Germinal Center
Mostrando 1-12 de 116 artigos, teses e dissertações.
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1. Morfohistología testicular de Ceratophrys ornata (Bell) (Amphibia, Anura, Ceratophryidae)
This paper describes the morphohistological features of the testes of adult Ceratophrys ornata (Bell, 1843) (n = 5) from a wetland agroecosystem of central Argentina. The testes were processed by routine histological techniques, sectioned at 8 µm. The sheets obtained were stained with hematoxylin-eosin and Masson trichrome. The gonads are paired, yellowish,
Iheringia, Sér. Zool.. Publicado em: 2013-06
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2. Expression of immunohistochemical markers in patients with AIDS-related lymphoma
AIDS-related lymphomas (ARL) present high biological heterogeneity. For better characterization of this type of lymphoma, the objectives of the present study were to evaluate the expression of immunohistochemical markers of cell differentiation (CD10, Bcl-6, MUM-1) and determine cell origin profile according to Hans' classification of diffuse large B-cell ly
Brazilian Journal of Infectious Diseases. Publicado em: 2012-02
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3. Analysis of CD10, BCL-6 and MUM1 im primary mediastinal large B cell lymphomas / Análise de CD10, BCL-6 e MUM1 em linfomas não Hodgkin de células B primários de mediastino
INTRODUÇÃO: Os linfomas B atualmente podem ser agrupados de acordo semelhanças moleculares e imunoistoquímicas com o linfócito do centro germinativo (CG) ou linfócito ativado (LA/pós CG), sendo este de pior prognóstico. O objetivo deste trabalho foi analisar a expressão de CD10, BCL-6 e MUM1 em pacientes portadores de LBPM e correlacionar com progn�
Publicado em: 2010
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4. Formação do epitelio germinativo durante a morfogenese e diferenciação gonodal em Cyprinus carpio (Teleostei:Cypriniformes) : analise estrutural e ultraestrutural das celulas germinativas e somaticas / Formation of germinal epithelium during gonodal morphogenesis and differentiation in Cyprinus carpio (Teleostei:Cypriniformes) : a structural and ultrastructural analysis of the germ and somatic cells
The description of gonadal morphogenesis in Cyprinus carpio provides a new vision of proliferation and differentiation of germ and somatic cells from the gonadal primordium leading to the formation of different ovarian and testicular structures, and the constitution of germinal epithelium which borders the ovigerous lamellae and the seminiferous tubules. In
Publicado em: 2009
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5. Primary bone lymphomas : comparison of the immunoexpression of apoptosis related proteins and adhesion molecules with nodal lymphomas and lymphomas metastatic to bone / Linfomas osseos primarios : estudo comparativo com linfomas nodais e linfomas osseos metastaticos quanto a imunoexpressão de proteinas relacionadas a apoptose, regulação do ciclo celular e adesão celular
The incidence of extranodal lymphomas is increasing in the last decades. Around 20 to 40% of B-cell non-Hodgkin lymphomas (NHL) arise outside the lymph nodes and may present distinct biological behavior, as compared to the corresponding nodal counterpart of similar histological grade. The heterogeneity of large B-cell lymphomas (LBCL) has been matter of vari
Publicado em: 2008
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6. "Gene expression profiling of mantle cell lymhoma in leukemic phase with oligonucleotide microarrays" / "Análise do perfil de expressão gênica do linfoma de células do manto em fase leucêmica com microarrays de oligonucleotídeos"
Mantle cell lymphoma is associated with the translocation t(11;14)(q13;32) and overexpression of cyclin D1. Mantle cell lymphoma is predominantly disseminated at diagnosis and a frank leukemic phase is detected in one third of patients. The pre-germinal-center naive B-cells, which populate the mantle zone of the secondary lymphoid follicles, are the cells of
Publicado em: 2005
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7. Immunoexpression of CD95 in chronic gastritis and gastric mucosa-associated lymphomas
CD95 (Fas/APO-1)-mediated apoptosis plays an important role in immunological regulation and is related to the pathogenesis of autoimmune diseases. Immunoexpression of CD95 has been reported to frequently occur in low grade non-Hodgkin lymphomas, especially of post-germinal center histogenesis, among which those originating in mucosa-associated lymphoid tissu
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-09
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8. Speckled-like Pattern in the Germinal Center (SLIP-GC), a Nuclear GTPase Expressed in Activation-induced Deaminase-expressing Lymphomas and Germinal Center B Cells*
We identified a novel GTPase, SLIP-GC, with expression limited to a few tissues, in particular germinal center B cells. It lacks homology to any known proteins, indicating that it may belong to a novel family of GTPases. SLIP-GC is expressed in germinal center B cells and in lymphomas derived from germinal center B cells such as large diffuse B cell lymphoma
American Society for Biochemistry and Molecular Biology.
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9. Germinal center-associated nuclear protein (GANP) has a phosphorylation-dependent DNA-primase activity that is up-regulated in germinal center regions
Antigen stimulation induces a rapid proliferation of B cells for expansion of specific B cell clones and their further differentiation into antibody-producing cells in germinal centers of T-dependent antigen-immunized mice. Previously, we identified a 210-kDa germinal center-associated nuclear protein (GANP) that is up-regulated selectively in germinal cente
The National Academy of Sciences.
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10. A form of immunologic tolerance through impairment of germinal center development.
Primary immunization with the T-cell-dependent antigen (4-hydroxy-3-nitrophenyl)acetyl (NP) coupled to human serum albumin results in the development of two pathways of B-cell development, the extrafollicular pathway and the germinal center pathway. Soluble, deaggregated NP-human serum albumin injected before immunization results in a marked diminution of cl
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11. Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjögren's syndrome.
Structures resembling germinal centers are seen in the salivary glands of patients with Sjögren's syndrome, but it is not known whether the microenvironment of these cell clusters is sufficient for the induction of a germinal center response. Therefore, we cloned and sequenced rearranged Ig V genes expressed by B cells isolated from sections of labial saliv
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12. B lymphocyte involvement in ankylosing spondylitis: the heavy chain variable segment gene repertoire of B lymphocytes from germinal center-like foci in the synovial membrane indicates antigen selection
The synovial membrane (SM) of affected joints in ankylosing spondylitis (AS) is infiltrated by germinal center-like aggregates (foci) of lymphocytes similar to rheumatoid arthritis (RA). We characterized the rearranged heavy chain variable segment (VH) genes in the SM for gene usage and the mutational pattern to elucidate the B lymphocyte involvement in
BioMed Central.