Epidermal Growth Factor
Mostrando 1-12 de 1819 artigos, teses e dissertações.
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1. Scanning electron microscopy of panitumumab-induced eyelash and hair alterations - Pili canaliculi
Abstract Panitumumab is a monoclonal antibody against the epidermal growth factor receptor used in metastatic colorectal cancer; in addition to tumor cells, it acts on epidermal keratinocytes and on the outer root sheath and presents skin toxicity in up to 90% of cases. A scanning electron microscope was used to examine the eyelashes and hairs of a 65-year-o
Anais Brasileiros de Dermatologia. Publicado em: 2022
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2. Differential Tolerance of Clones of Eucalyptus grandis Exposed to Drift of the Herbicides Carfentrazone-Ethyl and Glyphosate
RESUMO: A deriva dos herbicidas carfentrazone-ethyl e glyphosate pode afetar o crescimento inicial do eucalipto. Este trabalho objetivou avaliar o efeito da deriva de carfentrazone-ethyl e glyphosate sobre a fotossíntese, a morfoanatomia foliar e o crescimento inicial de dois clones de Eucalyptus grandis. Foram realizados dois ensaios em esquema fatorial 2
Planta daninha. Publicado em: 15/05/2019
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3. Comparative analysis of the histopathological and epidemiological profile of ductal and lobular breast carcinomas diagnosed at the Hospital de Clínicas da Universidade Federal do Paraná during the period 2008-2013
RESUMO Introdução: O câncer da mama éa segunda causa de morte por câncer entre as mulheres em todo o mundo, e estuáis epidemiológicos podem auxiliar no entendimento dos seus mecanismos. Objetivos: Realizar um levantamento do número de casos dos carcinomas da mama diagnosticados em um período de seis anos. Método: Foi comparado com a literatura o
J. Bras. Patol. Med. Lab.. Publicado em: 09/05/2019
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4. Milk fat globule-epidermal growth factor 8 (MFG-E8) attenuates sepsis-induced acute kidney injury by inhibiting NF-κB signaling pathway
Abstract Purpose: To explore the effect of milk fat globule-epidermal growth factor 8 (MFG-E8) on sepsis-induced acute kidney injury (SAKI). Methods: Male C57BL/6 mice were randomized to control, sham, CLP, CLP+PBS, and CLP+rmMFG-E8 groups. SAKI was induced by cecal ligation and puncture (CLP). Recombinant mouse MFG-E8 (rmMFG-E8) (20 μg/kg) or PBS (vehic
Acta Cir. Bras.. Publicado em: 28/02/2019
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5. Treatment of venous ulcers with growth factors: systematic review and meta-analysis
RESUMO Objetivo: Identificar evidências acerca dos efeitos da aplicação de fatores de crescimento na cicatrização de úlceras venosas. Método: Revisão sistemática e metanálise, incluindo Ensaios Clínicos Randomizados. Buscas: Ovid MEDLINE, EMBASE, CINAHL, Cochrane CENTRAL, LILACS, Web of Science, Biblioteca Digital de Teses e Dissertações; Goog
Rev. Bras. Enferm.. Publicado em: 2019-02
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6. Development of radioimmunoconjugate for diagnosis and management of head-and-neck subclinical cancer and colorectal carcinoma
ABSTRACT Scientific innovations in diagnostic methods are important drivers of cancer control and prevention. Noninvasive imaging of the epidermal growth factor receptor (EGFR) in head-and-neck squamous, cell carcinoma and colorectal cancer could be valuable to select patients for EGFR-targeted therapy, as well as to monitor the efficacy and occurrence of re
Braz. J. Pharm. Sci.. Publicado em: 09/04/2018
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7. Radiotherapy modulates expression of EGFR, ERCC1 and p53 in cervical cancer
Cervical cancer is a public health problem and the molecular mechanisms underlying radioresistance are still poorly understood. Here, we evaluated the modulation of key molecules involved in cell proliferation, cell cycle and DNA repair in cervical cancer cell lines (CASKI and C33A) and in malignant tissues biopsied from 10 patients before and after radiothe
Braz J Med Biol Res. Publicado em: 13/11/2017
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8. O papel das mutações IDH1/2 na patogênese dos glioblastomas secundários
RESUMO Astrocitoma difuso e glioblastoma (GBM) constituem um grupo de neoplasias astrocíticas infiltrantes difusas, que mais comumente surgem nos hemisférios cerebrais de adultos. A prevalência da transformação maligna de astrocitoma difuso para astrocitoma anaplásico e GBM varia de 40% a 75% dos casos em diferentes séries. Distintas anormalidades gen
J. Bras. Patol. Med. Lab.. Publicado em: 2017-10
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9. Punica granatum suppresses colon cancer through downregulation of Wnt/β-Catenin in rat model
Abstract This study aims to elucidate the beneficial effect of Punica granatum L., Lythraceae (pomegranate) peel extract in the management of colon cancer induced intrarectally with N-methylnitrosourea. Adult male Sprague-Dawley rats were administered N-methylnitrosourea (2 mg in 0.5 ml water/rat) intrarectally three times/week for five weeks to induce color
Rev. bras. farmacogn.. Publicado em: 2017-10
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10. Production of recombinant human epidermal growth factor in Pichia pastoris
Abstract This study was carried out to express human epidermal growth factor (hEGF) in Pichia pastoris GS115. For this aim, the hEGF gene was cloned into the pPIC9K expression vector, and then integrated into P. pastoris by electroporation. ELISA-based assay showed that the amount of hEGF secreted into the medium can be affected by the fermentation condition
Braz. J. Microbiol.. Publicado em: 2017-06
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11. Urinary excretion of EGF and MCP-1 in children with vesico-ureteral reflux
ABSTRACT Purpose The aim of this study was to investigate the urinary concentration of epidermal growth factor (EGF) and monocyte chemotactic protein-1 (MCP-1) as reflux nephropathy (RN) biomarkers before and after endoscopic treatment of moderate to severe vesico-ureteral reflux (VUR). Materials and methods A prospective study was carried out on 72 chil
Int. braz j urol.. Publicado em: 2017-06
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12. Blood levels of pro-inflammatory and anti-inflammatory cytokines during an oral glucose tolerance test in patients with symptoms suggesting reactive hypoglycemia
We evaluated the impact of postprandial glycemia on blood levels of pro-inflammatory and anti-inflammatory cytokines during an oral glucose tolerance test in non-diabetic patients with symptoms suggesting reactive hypoglycemia. Eleven patients with clinical symptoms suggesting reactive hypoglycemia received an oral glucose solution (75 g) Blood was collected
Braz J Med Biol Res. Publicado em: 11/07/2016