Compostos Pirimidanicos Santese E Avaliaaao
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1. Novas pirimidinas: sÃntese e avaliaÃÃo de suas propiedades farmacolÃgicas
This work describes the synthesis of three series of compounds with pirimidinic ring and its pharmacological evaluations. First, the synthesis of compounds 4-amino-2,6-(diaryldissubistituted)- 5-carbonitrile-pyrimidines (5a-h) were achieved starting from arylamidine and bisnitriles. Second, the nitro-compounds (5k-o) have been reduced to their respective ami
Publicado em: 2003