Enaminones
Mostrando 1-12 de 24 artigos, teses e dissertações.
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1. Synthesis of quinolinediones by catalyst-free formal aza-[3+2+1] cycloaddition of enaminones, aldehydes and meldrum's acid
Este trabalho descreve um método simples de síntese de 4-aril-tetraidroquinoline-2,5-dionas através da reação tricomponente entre enaminonas N-aril-substituídas derivadas da dimedona, aldeídos aromáticos e o ácido de Meldrum. A síntese ocorre sem o uso de catálise e aquecimento, não sendo necessário o emprego de solventes especiais ou condiçõe
J. Braz. Chem. Soc.. Publicado em: 2014-07
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2. Acoplamento de cloreto de 4-nitrofenildiazônio com nucleófilos alifáticos: experimento integrado de síntese orgânica e cristalografia de raios X
This article describes an undergraduate experiment for the synthesis of p-nitrophenyldiazonium chloride and its coupling with acetylacetone and two enaminones, 4-phenylamino-pent-3-en-2-one and 4-amino-pent-3-en-2-one, in an adaptation of a previously reported synthetic protocol. The azo dyes 4-(E)-phenylamino-3-[(E)-2-(4-nitrophenylazo)]-3-penten-2-one and
Quím. Nova. Publicado em: 2013
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3. SÍNTESE DE 1,7-FENANTROLINAS E 7-AMINOQUINOLINAS TRIFLUORMETIL SUBSTITUÍDAS / SYNTHESIS OF TRIFLUOROMETHYL SUBSTITUTED 1,7-PHENANTHROLINES AND 7-AMINOQUINOLINES
This work, at first, describes the synthesis and characterization of new series of (Z,Z)-N,N-bis(oxotrifluoroalkenyl)-1,3-phenylenediamines by the addition/elimination reaction of β-alkoxyvinyl trifluoromethyl ketones with 1,3-phenylenediamine, in 47-91 % yields. The 4-alkyl[aryl(heteroaryl)]-4-alkoxy-1,1,1-trifluoro-3-alken-2-ones, of general formula F
Publicado em: 2010
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4. NH-PIRAZÓIS E ISOXAZÓIS: SÍNTESE MECANICAMENTE ATIVADA POR GRINDING / NH-PYRAZOLES AND ISOXAZOLES: SYNTHESIS MECHANICALLY ACTIVATED BY GRINDING
The synthesis of twelve NH-pyrazoles from the cyclocondensation reaction of β-dimethylaminovinylketones ([R1C(O)C(R2)=CHN(Me)2], where R1 = Me, C6H5, 3- MeO-C6H4, 4-Me-C6H4, 4-MeO-C6H4, 4-F-C6H4, 4-Cl-C6H4, 4-Br-C6H4, 4-O2N-C6H4, fur-2-il, tien-2-il; R2 = H, 2-MeO-C6H4 and R1, R2 = -(CH2)3C(O)- with hydrazine sulfate is reported. In this work, it was al
Publicado em: 2010
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5. USING OF THE IONIC LIQUIDS IN THE SYNTHESIS OF ENONES AND ENAMINONES / UTILIZAÇÃO DE LÍQUIDOS IÔNICOS NA SÍNTESE DE ENONAS E DE ENAMINONAS
The use of ionic liquids 1-butyl-3-methylimidazolium tetrafluorborate ([BMIM] [BF4]) and 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF6]) as catalytic solvent in the synthesis of 1,1,1-trichloro(fluoro)-3-alken-2-onas [CX3C(O)C(R2)=C(R1)OR] from the reaction of enolethers or acetals with acyl halides is reported. The results obtained in the pres
Publicado em: 2009
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6. ENAMINONAS: SÍNTESE E APLICAÇÃO EM REAÇÕES DE CICLOISOMERIZAÇÃO E DE ACOPLAMENTO / Enaminones: Synthesis and application in cycloisomerization reactions and coupling
Neste trabalho é descrita a síntese de uma série de vinte 4-[alquil(aril) (2-propinilamino)]-3-alquen-2-onas [R2C(O)CH=C(R1)N(R)(CH2CCH), onde R2= CF3,CCl3, CO2Et; R1= Me, Et, Pr e R= Pr, Ph, Bn, 4-MeC6H4] obtidas com rendimentos entre 70-95%, através de uma reação de adição-1,4 seguida de substituição, entre aminas propargílicas [NH(R)(CH2CCH), o
Publicado em: 2009
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7. Acilenaminonas: Síntese e Aplicação na Obtenção de Pirazóis, Pirazolo[3,4-d]piridazinonas e Pirazolo[1,5-a]pirimidinas / Acylenaminones: Synthesis and Application in the Obtaining of Pyrazoles, Pyrazolo[3,4-d]pyridazinones and Pyrazolo[1,5-a]pyrimidines
The regioespecific synthesis of a series of 14 N-acylated enaminones (52-88%) from the acylation reaction of secondary -enamino ketones [RC(O)CH=CHNR1R2; R = Ph, 4- FC6H4, 4-NO2C6H4, thien-2-yl, CCl3, CF3; R1 = H; R2 = Bn, Ph, 4-NO2C6H4] with trifluoroacetic anhydride or ethyl oxalyl chloride in pyridine is reported. On the other hand, when tertiary enaminon
Publicado em: 2009
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8. SÍNTESE DE HETEROCICLOS VIA REAÇÕES DE CICLOCONDENSAÇÃO DE a-ETILOXALIL E -PIRAZOLIL(ALQUIL) b-DIMETILAMINOENONAS COM 1,2- OU 1,3-DINUCLEÓFILOS / SYNTHESIS OF HETEROCYCLES VIA CYCLOCONDENSATION REACTIONS OF a-ETHYLOXALYL AND -PYRAZOLYL(ALKYL) b-DIMETHYLAMINOENONES WITH 1,2- OR 1,3-DINUCLEOPHILES
Chemoselective synthesis of ethyl 4-pirimidinecarboxylates and/or ethyl 5-pirimidineoxalates via cyclocondensation reaction of b-dimethylaminoenones [R1C(=O)C(=CNMe2)C(=O)CO2Et, where R1 = Ph, 4-MeC6H4, 4-MeOC6H4, 4-BrC6H4, 4-ClC6H4, 4-FC6H4, 4-O2NC6H4, 2-thienyl, benzo[b]furan-2-yl and CF3] with NCN 1,3- dinucleophiles such as benzamidine hydrochloride or 1
Publicado em: 2009
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9. β-ENAMINONAS, 5-HIDRÓXI-4,5-DIIDROPIRAZÓIS E 5- HIDRÓXI-4,5-DIIDROISOXAZÓIS HALOMETILSUBSTITUÍDOS: ESTUDO MOLECULAR POR DIFRAÇÃO DE RAIOS-X / β-ENAMINONES, 5-HYDROXY-4,5-DIHYDROPYRAZOLE AND 5-HYDROXY-4,5-DIHYDROISOXAZOLE HALOMETHYL SUBSTITUTED: MOLECULAR STUDY BY X-RAY DIFFRACTOMETRY
The molecular study by X-ray diffraction of β-aminovinyl ketones [R3C(O)CH=C(R1)N(R4R5), onde R3 = CF3, CCl3, CHCl2; R1 = H, Me; R4 = H; R5 = benzyl, Ph, 5-methylisoxazol-3-yl; R4, R5 = -(CH2)4-, -(CH2)2O(CH2)2-], methyl 5- hydroxy-5-trihalomethyl-4,5-dihydro-1H-pyrazole-1-carboxylate [3-(R1), 4-(R2), and 5- (R3) substituted, where R1 = H, Me; R2 = H, M
Publicado em: 2008
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10. Preparações e aplicações sintéticas recentes de enaminonas
Enaminones are beta-enamino carbonylic compounds bearing the conjugated system N-C=C-C=O, which makes them versatile ambident synthetic building blocks, particularly in synthesis of heterocycles. This review covers the last three years of the literature concerning the preparation and synthetic applications of enaminones.
Química Nova. Publicado em: 2007-08
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11. Synthesis and structural study of azo-enaminones. / Síntese e estudo estrutural de azo-enaminonas.
Azoenaminones are a particular class of enaminones obtained by incorporation of azo group (N=N), on into a conjugated system N-C=C-C=O of enaminone moiety. Studies concerning of this class of organic compounds are still scarce this and of their properties and reactional behavior. Nowadays there are a few numbers this and of compounds synthesized, but the rec
Publicado em: 2006
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12. Synthesis de 3H-pyrido[2,3-b][1,4]diazepinos trifluoromethyl substituted and diazepinonas analogous / Síntese de 3H-pirido[2,3-b][1,4]diazepinos Trifluormetil Substituídos e Diazepinonas Análogas
The present research describes new synthetic methodologies for the synthesis of new series of 2-aryl(heteroaryl)-4-trifluoro-4,5-dihydro-3Hpyrido[2,3-b][1,4]diazepin-4-ols and 2-aryl(heteroaryl)-3H-pyrido[2,3-b][1,4]diazepin-4(5H)-one analogs, in a single one-pot procedure or through on intermolecular cyclization reactions of the enaminoketones intermediates
Publicado em: 2006