Diterpenoids
Mostrando 1-12 de 34 artigos, teses e dissertações.
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1. Diversity of the diterpenes in the leaves of Xylopia laevigata (Annonaceae) and their cytotoxicities
The phytochemical investigation of the hexane extract which was obtained from the leaves of Xylopia laevigata (Annonaceae) produced six terpenes. Among these, five diterpenes named abieta-7,13-dien-3-one, ent-7β-acetoxy-16β-hydroxy-kaurane, 4-epi-cupressic acid, powerol, and labdorffianic acid B, and one oxygenated sesquiterpene, spathulenol. This is the f
Quím. Nova. Publicado em: 2020-04
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2. Terpenoids isolated from Azadirachta indica roots and biological activities
Abstract The chemical study of roots from Azadirachta indica A. Juss., Meliaceae, led to the isolation of two new terpenoids, limonoid morenolide and diterpene 17-hydroxy-sandaracopimar-8,15-dien-11-one, in addition to the four well-known limonoids nimbinene, nimbinal, nimbandiol and salannin, and three diterpenoids nimbidiol, ferruginol, and 6,7-dehydroferr
Rev. bras. farmacogn.. Publicado em: 2019-02
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3. Cytotoxic activity of abietane diterpenoids from roots of Salvia sahendica by HPLC-based activity profiling
ABSTRACT Screening of medicinal plants from Iranian flora against human cancer cell-lines have shown that an hexane extract from roots of Salvia sahendica Boiss. & Buhse, Lamiaceae, is active against human cervical cancer (HeLa) and colorectal adenocarcinoma (Caco-2) cell-lines at the test concentration of 100 µg/ml (100% inhibition). Cytotoxicity of the ex
Rev. bras. farmacogn.. Publicado em: 2018-01
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4. Vouacapane diterpenoids isolated from Pterodon and their biological activities
Abstract The Pterodon genus comprises two native species in Brazil, known as “sucupira-branca” or “faveira”. Their fruits have long been used in Brazilian natural medicine, mainly for the treatment of infections and inflammations. The pharmacological properties of these fruits have often been linked with vouacapane diterpenoids. This review evaluated
Rev. bras. farmacogn.. Publicado em: 2017-10
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5. Sedative and muscle relaxant activities of diterpenoids from Phlomidoschema parviflorum
Abstract Phlomidoschema parviflorum (Benth.) Vved. (Basionym: Stachys parviflora Benth.) Lamiaceae, have significance medicinal importance as it is used in number of health disorders including diarrhea, fever, sore mouth and throat, internal bleeding, weaknesses of the liver and heart genital tumors, sclerosis of the spleen, inflammatory tumors and cancerous
Rev. bras. farmacogn.. Publicado em: 2017-10
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6. Cytotoxic diterpenoids from the roots of Salvia lachnocalyx
ABSTRACT Salvia lachnocalyx Hedge, Lamiaceae, is an endemic sage which grows naturally in the Fars Province of Iran. The phytochemical analyses of the roots of S. lachnocalyx led to the isolation of five known diterpenoids: ferruginol (1), taxodione (2), sahandinone (3), 4-dehydrosalvilimbinol (4) and labda-7,14-dien-13-ol (5). Their chemical structures were
Rev. bras. farmacogn.. Publicado em: 2017-08
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7. Two new diterpenoids from Leonurus japonicus
Abstract Two new labdane-type diterpenoids, 5-ethoxy-3-(2-((R)-4-hydroxy-2,5,5,8a-tetramethyl-3-oxo-3,5,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)furan-2(5H)-one (1), and 5-hydroxy-4-(2-((1R,3S,7aS)-1-hydroxy-4,4,7a-trimethyl-3-propionyloctahydroisobenzofuran-1-yl)ethyl)furan-2(5H)-one (2), were isolated from the EtOH extract of the herb of Leonurus japonicus
Rev. bras. farmacogn.. Publicado em: 2015-04
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8. Antifungal activity against Cryptococcus neoformans strains and genotoxicity assessment in human leukocyte cells of Euphorbia tirucalli L.
In the last times, focus on plant research has increased all over the world. Euphorbia tirucalli L., a plant known popularly as Aveloz, and originally used in Africa, has been drawing attention for its use in the United States and Latin America, both for use as an ornamental plant and as a medicinal plant. E. tirucalli L. is a member of the family Euphorbiac
Braz. J. Microbiol.. Publicado em: 2014-12
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9. Vasorelaxant effects in aortic rings of eight diterpenoids isolated from three Venezuelan plants
Vasorelaxant activity Vasorelaxant effects of eight diterpenoids isolated from three Venezuelan plants [(+)-manool [(+)-labda-8(17),14-dien-13-ol], (+)-manoyl oxide, (+)-2-oxomanoyl oxide, sandaracopimara-8(14), 15-dien-3β, 19-diol, jhanidiol acetate (18-acetoxy-1βhydroxymanoyl oxide), jhanidiol (1β,18-dihydroxymanoyl oxide),ent-kaur-16-en-19ol and grandi
Rev. bras. farmacogn.. Publicado em: 2013-10
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10. Ent-kaurane diterpenoids and other constituents from the stem of Xylopia laevigata (Annonaceae)
Phytochemical investigation of the hexane extract from the stem of Xylopia laevigata led to the isolation of the ent-kaurane diterpenoids, ent-kaur-16-en-19-oic acid, 4-epi-kaurenic acid, ent-16β-hydroxy-17-acetoxy-kauran-19-al, ent-3β-hydroxy-kaur-16-en-19-oic acid, and ent-16β,17-dihydroxy-kauran-19-oic acid, as well as spathulenol and a mixture of β-s
Quím. Nova. Publicado em: 2012
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11. Terpenóides em espécies do gênero salvia (lamiaceae) / Terpenoids in the genus Salvia (Lamiaceae)
O gênero Salvia L. (Lamiaceae), constituido de aproximadamente 900 espécies, possui 60 representantes no Brasil. Dentre suas propriedades medicinais destacam-se as atividades antitumoral, anti-inflamatória, cicatrizante e antibacteriana. Óleos essenciais e diterpenos de núcleos abietano, clerodano, primarano estão entre os principais constituintes quí
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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12. Studies of QSAR-2D applied to clerodane diperpenoids and dibenzoylhydrazines / Estudos de QSAR-2D aplicados a diterpenóides clerodanos e dibenzoilidrazinas
A tese foi organizada em forma de cinco estudos de caso de QSAR-2D, usando compostos da literatura. Foram utilizados diterpenóides clerodanos e N,N¿- dibenzoil-N-t-butilidrazinas (DBHs) para desenvolver modelos de QSAR, propondo o uso de uma metodologia que emprega análise conformacional. Os modelos de QSAR são construídos pela escolha do confôrmero qu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/08/2011