Genetic Modification
Mostrando 1-12 de 477 artigos, teses e dissertações.
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1. Polymorphisms in the heme oxygenase-1 and bone morphogenetic protein receptor type 1b genes and estimated glomerular filtration rate in Brazilian sickle cell anemia patients
ABSTRACT Introduction Mutations affecting genes involved in oxidative and signaling pathways may be associated with kidney disease in sickle cell anemia. We determined the allele and genotype frequencies of some polymorphisms in the promoter regions of the Heme Oxygenase-1 (HMOX1) [rs2071746 (A > T) and (GT)n repeats, short (S) and long (L) alleles] and Bon
Hematol., Transfus. Cell Ther.. Publicado em: 2021-06
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2. A new proposal for the m + a methodology in segregating populations of cowpea
ABSTRACT The evaluation of segregating populations in plant breeding programs is an onerous and time-consuming process. Early identification of populations with genetic potential can be done by m + a methodology. However, the possibility of a modification in the traditional methodology in order to make it more efficient, that is, faster and cheaper, was envi
Bragantia. Publicado em: 2020-06
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3. Edição genética: riscos e benefícios da modificação do DNA humano
Resumo O artigo analisa discussões sobre edição genética humana encontradas em artigos científicos, declarações institucionais e proferidas no International Summit on Gene Editing realizado em 2015. Objetiva-se explicitar e refletir sobre argumentos favoráveis e contrários à modificação do DNA. A edição genética pode desenvolver novas terapêu
Rev. Bioét.. Publicado em: 01/07/2019
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4. Triple categorical regression for genomic selection: application to cassava breeding
ABSTRACT: Genome-wide selection (GWS) is currently a technique of great importance in plant breeding, since it improves efficiency of genetic evaluations by increasing genetic gains. The process is based on genomic estimated breeding values (GEBVs) obtained through phenotypic and dense marker genomic information. In this context, GEBVs of N individuals are c
Sci. agric. (Piracicaba, Braz.). Publicado em: 20/05/2019
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5. Molecular epidemiology of 16S rRNA methyltransferase in Brazil: RmtG in Klebsiella aerogenes ST93 (CC4)
Abstract Aminoglycosides are a class of antibiotics that play a key role in antimicrobial treatment of Multidrug resistant (MDR) Gram-negative bacilli, typically in combination with β-lactams. Ribosomal 16S RNA modification by methyltransferases (e.g. RmtG) is an aminoglycoside resistance mechanism that, along with the occurrence carbapenem-resistant Entero
An. Acad. Bras. Ciênc.. Publicado em: 17/12/2018
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6. Heterochromatin distribution and histone modification patterns of H4K5 acetylation and H3S10 phosphorylation in Capsicum L.
Abstract We evaluated domesticated Capsicum pepper species from Brazil using classical and molecular cytogenetic techniques, and describe here for the first time their immunostaining patterns using anti-H4K5ac and anti-H3S10ph antibodies. All accessions showed 2n = 24 chromosomes with metacentric and submetacentric morphologies. CMA3 patterns ranged from fou
Crop Breed. Appl. Biotechnol.. Publicado em: 2018-04
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7. Components of sustainable animal production and the use of silvopastoral systems
ABSTRACT There is an urgent need for sustainable animal production systems. A system or procedure is sustainable if it is acceptable now and if its expected future effects are acceptable, in particular in relation to resource availability, consequences of functioning, and morality of action. What might make any animal usage system unsustainable? The system m
R. Bras. Zootec.. Publicado em: 2017-08
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8. The study of the ground plane effect on a Multiband PIFA Antenna by using Genetic Algorithm and Particle Swarm Optimization
Abstract The ground plane plays an important role on the performance of a planar inverted-F antenna (PIFA). In this regard, the ground plane modification using slots is proposed in this research to obtain a dual band antenna for WiMAX application. Popular optimization techniques, as genetic algorithm (GA) and particle swarm optimization (PSO), were used to d
J. Microw. Optoelectron. Electromagn. Appl.. Publicado em: 2016-12
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9. AMINOGLYCOSIDE RESISTANCE GENES IN Pseudomonas aeruginosa ISOLATES FROM CUMANA, VENEZUELA
The enzymatic modification of aminoglycosides by aminoglycoside-acetyltransferases (AAC), aminoglycoside-adenyltransferases (AAD), and aminoglycoside-phosphotransferases (APH), is the most common resistance mechanism in P. aeruginosa and these enzymes can be coded on mobile genetic elements that contribute to their dispersion. One hundred and thirty seven P.
Rev. Inst. Med. trop. S. Paulo. Publicado em: 22/03/2016
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10. Acceptance of a food of animal origin obtained through genetic modification and cloning in South America: a comparative study among university students and working adults
AbstractWith the aim of comparing the acceptance of milk obtained from cloned, genetically modified (GM) and conventionally bred cows among working adults and university students, and identifying and characterizing typologies among both subsamples in terms of their preferences, a survey was applied to 400 people in southern Chile, distributed using a simple
Food Sci. Technol. Publicado em: 15/09/2015
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11. Use of the heteroduplex mobility assay and cell sorting to select genome sequences of the CCR5 gene in HEK 293T cells edited by transcription activator-like effector nucleases
Engineered nucleases such as zinc finger nucleases (ZFN) and transcription activator-like effector nucleases (TALEN) are one of the most promising tools for modifying genomes. These site-specific enzymes cause double- strand breaks that allow gene disruption or gene insertion, thereby facilitating genetic manipulation. The major problem associated with this
Genet. Mol. Biol.. Publicado em: 2014
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12. Rutting prediction of asphalt mixtures modified by polypropylene fibers via repeated creep testing by utilising genetic programming
A novel application of genetic programming (GP) for modelling and presenting closed form solutions to the rutting prediction for polypropylene (PP) modified asphalt mixtures is investigated. Various PP fibers have been utilised for bitumen modification and repeated creep (RC) tests have been carried out. Marshall specimens, fabricated with multifilament 3 mm
Mat. Res.. Publicado em: 01/02/2013