Guinea Pig Ileum
Mostrando 1-12 de 143 artigos, teses e dissertações.
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1. Evaluation of anti-allergic and anti-anaphylactic activity of ethanolic extract of Zizyphus jujuba fruits in rodents
The present study reports the anti-allergic activity of ethanolic extract of Zizyphus jujubaMill., Rhamnaceae, and its possible mode of action. The effect of extract of Z. jujuba at different doses (250, 500 and 1000 mg/kg, orally) was simulated on studied animal models of asthma and allergy: a) milk induced eosinophilia and leukocytosis; b) compound 48/80 i
Rev. bras. farmacogn.. Publicado em: 2013-10
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2. Participação Do Cálcio Citosólico Sobre A Ação Espasmolítica Do Ácido Ent-7a-Acetoxitraquiloban-18-Óico E De Seu Derivado Hidroxilado Em Íleo Isolado De Cobaia / Partipation of cytosolic calcium in spasmolytic action of ent-7a-acetoxytrachyloban-18-oic acid and its hidroxylated derivated on guinea-pig ileum
From the stem bark of Xylopia langsdorfiana A. St.-Hil. &Tul. (Annonaceae), popularly known as pimenteria da terra, was isolated the diterpene ent-7-α-acetoxytrachyloban-18-oic acid (trachylobane-360) from which it was made a structural modification in which the acetoxy group was substituted by hydroxy generating the ent-7a-hidroxitrachyloban-18-oic aci
Publicado em: 2010
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3. Efeito de hypericum caprifoliatum cham. & schltdl. (guttiferae) sobre contrações em íleo isolado de cobaio induzidas por diferentes agonistas / Effect of Hypericum caprifoliatum Cham & Schltdl (Guttiferae) on isolated guinea pig ileum serotonin response
Na última década, o gênero Hypericum ganhou repercussão mundial devido à utilização de Hypericum perforatum para obtenção de medicamentos antidepressivos. Por esta razão, a maioria dos estudos com outras espécies do gênero centra-se nesta atividade. Porém, um dos usos populares de espécies de Hypericum nativas do sul do Brasil é no tratamento
Publicado em: 2010
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4. Efeitos de um peptídeo isolado do veneno de Crotalus durissus cascavella em íleo de cobaio e pressão arterial de ratos com hipertensão renovascular. / Effects of a peptide isolated from the venom of Crotalus durissus cascavella in guinea pig ileum and blood pressure of rats with renovascular hypertension.
Recentes estudos mostraram que o veneno de serpentes contém peptídeos potenciadores de bradicinina (BPPs), os quais reforçam seu efeito vasodilatador na musculatura lisa vascular por inibir a enzima conversora de angiotensina (ECA). Este trabalho teve como objetivo estudar um BPP isolado do veneno de Crotalus durissus cascavella (Cdc),uma serpente encontr
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 04/09/2009
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5. Participação dos canais de potássio na ação espasmolítica de Solanum agrarium Sendtner em íleo de cobaia e útero de rata / Participation of potassium channels in the spasmolytic action of Solanum agrarium Sendtner on guinea-pig ileum and rat uterus
Solanum agrarium Sendtner é conhecida popularmente por babá, gogóia e melancia da praia. O decocto da raiz é empregado popularmente como abortivo (AGRA, 1991). Em estudos anteriores, Santos et al., (2003) demonstraram que o extrato etanólico bruto obtido das partes aéreas de S. agrarium (SA-EtOH) apresentou atividade espasmolítica não seletiva em íl
Publicado em: 2009
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6. Envolvimento dos canais de potássio na ação espasmolítica do ácido 8(17), 12E, 14-labdatrieno-18-óico (labdano-302), isolado de Xylopia langsdorfiana A. St.-Hil. &Tul. em íleo isolado de cobaia / Involvement of potassium channels in the spasmolytic action of 8(17),12E, 14-labdatrien-18 oic acid (labdane-302), obtained from Xylopia langsdorfiana A. St.-Hil. &Tul. on guinea-pig ileum
8(17),12e,14-labdatrien-18 oic acid (labdane-302), is a diterpene isolated from the stem bark of Xylopia langsdorfiana A. St.-Hil. &Tul. In a preliminary study, Ribeiro (2003) demonstrated that labdane-302 inhibited the phasic contractions induced by carbachol (CCh) or histamine (IC50 = 1.7 0.5 and 0.9 0.2 x 10-5 M, respectively) on guinea-
Publicado em: 2008
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7. Pharmacological characterization of venoms obtained from Mexican toxoglossate gastropods on isolated guinea pig ileum
The protein-containing extracts prepared from the venom ducts of Conus austini, Conus spurius and Polystira albida caused a concentration-dependent inhibition of spontaneous contractions in guinea pig ileum. The most potent extract was obtained from P. albida venom ducts (IC50 = 0.11 ± 0.02 µg protein/mL). The three extracts produced a moderate inhibition
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2008
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8. Analise histologica do aparato venenifero e caracterização farmaco-bioquimica da peçonha de Vitalius dubius (Araneae, Theraphosidae) / Histological analysis of the venom apparatus and biochemical and pharmacological characterization of venom from Vitalius dubius (Araneae, Theraphosidae)
Vitalius dubius is a medium-sized, non-aggressive tarantula found in southeastern Brazil. In this work, we examined the histological organization of the venom apparatus of V. dubius and investigated some biochemical and pharmacological properties of this spider´s venom. The venom apparatus consisted of two chelicerae fitted with large fangs for prey immobil
Publicado em: 2008
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9. Chemical constituents from Bakeridesia pickelii Monteiro (Malvaceae) and the relaxant activity of kaempferol-3-O-beta-D-(6"-E-p -coumaroyl) glucopyranoside on guinea-pig ileum
The phytochemical investigation of Bakeridesia pickelii Monteiro led to the isolation of seven compounds: beta-sitosterol, a mixture of sitosteryl-3-O-beta-D-glucopyranoside and stigmasteryl-3-O-beta-D-glucopyranoside, vanillic acid, p-coumaric acid, quercetin 3-O-beta-D-glucopyranoside (isoquercitrin) and kaempferol-3-O-beta-D-(6"-E-p -coumaroyl) glucopyran
Química Nova. Publicado em: 2007-08
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10. Estratégias para prospecção e predição de peptídeos bioativos
Chapters one and two deal with the isolation and identification of bioactive peptides from the skin secretion of Phyllomedusa hypochondrialis. The first chapter demonstrates the use of protemic techniques, mainly mass spectrometry, for the study of bradykinin related peptides (BRPs) present in the amphibians secretion and freshly dissected skin fragments. Ei
Publicado em: 2007
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11. EFEITO DE EXTRATOS VEGETAIS SELECIONADOS SOBRE A MUSCULATURA LISA DO TRATO GASTRINTESTINAL / EFFECT OF SOME EXTRACTS ON SMOOTH MUSCLE OF GASTRINTESTINAL TRACT
The current study evaluated the possible antispasmodic activity of methanolic extracts, fractions and an active component from Brazilian medicinal plants on isolated guinea-pig ileum and rat duodenum preparations. Guinea-pigs of both sexes (300-350 g) and Male Wistar rats (250-300g) were sacrificed and the ileum and the duodenum muscle strips, respectively,
Publicado em: 2005
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12. Anti-inflammatory and antispasmodic activity of Ipomoea imperati (Vahl) Griseb (Convolvulaceae)
Ipomoea imperati (Convolvulaceae) lives on the sandy shores of the Brazilian coast and in other areas of the world. The anti-inflammatory activity of a methanol-water extract of the leaves of I. imperati was investigated in experimental models of acute and subchronic inflammation. Topical application of the extract (10 mg/ear) inhibited mouse ear edema induc
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-01