Guinea Pig Diseases
Mostrando 1-12 de 26 artigos, teses e dissertações.
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1. Laboratory animals and respiratory allergies: The prevalence of allergies among laboratory animal workers and the need for prophylaxis
OBJECTIVE: Subjects exposed to laboratory animals are at a heightened risk of developing respiratory and allergic diseases. These diseases can be prevented by simple measures such as the use of personal protective equipment. We report here the primary findings of the Laboratory Animals and Respiratory Allergies Study regarding the prevalence of allergic dis
Clinics. Publicado em: 2013-06
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2. Infecção natural por Listeria monocytogenes em cobaios Cavia porcellus / Natural infection by Listeria monocytogenes in guinea pigs (Cavia porcellus)
Listeriose foi identificada em quatro porcos-daíndia (Cavia porcellus) enviados para diagnóstico postmortem. Dois cobaios (1 e 2), apresentaram especialmente nódulos esbranquiçados multifocais no fígado e ceco, alterações que corresponderam microscopicamente a múltiplos focos necróticos associados com estruturas bacterianas basofílicas, degeneraç�
Publicado em: 2011
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3. Biologia do Amblyomma parvum, Aragão 1908 (Acari: Ixodidae) utilizando-se diferentes hospedeiros em condições de laboratório
Ticks are obligatory hematophagous ectoparasites and are thus infectious disease vectors for both humans and animals. To understand the epidemiology of tick-borne infectious diseases it is essential to know the life cycle of ticks. Amblyomma parvum is a Neotropical tick and its life cycle is poorly understood. In this work the biology of A. parvum is describ
Publicado em: 2010
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4. Avaliacao da toxicidade da n-metilglucamina no tratamento da leishmaniose tegumentar americana em servico publico de referencia de Minas Gerais
A cross-sectional study was conducted based on a retrospective analysis of 78 patients with mucocutaneous leishmaniasis (CL) treated between January 1995 and December 2005 in a Minas Gerais State public referral hospital for infectious diseases in order to evaluate N-methylglucamine toxicity. Diagnosis criteria for CL were based on epidemiology and clinical
Publicado em: 2007
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5. Anticomplementary activity of Fusobacterium polymorphum in normal and C4-deficient sources of guinea pig complement.
Fusobacterium polymorphum has been isolated from the gingival crevice in humans and has been implicated in the immunopathology of periodontal diseases. The presence of alternative complement pathway factors in gingival crevice material suggests the contribution of this process in the manifestation of the local host response. A complement consumption assay wa
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6. Comparative properties of the Charcot-Leyden crystal protein and the major basic protein from human eosinophils.
Guinea pig eosinophil granules contain a protein, the major basic protein (MBP), which accounts for more than half of the total granule protein, has a high content of arginine, and displays a remarkable tendency to form disulfide-linked aggregates. In this study we have purified a similar protein from human eosinophil granules and have compared the human MBP
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7. Ocular delayed hypersensitivity: a pathogenetic mechanism of chlamydial-conjunctivitis in guinea pigs.
We used a naturally occurring, Chlamydia psittaci-caused eye disease in guinea pigs, guinea pig inclusion conjunctivitis, as an animal model to understand both the immune response and the pathogenesis of chlamydial eye infections. When instilled into the conjunctival sac of guinea pigs that had been previously infected and were immune, viable chlamydiae or a
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8. Mechanism of therapeutic effect of high-dose intravenous immunoglobulin. Attenuation of acute, complement-dependent immune damage in a guinea pig model.
Studies were performed in in vitro and in vivo models to assess the effect of intravenous immunoglobulin (IVIG) on the development of acute complement-mediated tissue damage. IVIG significantly increased the duration of survival and frequently prevented the death of guinea pigs injected with anti-Forssman antiserum to cause lethal Forssman shock; no control
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9. Effect of Hypersensitivity Pneumonitis on the Pulmonary Defense Mechanisms of Guinea Pig Lungs
Many edemagenic and consolidating inflammatory diseases, such as virus pneumonias, of the lung are complicated by bacterial infection. Previous literature has stressed that edema and consolidation may promote bacterial proliferation by interfering with phagocytosis. To test that hypothesis, lung defense mechanisms were studied in guinea pigs with tuberculin-
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10. Effects of topical budesonide on epithelial restitution in vivo in guinea pig trachea.
BACKGROUND--Continuous epithelial shedding and restitution processes may characterise the airways in diseases such as asthma. Epithelial restitution involves several humoral and cellular mechanisms that may potentially be affected by inhaled anti-asthma drugs. The present study examines the effect of a topical steroid on epithelial restitution in vivo in the
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11. Dynamics of Gamma Interferon, Interleukin-12 (IL-12), IL-10, and Transforming Growth Factor β mRNA Expression in Primary Mycobacterium bovis BCG Infection in Guinea Pigs Measured by a Real-Time Fluorogenic Reverse Transcription-PCR Assay
The guinea pig has been utilized as a model for studying infectious diseases because its reactions closely resemble those of humans biologically and immunologically. However, the cytokine responses in this animal remain to be studied. Initially, we established a quantitative assay using a real-time reverse transcription-PCR (RT-PCR) to measure guinea pig gam
American Society for Microbiology.
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12. The induction of augmented granulocyte adherence by inflammation. Mediation by a plasma factor.
The adherence of granylocytes to surfaces, measured in vitro in nylon fiber columns, is inhibited by in vivo administration of anti-inflammatory agents. Therefore, the effect of inflammation itself was assessed in blood from patients with acute inflammatory diseases. Mean adherence in these patients was twice normal (56.4 +/- 5.6% vs. 29.4 +/- 5.2%); their p