Galectin
Mostrando 1-12 de 74 artigos, teses e dissertações.
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1. Serum galectin-3 levels are decreased in schizophrenia
Objective: To determine whether changes in serum galectin-3 (gal-3) concentrations in schizophrenia patients have etiopathogenetic importance. Since very little research has assessed the connection between galectins and schizophrenia, we wanted to examine alterations in the inflammatory marker gal-3 in schizophrenia and investigate possible correlations bet
Braz. J. Psychiatry. Publicado em: 2020-08
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2. Effect of Artemisia apiacea Hance on growth performance, cecal opportunistic bacteria, and microbicidal peptides in rabbits
ABSTRACT This study aimed to investigate the effect of Artemisia apiacea Hance supplementation on growth performance, cecal opportunistic bacteria, and antimicrobial defense using 120 rabbits. There were four experimental diets containing a control and A. apiacea Hance added at doses of 25, 50, and 75 g kg−1 of feed. The trial lasted for 70 days. The resul
R. Bras. Zootec.. Publicado em: 28/11/2019
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3. Protein identification from the parotoid macrogland secretion of Duttaphrynus melanostictus
ABSTRACT Background: Bufonid parotoid macrogland secretion contains several low molecular mass molecules, such as alkaloids and steroids. Nevertheless, its protein content is poorly understood. Herein, we applied a sample preparation methodology that allows the analysis of viscous matrices in order to examine its proteins. Methods: Duttaphrynus melanostic
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 19/08/2019
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4. Galectin 3: an extraordinary multifunctional protein in dermatology. Current knowledge and perspectives
Abstract: Galectin 3 is a unique ~31 kDa protein that recognizes the N-acetyl-lactosamine structure of several glycoconjugates. It mainly occurs in epithelial and myeloid cells, but is also found in a variety of human cell types. In view of the crucial role played by galectin 3 in the regulation of cellular processes of essential importance and in the pathog
An. Bras. Dermatol.. Publicado em: 29/07/2019
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5. Evaluation of Galectin-3 and Myocardial Fibrosis in Patients with Hypertrophic Cardiomyopathy
Abstract Background: Galectin-3 is the designation given to the protein that binds to ß-galactosides, expressed by activated macrophages and described as a cardiac fibrosis mediator. In hypertrophic cardiomyopathy (HCM), myocardial fibrosis is an independent predictor of adverse outcome; however, the association between Galectin-3 and myocardial fibrosis
Int. J. Cardiovasc. Sci.. Publicado em: 18/02/2019
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6. Overexpression of ezrin and galectin-3 as predictors of poor prognosis of cervical cancer
The aim of this study was to explore the correlation of ezrin and galectin-3 expressions with prognosis in cervical cancer. The immunohistochemical method was applied to detect ezrin and galectin-3 expressions in normal cervix tissues (n=30), cervicitis tissues (n=28), cervical intraepithelial neoplasia (CIN) tissues (classified as I-III, n=89), and cervical
Braz J Med Biol Res. Publicado em: 23/03/2017
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7. Mecanismos de proteção da distrofia muscular : estudo proteômico e terapia farmacológica / Protective mechanisms of muscular dystrophy : proteomic study and pharmacological therapy
In Duchenne Muscular Dystrophy (DMD) and in the mdx mice model of DMD, the lack of dystrophin leads to muscle degeneration. The pathogenesis of DMD is related to sarcolemmal fragility, mechanical stress and increased influx of calcium in muscle fibers, due to dysfunction of ion channels, such as the stretch-activated calcium channels. The knowledge of the pr
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/07/2012
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8. Avaliação da interação entre galectina-1 e zinco e suas potenciais implicações estruturais e funcionais / Evaluation of the interaction between Galectin-1 and Zinc and their potential structural and functional implications
Introdução: A Galectina-1 (Gal-1) é uma proteína multifuncional capaz de reconhecer, de modo específico, glicanas compostas por resíduos de -galactosídeos, por meio de domínios de reconhecimento de carboidrato (CRD). A Gal-1 é um homodímero de 14.900 daltons, pI = 5.6, apresenta uma topologia molecular do tipo jelly-roll composto por duas folhas- a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/07/2011
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9. Expression and possible functional role of galectin-3 in the / Expressão e possível papel funcional da galectina-3 no timo de camundongos diabéticos não-obesos (NOD)
Galectin-3 belongs to a family of endogenous lectins which bind to -galactosides presented on the cell surface and extracellular matrix glycoproteins. It is involved in multiple biological functions such as cell growth, adhesion, proliferation and apoptosis. Moreover, galectin-3 is found in several tissues and organs, being highly conserved among animal spec
Publicado em: 2010
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10. Impact of galectin-1 on the evolution of acute experimental Trypanosoma cruzi infection / Avaliação da participação da galectina-1 na evolução da infecção experimental aguda por Trypanosoma cruzi
Galectin-1 (Gal-1) is a -galactoside-binding protein and participates in several biological processes, including modulation of immune response. In the literature, there are several reports about the potential therapeutic use of Gal-1 for autoimmune diseases, inflammatory, degenerative and infectious diseases. However, there are few reports on the involvement
Publicado em: 2010
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11. Immunolocalization of galectin-3 in mouse public symphysis during pregnancy and post-partum / Imunolocalização de galectina-3 na sinfise pubica de camundongos durante a prenhez e pos-parto
It is recognized that the pubic symphysis of some mammal species, including mice, undergoes structural transformations during pregnancy and post-partum. These transformations include the emerging of an interpubic ligament and softening of this tissue in the two last days of pregnancy. This ligament allows the pelvic bones separation, warranting fetus self pa
Publicado em: 2009
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12. Analise de possiveis mecanismos e consequencias funcionais da expressão de galectina-3 em celulas de glioma expostas a condições hipoxicas / Analysis of possible mechanisms and functional consequences of galectin-3 expression in glioma cells exposed to hypoxia
Gliomas are primary Central Nervous System tumors. Among them, glioblastomas are the most common clinical forms and have the worst prognosis. In an attempt to understand glioma biology, the NG97 cell line was established. This cell line presents glioblastoma s characteristics, showing nuclear atipia and high growth rate. Recently, it was discovered that this
Publicado em: 2009