Hepatic Regeneration
Mostrando 1-12 de 78 artigos, teses e dissertações.
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1. Assessment of remnant liver function and volume after selective ligation of portal vein and hepatic artery in a rat model
Abstract Purpose: To evaluate liver regeneration after selective ligation of portal vein and hepatic artery by 3D Computed Tomography in an experimental model. Methods: Sixteen Wistar rats were randomized into four equal groups: Group I- control (sham), Group II- isolated selective ligation of the hepatic artery, Group III- isolated selective ligation of t
Acta Cir. Bras.. Publicado em: 10/01/2020
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2. HEPATOPROTECTIVE EFFICACY OF METHANOLIC EXTRACT OF INDIGOFERA SUFFRUTICOSA (MILL) ON PARACETAMOL-INDUCED LIVER DAMAGE IN MICE
RESUMO CONTEXTO: Indigofera suffruticosa Mill (Fabaceae) é abundante no nordeste do Brasil e popularmente utilizada no tratamento de processos infecciosos e inflamatórios. Várias propriedades biológicas, como anti-inflamatório, anticâncer, antitumoral, hepatoprotetor e baixa toxicidade, são relatadas para esta planta. OBJETIVO: Este estudo investig
Arq. Gastroenterol.. Publicado em: 07/11/2019
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3. Pine ( Pinus densiflora ) needle extract could promote the expression of PCNA and Ki-67 after partial hepatectomy in rat
Abstract Purpose To investigate the effects of pine needle extract (PNE) on the expression of proliferating cell nuclear antigen (PCNA) and Ki-67 during liver regeneration induced by 70% partial hepatectomy (PH) in rat. Methods Forty-eight male rats (SD, 7 weeks) had surgery (70% PH). They were randomly divided into two groups. PH + PNE group was only prov
Acta Cir. Bras.. Publicado em: 19/08/2019
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4. Comparação dos efeitos das folhas de Cestrum axillare Vell. com as saponinas isoladas em caprinos
ABSTRACT: Cestrum axillare Vell. (formerly Cestrum laevigatum Schltd.), family Solanaceae, is the most important hepatotoxic plant in Brazil that causes acute poisoning. It occurs in the Southeast and Center-West regions and in coastal areas of the Northeast Brazil. Spontaneous poisoning was described in cattle, goats and sheep, with clinical signs evidenced
Pesq. Vet. Bras.. Publicado em: 2018-05
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5. Beetle (Ulomoides dermestoides) fat improves diabetes: effect on liver and pancreatic architecture and on PPARγ expression
Ulomoides dermestoides is a beetle traditionally consumed to treat diabetes. In this study, we performed a composition analysis of U. dermestoides to obtain the principal fractions, which were used to assess the effect on glycemia, liver and pancreatic architecture, and PPARγ and GLUT4 expression. Normal mice and alloxan-induced diabetic mice were administe
Braz J Med Biol Res. Publicado em: 06/04/2018
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6. The effect of the aqueous extract Peumus boldus on the proliferation of hepatocytes and liver function in rats submitted to expanded hepatectomy
ABSTRACT PURPOSE: To assess the effect of aqueous extract of Peumus Boldus (AEPB) on the liver proliferative response after parcial hepatectomy of 70% (PH) in rodents. METHODS: Twenty Wistar rats were divided in two groups: AEPB100 (whose rats received 100mg/Kg of AEPB, once a day, orally, in 4 days prior to the first surgical procedure) and Vehicle (whose
Acta Cir. Bras.. Publicado em: 2016-09
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7. Effects of ischemic preconditioning in a pig model of large-for-size liver transplantation
OBJECTIVE: In most cases of pediatric liver transplantation, the clinical scenario of large-for-size transplants can lead to hepatic dysfunction and a decreased blood supply to the liver graft. The objective of the present experimental investigation was to evaluate the effects of ischemic preconditioning on this clinical entity. METHODS: Eighteen pigs were
Clinics. Publicado em: 2015-02
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8. Evaluation of liver regeneration with use of diet supplemented with l-arginine
PURPOSE:To compare controlled liver regeneration in rats submitted to 60% hepatic resection having L-arginine supplemented diet, based on weight changes of the regenerated liver, laboratory parameters of liver function and pathological findings.METHODS:Thirty-six rats were divided into two groups, control and L- arginine. The first received standard chow and
Acta Cir. Bras.. Publicado em: 2014-09
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9. The ileum positively regulates hepatic regeneration in rats
PURPOSE: To test the hypothesis that liver regeneration after partial hepatectomy can be influenced by the ileum.METHODS:Eighteen Wistar rats were distributed into groups of six animals: 1 - ileum resection+ hepatectomy 2/3; 2 - hepatectomy 2/3, and 3 - sham. Anesthesia with ketamine and xylazine i.p., aseptic technique, analgesia with meperidine (10mg/kg s.
Acta Cir. Bras.. Publicado em: 2014-02
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10. In vitro proliferation and differentiation of hepatic oval cells and their potential capacity for intrahepatic transplantation
Hepatic oval cells (HOCs) are recognized as facultative liver progenitor cells that play a role in liver regeneration after acute liver injury. Here, we investigated the in vitro proliferation and differentiation characteristics of HOCs in order to explore their potential capacity for intrahepatic transplantation. Clusters or scattered HOCs were detected in
Braz J Med Biol Res. Publicado em: 30/07/2013
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11. Avaliação do emprego da pentoxifilina na regeneração hepática em ratos submetidos à hepatectomia parcial / Effect of pentoxifylline in liver regeneration in rats submitted to partial hepatectomy
Liver surgery has grown extraordinarily from the first planned ressection performed by Langenbuch in 1888, and the first successful orthotopic liver transplantation by Starzl in 1963 to the extended liver resections and living donors liver transplantations currently performed in many centers. It occurred, among others factors, because of the recognition of t
Publicado em: 2010
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12. Alterações celulares, moleculares e funcionais de fígados de ratas Wistar tratadas com fatores hepatotróficos / Cellular, molecular and functional alterations in rat liver treated with hepatotrophic factors
Fatores hepatotróficos (FH) possuem a capacidade de promover aumento de massa hepática em ratos e diminuição da fibrose em animais cirróticos. Os FH podem ser importantes nos casos de ressecção e transplantes hepáticos no qual o fígado remanescente necessita de um volume considerável para exercer suas funções após a cirurgia. Objetivou-se neste
Publicado em: 2010