objectives The purpose of this study was to determine the impact of nonsurgical periodontal therapy considering the salivary stress-related hormone and cytokine levels in the gingival crevicular fluid (GCF) on pregnant and nonpregnant women. Material and Methods Thirty non-pregnant (control group) and 30 pregnant women (test group) that met the st
J. Appl. Oral Sci.. Publicado em: 23/07/2018
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3. A rare case of ectopic ACTH syndrome originating from malignant renal paraganglioma
SUMMARY Ectopic adrenocorticotropic hormone (ACTH) syndrome is characterized by hypercortisolism due to the hypersecretion of a non-pituitary ACTH-secreting tumor leading to Cushing’s syndrome. Only a few cases have been reported previously as causing ectopic ACTH related to paraganglioma. Herein, we present a case of Cushing’s syndrome, in who was prove
Arch. Endocrinol. Metab.. Publicado em: 13/02/2017
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4. Diagnostic work-up of gastroenteropancreatic neuroendocrine tumors
Neuroendocrine tumors are a heterogeneous group of malignancies that present a diagnostic challenge. The majority of patients (more than 60%) present with metastatic disease at diagnosis. The diagnosis is based on histopathology, imaging, and circulating biomarkers. The histopathology should contain specific neuroendocrine markers such as chromogranin A, syn
Clinics. Publicado em: 2012
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5. Determinação do limiar anaeróbio por meio de biomarcadores salivares: cromogranina A como novo marcador de intensidade em natação
CAPITULO 2: Este estudo investigou a variação intra-individual do lactato (sLac), alfa-amilase (sAA) e cromogranina A (sCgA) salivares com relação ao acúmulo de lactato sanguíneo (bLac) durante um teste de exercício incremental máximo em natação. Amostras de sangue e saliva foram coletadas de doze atletas profissionais da natação durante um teste
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/07/2011
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6. Dinâmica de Marcadores Salivares de Atividade Autônoma e Adrenocortical em Resposta à Competição de Elite
CAPÍTULO 2: O presente estudo investigou a variação da resposta do cortisol ao acordar (CAR) em relação com estados de humor e desempenho durante uma competição de natação profissional. Onze atletas foram examinados durantes dois dias consecutivos de competição. Em cada dia, a concentração de cortisol salivar foi determinada ao acordar, 30 e 60
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/07/2011
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7. Parallel determination of NeuroD1, Chromogranin-A, KI67 and androgen receptor expression in surgically treated prostate cancers
PURPOSE: Neuroendocrine differentiation is a hallmark of prostate cancer. The aim of our study was the detection of the parallel expression of neuroendocrine related markers using a prostate tissue microarray (TMA). MATERIALS AND METHODS: Our study was aimed at detecting the parallel expression of NeuroD1, Chromogranin-A (ChrA), Androgen Receptor (AR) and Ki
International braz j urol. Publicado em: 2011-02
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8. Prognostic value of morphologic and clinical parameters in pT2 - pT3 prostate cancer
OBJECTIVES: Verify the efficacy of clinical and morphologic parameters currently applied, including an immunohistochemical panel, in the prognostic of prostate cancer, in specific stages of the disease MATERIALS AND METHODS: In the period from 2002 to 2005, 40 surgical specimens were selected from patients submitted to radical prostatectomy, with their respe
International braz j urol. Publicado em: 2007-10
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9. Perfil imunoistoquímico dos tumores neuroendócrinos
Neuroendocrine tumours are a group of neoplasias that share morfofuncional characteristics but have a great variety of location, histogenesis, clinical presentation and prognosis. This study tests the immunohistochemistry profile of immunostaining to determine histogenetic characteristics and correlations with biological behavior determining factors. Twenty
Publicado em: 2007
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10. Chromogranin A processing and secretion: specific role of endogenous and exogenous prohormone convertases in the regulated secretory pathway.
Chromogranins A and B and secretogranin II are a family of acidic proteins found in neuroendocrine secretory vesicles; these proteins contain multiple potential cleavage sites for proteolytic processing by the mammalian subtilisin-like serine endoproteases PC1 and PC2 (prohormone convertases 1 and 2), and furin. We explored the role of these endoproteases in
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11. Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist.
Catecholamine secretory vesicle core proteins (chromogranins) contain an activity that inhibits catecholamine release, but the identity of the responsible peptide has been elusive. Size-fractionated chromogranins antagonized nicotinic cholinergic-stimulated catecholamine secretion; the inhibitor was enriched in processed chromogranin fragments, and was liber
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12. Chromogranin A in children with neuroblastoma. Serum concentration parallels disease stage and predicts survival.
Chromogranin A is an acidic protein costored and coreleased with catecholamines from storage vesicles. Its serum concentration is elevated in patients with peptide-producing endocrine neoplasia. We measured serum chromogranin A at the time of diagnosis in 34 children with all stages of neuroblastoma. With a sensitivity of 91% and specificity of 100%, serum c