Epithelial Dysplasia
Mostrando 1-12 de 71 artigos, teses e dissertações.
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1. Immunoexpression of human leukocyte antigen-DR in actinic cheilitis and lower lip squamous cell carcinoma
Abstract The aim of this study was to evaluate the immunoexpression of human leukocyte antigen-DR (HLA-DR) in actinic cheilitis (AC) and lower lip squamous cell carcinoma (LLSCC), and to correlate the findings with clinical (tumor size/extent, regional lymph node metastasis, and clinical stage) and histopathological (grade of epithelial dysplasia and inflamm
Braz. oral res.. Publicado em: 29/08/2019
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2. Altered β-catenin expression in oral mucosal dysplasia: a comparative study
Objective The current study aimed to investigate the β-catenin expression in oral leukoplakia (OL) with different degrees of epithelial dysplasia and normal oral mucosa. Material and Methods Formalin-fixed, paraffin-embedded tissue samples of 39 OL (mild dysplasia n=19, moderate dysplasia n=13, and severe dysplasia n=7), and 10 normal oral mucosa (contr
J. Appl. Oral Sci.. Publicado em: 2015-10
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3. Hyaluronidases and hyaluronan synthases expression is inversely correlated with malignancy in lung/bronchial pre-neoplastic and neoplastic lesions, affecting prognosis
We collected a series of 136 lung/bronchial and 56 matched lung parenchyma tissue samples from patients who underwent lung/bronchial biopsies and presented invasive carcinoma after lung surgery. The lung/bronchial samples included basal cell hyperplasia, squamous metaplasia, moderate dysplasia, adenomatous hyperplasia, severe dysplasia, squamous cell carcino
Braz J Med Biol Res. Publicado em: 28/08/2015
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4. Differential expression of stem cell-like proteins in normal, hyperplastic and dysplastic oral epithelium
Objective The identification of stem cells (SC) remains challenging. In the human oral mucosal epithelium, these cells are believed to be in the basal layer (stem cell niche), but their exact location is unclear. The aim of this study was to examine the dysplastic oral epithelium for these SC-like proteins in order to assess their diagnostic value as biomar
J. Appl. Oral Sci.. Publicado em: 2015-02
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5. Oral potentially malignant disorders in a large dental population
Objectives Oral cancer (OC) may be preceded by clinically evident oral potentially malignant disorders (OPMDs). Oral carcinogenesis is a multistep process that begins as epithelial hyperplasia and progresses to oral epithelial dysplasia and finally to fully malignant phenotypes. The aim of our study was to estimate the prevalence of OPMDs in a large popula
J. Appl. Oral Sci.. Publicado em: 2014-12
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6. Expressão de fator de crescimento transformador Beta e inibidores teciduais de metaloproteinases 1 e 2 em próstatas caninas normais e com lesões proliferativas / Expression of tansforming growth factor B and tissue inhibitor of metalloproteianse 1 and 2 in normal canine prostates and with proliferative lessions
The canine gland has drawn interest for research due to its similarities with the human prostate and the great incidence of lesions. Moreover, the canine prostate shows high incidence of diseases. The main lesions that affect the prostate are prostatitis, benign prostatic hyperplasia (BPH), cysts and adenocarcinoma. Recently attention has been given to lesio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/03/2012
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7. Expressão de fator de crescimento transformador Beta e inibidores teciduais de metaloproteinases 1 e 2 em próstatas caninas normais e com lesões proliferativas / Expression of tansforming growth factor B and tissue inhibitor of metalloproteianse 1 and 2 in normal canine prostates and with proliferative lessions
The canine gland has drawn interest for research due to its similarities with the human prostate and the great incidence of lesions. Moreover, the canine prostate shows high incidence of diseases. The main lesions that affect the prostate are prostatitis, benign prostatic hyperplasia (BPH), cysts and adenocarcinoma. Recently attention has been given to lesio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/03/2012
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8. Atividade gelatinolítica in situ e imuno-expressão das metaloproteinases 2 e 9 em lesões potencialmente malignas e carcinomas espinocelulares bucais / In situ gelatinolytic activity and immunoexpression of metalloproteinases 2 and 9 in oral potentially malignant lesions and squamous cell carcinomas
The transition from normal oral mucosa to invasive carcinoma has a complex and multifactorial etiology. Oral leukoplakia (OL) is regarded as the most prevalent potentially malignant oral lesion, with a higher tendency for malignant transformation if compared to normal oral mucosa. Although an increased activity of matrix metalloproteinases (MMPs) 2 and 9 in
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2012
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9. Avaliação das atipias epiteliais, graduação das displasias e presença de proteína p53 mutada no epitélio adjacente a carcinomas epidermoides de lábio / Evaluation of epithelial atypia, degree of dysplasia and presence of mutated p53 protein in the epithelium adjacent to lip squamous cell carcinomas
O carcinoma epidermoide de lábio (CEL), que é causado pela exposição crônica e excessiva à radiação ultravioleta do sol, é precedido por uma desordem potencialmente maligna, a queilite actínica (QA). No entanto, ainda não é possível determinar quais casos de QA evoluirão para CEL. O método mais utilizado por patologistas para prever o prognós
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/10/2011
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10. Immunohistochemical expression of p53, p16 and hTERT in oral squamous cell carcinoma and potentially malignant disorders
Oral carcinogenesis is a multi-step process. One possible step is the development of potentially malignant disorders known as leukoplakia and erytroplakia. The objective of this study was to use immunohistochemistry to analyze the patterns of expression of the cell-cycle regulatory proteins p53 and p16INK4a in potentially malignant disorders (PMD) of the ora
Brazilian Oral Research. Publicado em: 2011-02
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11. Diclofenac in hyaluronic acid gel: an alternative treatment for actinic cheilitis
OBJECTIVE: Actinic cheilitis (AC) is a precancerous lesion of the lip vermillion caused by prolonged exposure to ultraviolet light. The aim of this study was to evaluate the effect of 3% diclofenac in 2.5% hyaluronic acid gel in the treatment of AC. METHODS: Thirty-four patients with chronic AC were treated twice a day with topical diclofenac during a period
Journal of Applied Oral Science. Publicado em: 2010-10
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12. Actinic lesions in fishermen's lower lip: clinical, cytopathological and histopathologic analysis
INTRODUCTION: Actinic cheilitis (AC) is considered to be a pre-malignant lesion or an incipient and superficial form of lip squamous cell carcinoma. It is commonly found in individuals whose occupational activities are related to chronic sun exposure and the definitive diagnosis is performed with biopsy. Althoug Exfoliative cytology has been used as a screen
Clinics. Publicado em: 2010