Endothelium Dependent Vasodilatation
Mostrando 1-12 de 39 artigos, teses e dissertações.
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1. Gender differences in microcirculation: Observation using the hamster cheek pouch
OBJECTIVES: Estrogen has been shown to play an important protective role in non-reproductive systems, such as the cardiovascular system. Our aim was to observe gender differences in vivo with regard to the increase in macromolecular permeability and leukocyte-endothelium interaction induced by ischemia/reperfusion as well as in microvascular reactivity to v
Clinics. Publicado em: 2013-12
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2. Endothelial dysfunction in cardiovascular and endocrine-metabolic diseases: an update
The endothelium plays a vital role in maintaining circulatory homeostasis by the release of relaxing and contracting factors. Any change in this balance may result in a process known as endothelial dysfunction that leads to impaired control of vascular tone and contributes to the pathogenesis of some cardiovascular and endocrine/metabolic diseases. Reduced e
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-09
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3. Gynura procumbens Merr. decreases blood pressure in rats by vasodilatation via inhibition of calcium channels
INTRODUCTION: Gynura procumbens has been shown to decrease blood pressure via inhibition of the angiotensinconverting enzyme. However, other mechanisms that may contribute to the hypotensive effect have not been studied. OBJECTIVES: To investigate the cardiovascular effects of a butanolic fraction of Gynura procumbens in rats. METHODS: Anaesthetized rats wer
Clinics. Publicado em: 2011
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4. Avaliação funcional do endotelio venoso e arterial em pacientes com hipertensão arterial refrataria / Functional evaluation of venous and arterial endothelium in patients with refractory hypertension
Refractory Hypertension (RH) is conventionally defined as a persistent elevation in blood pressure (systolic >140 or diastolic >90 mmHg), even on a triple drug regimen at maximal doses including a diuretic, in patients with good adhesion and without secondary causes of hypertension or pseudo-hypertension. When exposed to risk factors, such as hypertension, t
Publicado em: 2009
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5. Fitoquímica e atividade vasodilatadora "in vitro de" "Mansoa hirsuta D.C.".
Mansoa hirsuta DC (Bignoniaceae) is a liana found in the Atlantic forest. There is no record of ethnomedical use for this species, although its leaves have been reported to inhibit in vitro the angiotensin-converting enzyme (ACE). The goal of the present study was to evaluate the potential antihypertensive effect of this species and to isolate the bioactive
Publicado em: 2008
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6. Local alterations induced by the toxic secretion of Philodryas patagoniensis (Serpentes: Colubridae) / Alterações locais induzidas pela secreção tóxicas de Philodryas patagoniensis (Girard, 1857) (Serpentes: Colubridae)
The venom of Philodryas patagoniensis causes important and similar local lesions the ones that happen in the botropic accidents. The mechanisms involved in the local actions of this venom are little known. This study has as objective investigates the morphologic and inflammatory local actions of the venom of Philodryas patagoniensis and the mechanisms involv
Publicado em: 2008
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7. Endothelium-dependent and -independent hepatic artery vasodilatation is not impaired in a canine model of liver ischemia-reperfusion injury
We investigated whether hepatic artery endothelium may be the earliest site of injury consequent to liver ischemia and reperfusion. Twenty-four heartworm-free mongrel dogs of either sex exposed to liver ischemia/reperfusion in vivo were randomized into four experimental groups (N = 6): a) control, sham-operated dogs, b) dogs subjected to 60 min of ischemia,
Brazilian Journal of Medical and Biological Research. Publicado em: 2007-06
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8. Treinamento aeróbio de alta intensidade melhora a vasodilatação dependente do endotélio em pacientes com síndrome metabólica ou diabetes mellitus tipo 2
Introdução: A doença cardiovascular é a principal causa de morbidade e mortalidade em pacientes com síndrome metabólica ou diabetes mellitus tipo 2. Como a disfunção endotelial precede o desenvolvimento da doença cardiovascular, seria desejável identificar e tratar a disfunção endotelial antes que a aterosclerose se desenvolva. Hoje, existe evid�
Publicado em: 2007
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9. Endothelium-dependent relaxation in response to poly-L-arginine in canine coronary arteries: implications about hyperpolarization as a mechanism of vasodilatation
OBJECTIVE: To study the mechanism by which poly-L-arginine mediates endothelium-dependent relaxation. METHODS: Vascular segments with and without endothelium were suspended in organ chambers filled with control solution maintained at 37ºC and bubbled with 95% O2 / 5% CO2. Used drugs: indomethacin, acetycholine, EGTA, glybenclamide, ouabain, poly-L-arginine,
Arquivos Brasileiros de Cardiologia. Publicado em: 2003-06
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10. Efeitos da administração aguda de vitamina C na reatividade vascular arterial e venosa em tabagistas
Background: Chronic smoking is associated with endothelial dysfunction. Vitamin c, an antioxidant, improves the endothelium-mediated vasodilatation in arteries in smokers. There is significant heterogeneity of endothelial function within the circulation. Since veins are generally not susceptible to atherosclerosis, this model allows comparable assessment of
Publicado em: 2003
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11. Estudo comparativo da reatividade vascular em tabagistas, diabeticos e hipertensos
Cigarette smoking, non-insulin-dependent diabetes mellitus and essential hypertension are stablished risk factors for atherosclerosis and premature cardiovascular disease. Heavy smokers, uncompensated diabetics and patients with uncontrolled essential hypertension show impaired arterial vasodilatation which results ftom endothelial dysfunction, a key factor
Publicado em: 2000
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12. Acetylcholine released from guinea-pig submucosal neurones dilates arterioles by releasing nitric oxide from endothelium.
1. The role of the endothelium as an effector of the neurogenic cholinergic vasodilatation in submucosal arterioles of the guinea-pig ileum was investigated by measuring changes in arteriolar diameter in response to exogenous application of muscarine or electrical stimulation of the submucosal ganglia. 2. NG-Monomethyl-L-arginine (L-NMMA), an inhibitor of ni