Hepatotrophic Factors
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. Efeito da hepatectomia parcial associada à administração de fatores nutricionais hepatotróficos sobre a morfologia, função e expressão de genes pró-fibróticos na cirrose hepática em ratos Wistar induzida por tiocetamida / Effects of partial hepatectomy associated with administration of nutritional hepatotrophic factors in morphology, function and expression of pro-fibrotic genes in thioacetamide-induced liver cirrhosis in Wistar rats
The current study evaluated the role of parenteral solution of nutritional hepatotrophic factors in animals with cirrhosis undergoing partial hepatectomy. This procedure is fearful in these animals due to the possibility of acute liver failure, since removal of a liver fragment further reduces the functional capacity of an already compromised organ. Moreover
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/12/2011
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2. Fatores hepatotróficos modulam a capacidade proliferativa em cultura primária de hepatócitos de ratos normais / Hepatotrophic factors modulate the proliferative potential in primary hepatocyte cultures of normal rats
A utilização de fatores hepatotróficos (FH) tem trazido importantes avanços no tratamento de algumas doenças hepáticas. A avaliação dos efeitos dessas substâncias pode ser feita com o uso de modelos in vivo, como a regeneração hepática após a hepatectomia parcial ou in vitro, como a cultura de hepatócitos, células estreladas ou outros tipos ce
Publicado em: 2010
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3. Alterações celulares, moleculares e funcionais de fígados de ratas Wistar tratadas com fatores hepatotróficos / Cellular, molecular and functional alterations in rat liver treated with hepatotrophic factors
Fatores hepatotróficos (FH) possuem a capacidade de promover aumento de massa hepática em ratos e diminuição da fibrose em animais cirróticos. Os FH podem ser importantes nos casos de ressecção e transplantes hepáticos no qual o fígado remanescente necessita de um volume considerável para exercer suas funções após a cirurgia. Objetivou-se neste
Publicado em: 2010
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4. Modulation of extracellular matrix by nutritional hepatotrophic factors in thioacetamide-induced liver cirrhosis in the rat
Nutritional substances associated to some hormones enhance liver regeneration when injected intraperitoneally, being denominated hepatotrophic factors (HF). Here we verified if a solution of HF (glucose, vitamins, salts, amino acids, glucagon, insulin, and triiodothyronine) can revert liver cirrhosis and how some extracellular matrices are affected. Cirrhosi
Brazilian Journal of Medical and Biological Research. Publicado em: 25/09/2009
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5. Effect of hepatotrophic factors on thioacetamide-induced cirrhosis in rats / Efeito do tratamento com fatores hepatotróficos em ratas (Wistar) induzidas experimentalmente à cirrose por Tioacetamida
Cirrhosis is characterized by fibrosis and regenerative nodules, which result in the disorganization of the hepatic architecture, being considered an irreversible situation. The administration of exogenous hepatotrophic factors (EHF) could stimulate hepatic regeneration in hepatocytes cells and reduce the cirrhosis induced in rats. The aim of this work was t
Publicado em: 2006
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6. Efeito do tratamento com fatores hepatotróficos sobre o fígado de ratas (Wistar) com fibrose induzida experimentalmente / Effect of the treatment with hepatotrophic factors on the liver of rats (Wistar) with experimentally induced-fibrosis
The extraordinary capacity of growth of hepatic tissue can be stimulated by two processes, by the partial hepatectomy or by hepatotrophic substance supply. In this work, it was adopted the second option to treat rats with induced-fibrosis, verifying the effect of the hepatotrophic factors on the histopathological evaluation, the ratio volumetric of the colla
Publicado em: 2003
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7. Ethanolamine modulates the rate of rat hepatocyte proliferation in vitro and in vivo
A low molecular weight, heat-resistant hepatotrophic factor in an extract from the bovine intestinal mucosa was purified and identified as ethanolamine by structural analyses. The mode of action of ethanolamine in vitro and in vivo coincided with that of the crude extract of the tissue, indicating that ethanolamine is the active component. Ethanolamine syner
The National Academy of Sciences of the USA.