Crcs
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. The Prognostic Roles of PYCR2 and ZBTB18 Expression in Tissues of Colorectal Carcinoma and Non-Neoplastic Tissues: An Immunohistochemical Study
Abstract Background It is important to detect novel biomarkers responsible for the progression and spread of colorectal cancer (CRC) to better evaluate the prognosis of the patients, provide better management, and foster the development of therapeutic targets. In humans, pyrroline-5-carboxylate reductase 2 (PYCR2) is encoded on chromosome 1q42.12, and its m
Journal of Coloproctology (Rio de Janeiro). Publicado em: 2022
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2. Origin, transfer and distribution of cantharidin-related compounds in the blister beetle Hycleus scabiosae
Cantharidin provides chemical protection for the coleopteran families Meloidae and Oedemeridae. In the present study, it was observed that cantharidin concentration in Hycleus scabiosae was slightly decreased from mated females (mean = 0.011 mg/mg of dry weight) to males (mean = 0.010 mg/mg) and considerably diminished in relation to virgin females (mean = 0
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2012
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3. Avaliação das alterações do gene VHL nos carcinomas renais de células claras associados à síndrome de von Hippel-Lindau
A Síndrome de von Hippel-Lindau é uma doença hereditária multissistêmica, causada por mutações germinativas no gene VHL que predispõe o portador a manifestações benignas e malignas em diversos órgãos. Entre esses eventos, o carcinoma de células claras renais (CRC) é o de pior prognóstico, com uma penetração média de 25% e sendo a principal
Publicado em: 2010
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4. As fraudes nas gestões empresariais e a co-responsabilidade dos profissionais da contabilidade
O problema da corrupção na profissão contábil ocorre quando o profissional se encontra diante da possibilidade de obter vantagem pessoal numa determinada situação, quando é coagido a pratica delito em decorrência de sua posição privilegiada na situação, quando se permite associar com pessoas para a prática de atos que contrariam a legislação,
Publicado em: 2010
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5. Detection of cantharidin-related compounds in Mylabris impressa (Coleoptera: Meloidae)
Cantharidin is mainly found in the beetle families Meloidae and Oedemeridae (Insecta: Coleoptera) which are the natural producers of this terpene anhydride. Most studies to date have focused on cantharidin distribution in blister beetles, with few reports on recently found cantharidin-related compounds (CRCs). Using gas chromatography-mass spectrometry (GC-M
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2007
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6. Periapical tissue healing after post space preparation with or without use of a protection plug and root canal exposure to the oral environment: study in dogs
O propósito deste trabalho foi avaliar a influência da infiltração coronária no reparo dos tecidos periapicais após obturação dos canais radiculares, preparo para pino e proteção ou não de um "plug" de cimento temporário. Quarenta canais de dentes de cães foram instrumentados e obturados pela técnica da condensação lateral ativa com cones de
Brazilian Dental Journal. Publicado em: 2007
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7. Influência do cimento obturador e de um "plug" na infiltração coronária após preparo para pino
O objetivo deste trabalho foi avaliar "in vitro" a infiltração marginal coronária após obturação de canal e preparo para pino, empregando-se ou não um "plug" protetor. Cem dentes humanos unirradiculares extraídos tiveram suas coroas removidas, e os canais preparados biomecanicamente e obturados pela técnica da condensação lateral com cones de guta
Journal of Applied Oral Science. Publicado em: 2004-09
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8. Identifying cluster subtypes for intentions to have colorectal cancer screening among non-compliant intermediate-risk siblings of individuals with colorectal cancer
Although first-degree relatives of colorectal cancer (CRC) patients diagnosed at an early age are at increased risk for CRC, their compliance with colorectal cancer screening (CRCS) is not high. Relatively little is known about why these intermediate-risk family members do not comply with CRCS. Study aims were to identify subgroups of siblings of individuals
Oxford University Press.
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9. Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype
Colorectal cancers (CRCs) are characterized by multiple genetic (mutations) and epigenetic (CpG island methylation) alterations, but it is not known whether these evolve independently through stochastic processes. We have recently described a novel pathway termed CpG island methylator phenotype (CIMP) in CRC, which is characterized by the simultaneous methyl
The National Academy of Sciences.
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10. Association of apolipoprotein E polymorphisms and dietary factors in colorectal cancer
ApoE single nucleotide polymorphisms (SNPs) Cys112Arg (Epsilon-4), and Arg158Cys (Epsilon-2) have been implicated in cardiovascular and Alzheimer's disease, but their role in colorectal cancer (CRC) has not been extensively studied. We investigated whether ApoE polymorphisms alone or in combination with dietary factors selectively contribute to mismatch-repa
Nature Publishing Group.
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11. Germline HNPCC gene variants have little influence on the risk for sporadic colorectal cancer.
Hereditary non-polyposis colorectal cancer (HNPCC) is a syndrome of inherited bowel and other cancers that has been said to account for up to 15% of all colorectal carcinomas (CRCs). HNPCC can now be diagnosed at the molecular level by detecting germline mutations in genes involved in mismatch repair. A current problem is to determine the prevalence of HNPCC
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12. Molecular and Clinical Characteristics of MSH6 Variants: An Analysis of 25 Index Carriers of a Germline Variant
The MSH6 gene is one of the mismatch-repair genes involved in hereditary nonpolyposis colorectal cancer (HNPCC). Three hundred sixteen individuals who were known or suspected to have HNPCC were analyzed for MSH6 germline mutations. For 25 index patients and 8 relatives with MSH6 variants, molecular and clinical features are described. For analysis of microsa
The American Society of Human Genetics.