Head To Tail Interaction
Mostrando 1-12 de 25 artigos, teses e dissertações.
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1. Efeitos da risperidona e do haloperidol em um modelo de esquizofrenia induzido pela cetamina em camundongos / Effects of risperidone and haloperidol in a model ketamine-induced schizophrenia in mice
This study presents the actions of the antipsychotics (APC) risperidone (Risp) and haloperidol (Hal) on the behavioral effects elicited by Cetamine (Ceta), in mice in the following tests: Open-field (OF), Rota rod (RR) Tail suspension (TS), Elevated Plus-maze (EPM)- (Time in open arms-TOA; Time in closed arms -TCA), Hole Board (Time of head-dip -THD, number
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/08/2008
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2. Thermodynamic and structural studies of the head-to-tail complex of the muscular alpha-Tropomyosin / Estudos termodinâmicos e estruturais da interação cabeça-cauda da , alpha-tropomiosina muscular
Tropomiosina (Tm) é uma das proteínas que compõe o filamento fino (actina, Tm, Troponina) do sistema muscular esquelético e desempenha um importante papel na regulação da contração muscular. Tm é um coiled-coil de 284 resíduos que forma longos homopolímeros lineares através da sobreposição de onze resíduos entre os terminais de Tms adjacentes
Publicado em: 2008
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3. A high resolution protein interaction map of the yeast Mediator complex
Mediator is a large, modular protein complex remotely conserved from yeast to man that conveys regulatory signals from DNA-binding transcription factors to RNA polymerase II. In Saccharomyces cerevisiae, Mediator is thought to be composed of 24 subunits organized in four sub-complexes, termed the head, middle, tail and Cdk8 (Srb8-11) modules. In this work, w
Oxford University Press.
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4. Subdomain organization of the Acanthamoeba myosin IC tail from cryo-electron microscopy
Acanthamoeba myosin IC (AMIC) is a single-headed myosin comprised of one heavy chain (129 kDa) and one light chain (17 kDa). The heavy chain has head, neck (light chain-binding), and tail domains. The tail consists of four subdomains: a basic region (BR) (23 kDa) and two Gly/Pro/Ala-rich (GPA) regions, GPA1 (6 kDa) and GPA2 (15 kDa), flanking an Src homology
National Academy of Sciences.
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5. Oligomerization of the telomerase reverse transcriptase from Euplotes crassus
The telomerase ribonucleoprotein reverse transcriptase uses its RNA subunit as a template to synthesize telomeric repeats and maintain telomere tracts on chromosome ends. In the ciliate Euplotes crassus, the core telomerase ribonucleoprotein particle undergoes a developmentally programmed assembly into three higher order complexes after mating. Here, we prov
Oxford University Press.
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6. Mapping of the Regions Involved in Homotypic Interactions of Tula Hantavirus N Protein
Hantavirus nucleocapsid (N) protein has been suggested to form homodimers and homotrimers that are further integrated into the nucleocapsid filaments around the viral RNA. Here we report detailed mapping of the regions involved in the homotypic N protein interactions in Tula hantavirus (TULV). Peptide scan screening was used to define the interaction regions
American Society for Microbiology.
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7. Homotypic interaction and multimerization of nucleocapsid protein of tomato spotted wilt tospovirus: Identification and characterization of two interacting domains
The nucleocapsid protein (N) of tomato spotted wilt tospovirus (TSWV) plays a central role in the viral life cycle. With the aid of the yeast two-hybrid system and surface plasmon resonance analysis, homotypic interaction and multimerization of the N protein was detected. Analysis of deletion mutants identified two binding regions in the protein, located at
The National Academy of Sciences.
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8. A suggestion for naming faces of ring compounds
Discussion of the topology of interaction of ring compounds with macromolecules and receptors requires a system for naming the faces of the cyclic compound. An α/β-face nomenclature is suggested that is based on the clockwise/counterclockwise direction of ascending numbering in the ring with the lowest numbered unshared ring atom. This system is applicable
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9. The Yeast Kinesin-related Protein Smy1p Exerts Its Effects on the Class V Myosin Myo2p via a Physical Interaction
We have discovered evidence for a physical interaction between a class V myosin, Myo2p, and a kinesin-related protein, Smy1p, in budding yeast. These proteins had previously been linked by genetic and colocalization studies, but we had been unable to determine the nature of their association. We now show by two-hybrid analysis that a 69-amino acid region of
The American Society for Cell Biology.
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10. Domain structure of a mammalian myosin I beta.
We have determined the primary structure of a myosin I (called mammalian myosin I beta, MMI beta) from bovine brain and identified its functional domains. The protein was previously purified from brain and adrenal gland. Several constructs were generated and expressed in Escherichia coli as glutathione S-transferase fusion proteins and the recombinant protei
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11. Congruent Docking of Dimeric Kinesin and ncd into Three-dimensional Electron Cryomicroscopy Maps of Microtubule–Motor ADP Complexes
We present a new map showing dimeric kinesin bound to microtubules in the presence of ADP that was obtained by electron cryomicroscopy and image reconstruction. The directly bound monomer (first head) shows a different conformation from one in the more tightly bound empty state. This change in the first head is amplified as a movement of the second (tethered
The American Society for Cell Biology.
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12. Molecular structure of the cell-attachment protein of reovirus: correlation of computer-processed electron micrographs with sequence-based predictions.
The receptor-recognition interaction that initiates reovirus infection is mediated by the sigma 1 protein, located at the vertices of the icosahedral virion. We have applied computer-based image-averaging techniques to electron micrographs of negatively stained preparations of sigma 1 purified from virions (serotype 2 Jones). Combining these results with inf