Echinococcus Multilocularis
Mostrando 1-12 de 36 artigos, teses e dissertações.
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1. Comparative analysis of the 14-3-3 gene and its expression in Echinococcus granulosus and Echinococcus multilocularis metacestodes
It was suggested that the unlimited proliferative capacity of the Echinococcus multilocularis metacestode may be related to overproduction of the 14-3-3 protein. As is known, the proliferative capacities of E. granulosus and E. multilocularis metacestodes are very different. By comparing the expression levels of the 14-3-3 gene between in vitro-obtained E. g
Publicado em: 2011
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2. Reduced genetic variability within coding and non-coding regions of the echinococcus multilocularis genome
Echinococcus multilocularis, a vulpine intestinal tapeworm, is the causative agent of alveolar echinococosis in humans, one of the most severe and lethal parasitic infections in man. To date, there is very little knowledge about the genetical polymorphism of this parasite. To assess sequence polymorphism, we analysed a sample of 33 E. multilocularis isolates
Publicado em: 2011
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3. Redundancy and recombination in the Echinococcus AgB multigene family : is there any similarity with protozoan contigency genes?
Numerous genetic variants of the Echinococcus antigen B (AgB) are encountered within a single metacestode. This could be a reflection of gene redundancy or the result of a somatic hypermutation process. We evaluate the complexity of the AgB multigene family by characterizing the upstream promoter regions of the 4 already known genes (EgAgB1-EgAgB4) and evalu
Publicado em: 2011
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4. Diversificação dos genes do antígeno B de Echinococcus multiocularis em camundongos proficientes e não proficientes quanto à resposta imune mediada por células T
O antígeno B (AgB) é uma proteína polimérica de aproximadamente 160 kDa secretada durante a fase larval dos parasitos do gênero Echinococcus. Sua função provavelmente está relacionada com a evasão da resposta imune do hospedeiro, e tem sido relatado que seus genes apresentam alta diversidade de seqüências, mesmo dentro de um único metacestóide d
Publicado em: 2008
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5. Averiguação da localização sub-telomérica dos genes do antígeno B de Echinococcus
A forma larval de Echinococcus granulosus (metacestóide) é o agente causador da hidatidose cística, zoonose endêmica no Rio Grande do Sul. Essa parasitose caracteriza-se pelo crescimento de uma massa cística preenchida de líquido hidático que causa compressão em órgãos e tecidos vizinhos. O antígeno B (AgB) é um dos maiores componentes do líquid
Publicado em: 2007
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6. Molecular Cloning of a Vaccine Antigen against Infection with the Larval Stage of Echinococcus multilocularis
Alveolar and cystic hydatidosis are caused by infection with the larval stages of Echinococcus multilocularis and Echinococcus granulosus, respectively. A host-protective antigen has been identified in E. granulosus. Here we identify the presence of a closely related protein in E. multilocularis, characterize and express a cDNA encoding the antigen (designat
American Society for Microbiology.
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7. Immunodiagnosis of Echinococcus Infections: Confirmatory Testing and Species Differentiation by a New Commercial Western Blot
The Echinococcus Western Blot IgG (LDBIO Diagnostics, Lyon, France), using a whole larval antigen from Echinococcus multilocularis, was evaluated for serodiagnosis and differentiation between two human parasitic infections of worldwide importance: cystic echinococcosis, due to Echinococcus granulosus, and alveolar echinococcosis, due to E. multilocularis. Fi
American Society for Microbiology.
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8. Protection of cotton rats against experimental Echinococcus multilocularis infections with BCG cell walls.
Previous works has indicated that cotton rats treated with Mycobacterium bovis strain BCG are effectively protected against an infection with the metastatically proliferating metacestodes of Echinococcus multilocularis. In an attempt to induce a similar protection in the absence of tubercular granulomatous lesions, cotton rats were treated with BCG cell wall
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9. Effects of multiple doses of isoprinosine on Echinococcus multilocularis metacestodes.
Isoprinosine was given at daily doses of 0.5, 1, 2, and 4 g kg-1 of body weight to jirds that were infected for 3 months with Echinococcus multilocularis metacestodes. The effects of the different drug doses on metacestodes were studied by transmission electron microscopy and biochemical methods. At lower doses, increases in uric acid and adenosine deaminase
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10. Molecular and immunological diagnosis of echinococcosis.
Echinococcosis is an infectious disease of humans caused by the larval (metacestode) stage of the cestode species Echinococcus granulosus (cystic echinococcosis or hydatid disease) or Echinococcus multilocularis (alveolar echinococcosis or alveolar hydatid disease). Clinical manifestations depend primarily on localization and size of hepatic lesions and may
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11. In Vitro Activities of Benzimidazoles against Echinococcus multilocularis Metacestodes
Alveolar echinococcosis, caused by the larval (metacestode) stage of the tapeworm Echinococcus multilocularis, is a lethal parasitosis of the liver prevalent in the Northern Hemisphere. For chemotherapy the benzimidazole derivatives mebendazole and albendazole were introduced, and their use has resulted in a significant improvement in the survival rates. How
American Society for Microbiology.
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12. Effect of Amphotericin B on Larval Growth of Echinococcus multilocularis
Alveolar echinococcosis is caused by the parasitic cestode Echinococcus multilocularis. Benzimidazoles, namely, mebendazole and albendazole, are the only drugs available for the treatment of inoperable alveolar echinococcosis. At present, no therapeutic alternative is available for patients with progressive disease under treatment or for patients who are una
American Society for Microbiology.