Fumarate Hydratase
Mostrando 1-12 de 12 artigos, teses e dissertações.
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1. Hereditary leiomyomatosis and renal cell carcinoma syndrome: a case report and implications of early onset
Abstract Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an autosomal dominant manifestation of cutaneous and uterine leiomyomas together with renal cancer due to autosomal dominant germline mutations of fumarate hydratase gene. A twenty-year-old female patient presented with type-II segmental piloleiomyoma and increased menstruation due to ute
An. Bras. Dermatol.. Publicado em: 2017
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2. ESTIRIL-LACTONAS DE Cryptocarya aschersoniana Mez. (Lauraceae Juss.) COM ATIVIDADE CONTRA Meloidogyne spp. E INTERAÇÃO IN SILICO COM PROVÁVEL FUMARASE DEMeloidogyne hapla
In a previous study, substances with nematicidal properties were detected in the bark of Cryptocarya aschersoniana. Continuing such study, the methanol extract from this plant underwent fractionation guided by in vitro assays with the plant-parasitic nematode Meloidogyne exigua. Two active compounds were isolated and identified by spectroscopic methods as (E
Quím. Nova. Publicado em: 2016-02
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3. Clonagem, expressão heteróloga e caracterização do gene LmjF24.0320 que codifica a enzima fumarato hidratase em Leishmania major / Cloning, heterologous expression and characterization of the gene LmjF24.0320 that encodes the enzyme fumarate hydratase in Leishmania major.
Leishmania é um protozoário parasito flagelado responsável pela Leishmaniose, doença que afeta 88 países, distribuídos em 4 continentes, e que causa um risco a aproximadamente 350 milhões de pessoas. Estudos recentes em tripanosomatídeos, utilizando Trypanosoma brucei como modelo, sugerem que as enzimas fumarato hidratase, enzimas que catalisam a hid
Publicado em: 2009
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4. Citrate Cycle and Related Metabolism of Listeria monocytogenes
The growth response of Listeria monocytogenes strains A4413 and 9037-7 to carbohydrates was determined in a defined medium. Neither pyruvate, acetate, citrate, isocitrate, α-ketoglutarate, succinate, fumarate, nor malate supported growth. Furthermore, inclusion of any of these carbohydrates in the growth medium with glucose did not increase the growth of Li
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5. Molecular characterization of potato fumarate hydratase and functional expression in Escherichia coli.
The tricarboxylic acid cycle enzyme fumarase (fumarate hydratase; EC 4.2.1.2) catalyzes the reversible hydration of fumarate to L-malate. We report the molecular cloning of a cDNA (StFum-1) that encodes fumarase from potato (Solanum tuberosum L.). RNA blot analysis demonstrated that StFum-1 is most strongly expressed in flowers, immature leaves, and tubers.
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6. Influence of increased aspartate availability on lysine formation by a recombinant strain of Corynebacterium glutamicum and utilization of fumarate.
Aspartate availability was increased in Corynebacterium glutamicum strains to assess its influence on lysine production. Upon addition of fumarate to a strain with a feedback-resistant aspartate kinase, the lysine yield increased from 20 to 30 mM. This increase was accompanied by the excretion of malate and succinate. In this strain, fumaric acid was convert
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7. Screening for microorganisms producing D-malate from maleate.
More than 300 microorganisms were screened for their ability to convert maleate into D-malate as a result of the action of maleate hydratase. Accumulation of fumarate during incubation of permeabilized cells with maleate was shown to be indicative of one of the two enzymes known to transform maleate. The ratio in which fumarate and malate accumulated could b
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8. Energy Metabolism in Capnocytophaga ochracea
Among the microflora of the gingival sulcus are members of the genus Capnocytophaga which have been implicated as possible etiological agents of juvenile periodontitis and systemic infectious diseases. In this study, the pathway used by C. ochracea strain 25 for generating energy from glucose was investigated. When grown in a complex medium supplemented with
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9. Acetate-nonutilizing Mutants of Neurospora crassa II. Biochemical Deficiencies and the Roles of Certain Enzymes
The levels of Krebs cycle, glyoxylate cycle, and certain other enzymes were measured in a wild-type strain and in seven groups of acetate-nonutilizing (acu) mutants of Neurospora crassa, both after growth on a medium containing sucrose and after a subsequent 6-hr incubation in a similar medium, containing acetate as the sole source of carbon. In the wild str
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10. Energy metabolism of the contagious equine metritis bacterium.
The energy metabolism of the English E-CMO strain of contagious equine metritis bacterium was studied in whole cells and cell extracts. This bacterium appears to have an active Krebs cycle and probably obtains energy by oxidative phosphorylation since glycolysis and the hexose monophosphate pathways appear to be absent. These conclusions are based on the fin
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11. Anaerobic Toluene Catabolism of Thauera aromatica: the bbs Operon Codes for Enzymes of β Oxidation of the Intermediate Benzylsuccinate
The pathway of anaerobic toluene oxidation to benzoyl coenzyme A (benzoyl-CoA) consists of an initial reaction catalyzed by benzylsuccinate synthase, a glycyl radical enzyme adding the methyl group of toluene to the double bond of a fumarate cosubstrate, and a subsequent β-oxidation pathway of benzylsuccinate. Benzylsuccinate synthase has been studied in so
American Society for Microbiology.
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12. Genetic Mapping in Xenopus Laevis: Eight Linkage Groups Established
Inheritance of alleles at 29 electrophoretically detected protein loci and one pigment locus (albinism) was analyzed in Xenopus laevis by backcrossing multiply heterozygous individuals generated by intersubspecies hybridization. Pairwise linkage tests revealed eight classical linkage groups. These groups have been provisionally numbered from 1 to 8 in an arb