Cromolyn Sodium
Mostrando 1-8 de 8 artigos, teses e dissertações.
-
1. Cromolyn therapy decreases dystrophic skeletal muscle necrosis / Influencia do cromoglicato de sodio no processo de necrose muscular em camundongos mdx jovens
Neste trabalho foi verificado se o cromoglicato de sódio protege os músculos distróficos de camundongos mdx da necrose. Camundongos mdx (n=8) com 14 dias de vida pós-natal, antes do início dos ciclos de degeneração e regeneração, foram tratados com cromoglicato de sódio (50mglKg/dia; intraperitoneal) por 16 dias. Camundongos mdx (n=8) com a mesma i
Publicado em: 2006
-
2. Allergy—Important Advances in Clinical Medicine: Topically Applied Corticosteroids and Cromolyn Sodium in Managing Rhinitis
-
3. The cromolyn binding protein constitutes the Ca2+ channel of basophils opening upon immunological stimulus.
Ca2+ channel opening has been proposed to be induced in the plasma membrane of mast cells and basophils upon crosslinking their Fc epsilon receptors. Here we report direct conductance measurements on planar lipid bilayers containing membrane components of rat basophils (RBL-2H3 line). These studies identify the Ca2+ channel-forming membrane component as the
-
4. Production of cromolyn sodium microparticles for aerosol delivery by supercritical assisted atomization
The purpose of this study was to produce cromolyn sodium (CS) micrometric particles with controlled particle size (PS) and PS distribution (PSD) suitable for aerosol delivery, using a supercritical fluids-based process. CS was micronized using the supercritical assisted atomization (SAA) technique at different solute concentrations in water and different pre
Springer-Verlag.
-
5. Degranulation of human mast cells induces an endothelial antigen central to leukocyte adhesion.
To understand better the role of mast cell secretory products in the genesis of inflammation, a system was developed for in vitro degranulation of human mast cells in skin organ cultures. Within 2 hr after morphine sulfate-induced degranulation, endothelial cells lining microvessels adjacent to affected mast cells expressed an activation antigen important fo
-
6. Role of mast cells and protease-activated receptor-2 in cyclooxygenase-2 expression in urothelial cells
Mast cells have been shown to play a role in development and persistence of various inflammatory bladder disorders. Mast cell-derived tryptase specifically activates protease-activated receptor-2 (PAR-2), and PAR-2 is known to be involved in inflammation. We investigated whether mast cells participate in increase of cyclooxygenase-2 (COX-2) protein abundance
American Physiological Society.
-
7. Immunoglobulin E receptor-activated calcium conductance in rat mast cells.
1. The nystatin perforated-patch method was used to record macroscopic currents from anti-trinitrophenyl (TNP) immunoglobulin E (IgE)-sensitized rat basophilic leukaemia (RBL-2H3) cells at 37 degrees C. 2. An inwardly rectifying Ca2+ current (ICa) was activated upon stimulation with the multivalent antigen trinitrophenylated bovine serum albumin (TNP-BSA). I
-
8. Evidence that capsaicin hyperaemia of rat sciatic vasa nervorum is local, opiate-sensitive and involves mast cells.
1. In previous work, we identified a prolonged and intense hyperaemic response of rat sciatic endoneurial vasa nervorum produced by epineurial application of capsaicin. We postulated that this response, which was blocked by substance P (SP) or calcitonin gene-related peptide (CGRP) antagonists, was a result of local release of neuropeptides on the 'feeding'