Dermcidin
Mostrando 1-3 de 3 artigos, teses e dissertações.
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1. The relation of dermcidin with insulin resistance and inflammation in women with polycystic ovary syndrome
SUMMARY OBJECTIVE: Polycystic ovary syndrome is the most common endocrinopathy among women of reproductive age. Polycystic ovary syndrome is a metabolic disorder associated with insulin resistance and subclinical inflammation. Dermcidin, an antimicrobial peptide, involves in insulin resistance and inflammatory processes. Dermcidin suppresses the secretion o
Revista da Associação Médica Brasileira. Publicado em: 2022
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2. Reduction of growth and resistance cellular of mammary carcinoma after silencing of gene PIF/DCD (Proteolysis-inducing Factor) by shRNAi. / Redução do crescimento e resistência celular de carcinoma mamário após silenciamento do gene PIF/DCD (Proteolysis-Inducing Factor) via shRNAi.
A expressão do PIF/DCD em tumores tem sido relacionada ao crescimento e resistência à morte celular e à indução de caquexia em camundongos. O objetivo deste estudo foi investigar o papel do PIF/DCD nestes processos. Foram construídos três PIF/DCD-RNAi chamados de IBC-I, II, III e pKLO (controle), compreendendo diferentes áreas do mRNA, geramos clone
Publicado em: 2007
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3. A neural survival factor is a candidate oncogene in breast cancer
Using serial analysis of gene expression (SAGE), we identified a SAGE tag that was present only in invasive breast carcinomas and their lymph node metastases. The transcript corresponding to this SAGE tag, dermcidin (DCD), encodes a secreted protein normally expressed only in the pons of the brain and sweat glands. Array comparative genomic hybridization, fl
National Academy of Sciences.