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1. Produção de mutantes de Streptomyces clavuligerus nos genes lat, cvm7P e rpoZ e estudo de seus efeitos sobre a produção de ácido clavulânico / Production of Streptomyces clavuligerus mutants in the genes lat, cvm7P and rpoZ, and study their effects on acid production clavulanic
Molecular biology and genetic engineering have been deployed widely in recent years, several protocols have been established, presenting new methodologies capable of altering the genetics of bacterial strains industrial interest. This research had as main objectives: (1) the construction of the following plasmids: plat, pAMB4 and pAMB3RpoZneo, (2) th
Publicado em: 2010