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Mostrando 1-12 de 1072 artigos, teses e dissertações.
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1. Qual a importância do exame de eletroforese de hemoglobina na APS?
A detecção precoce de portadores do traço falciforme permite o aconselhamento e/ou orientação genética aos portadores pelos profissionais da equipe de Atenção Primária à Saúde (APS), na medida em que casais de risco têm chance de optarem ou não por uma gestação, tais como tratamento de infecções e crises álgicas, profilaxia anti-infeccio
Núcleo de Telessaúde Sergipe. Publicado em: 12/06/2023
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2. Honey of Tetragonisca angustula from Southwestern Bahia: Influence of Seasonality on the Physicochemical Profile and Glioma Cell Inhibitory Effect
This study aims to analyze Tetragonisca angustula honey from southwestern Bahia for its physicochemical characteristics, phenolic compounds and glioma cell inhibitory effect, in samples from different periods of the year, dry (DP) and rainy (RP) period. The analyses showed that samples obtained in the DP and RP are statistically different for the physicochem
Journal of the Brazilian Chemical Society. Publicado em: 2023
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3. HemoTypeSC point-of-care testing shows high sensitivity with alkaline cellulose acetate hemoglobin electrophoresis for screening hemoglobin SS and SC genotypes
ABSTRACT Introduction: By providing timely actionable results for prompt management, point-of-care testing (POCT) kits have revolutionised medical care for various diseases, ranging from infectious diseases like malaria to genetic disorders, such as sickle cell disease (SCD). They are, however, underutilised in the diagnosis of SCD in developing countries,
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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4. Development and Validation of a Rapid and Reliable HPLC-FLD Method for the Quantification of Ciprofloxacin and Enrofloxacin Residues in Zea mays
The accumulation of antibiotics by plants is a currently concern associated to yield reduction and transference of antibiotic residues along the food web. Maize is a staple food in many parts of the world; it is also considered an important ingredient in animal nutrition. Considering the lack of validated analytical methods for the analysis of ciprofloxacin
Journal of the Brazilian Chemical Society. Publicado em: 2022
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5. A New Approach for Histamine Functionalized Nanoparticles as Sorbent Phase for Bar Adsorptive Microextraction (BAµE) and Determination of Parabens in Water by HPLC-DAD
In this study, for the first time, histamine-functionalized magnetic nanoparticles (HIS-MNP) were used as sorbent phase combined with bar adsorptive microextraction (BAµE) for the determination of methylparaben (MP), ethylparaben (EP), propylparaben (PP), and butylparaben (BP) in water samples by high performance liquid chromatography coupled with diode arr
Journal of the Brazilian Chemical Society. Publicado em: 2022
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6. CYP450 Metabolism of a Semisynthetic Naphthoquinone, an Anticancer Drug Candidate, by Human Liver Microsomes
CNFD (6b,7-dihydro-5H-cyclopenta[b]naphtho[2,1-d]furan-5,6(9aH)-dione) is a semisynthetic naphthoquinone derived from lawsone that has cytotoxic action in different tumor lines and anticancer activity in vivo. Therefore, this molecule is a relevant candidate for drug development, but there is still no information on its human metabolism and systemic eliminat
Journal of the Brazilian Chemical Society. Publicado em: 2022
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7. METHODS FOR EXTRACTION AND ISOLATION OF AGATHISFLAVONE FROM POINCIANELLA PYRAMIDALIS
Agathisflavone is a natural biflavone with restricted occurrence in plants. This biflavone presents several biological activities and can be important to developing new drugs. Obtaining such a molecule on a large scale for in vivo tests is a challenge. To date, there are no reports regarding its synthesis; thus, it is important to improve and develop methods
Química Nova. Publicado em: 2022
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8. Graphite-Polyurethane Composite Electrode Modified with Molecularly Imprinted Polymer for Determination of Diclofenac
A molecularly imprinted polymer (MIP) was prepared using the anti-inflammatory diclofenac (DCF) as a template. A non-imprinted polymer (NIP) was also prepared as a control. These MIP and NIP were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Brunauer-Emmett-Teller (BET), revealing a higher porosity in the fir
Journal of the Brazilian Chemical Society. Publicado em: 2022
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9. Polyphenol Profile and Quantitative Assessment of the Flavonoid Kaempferitrin in Wild and Cultivated Brazilian Amazonian Uncaria guianensis (Rubiaceae)
The Amazonian Rubiaceae species Uncaria guianensis (UG) is locally used as anti-inflammatory, antitumor, antidiabetic, anti-ulcers, and others. The phenolic content of its leaves is characterized by the great predominance of the flavonoid kaempferol-3,7-O-(α)-L-dirhamnoside (kaempferitrin). The present study quantitatively evaluates the kaempferitrin conten
J. Braz. Chem. Soc.. Publicado em: 2021-08
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10. A Comparison of the Photolytic and Photocatalytic Degradation of Triclosan: Identification of Transformation Products and Ecotoxicity Evaluation
Triclosan (5-chloro-2-(2,4-dichlorophenoxy)phenol) is commonly used as an antibacterial agent in various industrial products and is often detected in wastewater effluent. Comparison was made for triclosan degradation by photolysis and TiO2 photocatalysis (under UV irradiation (125 W)) based on analysis of transformation products, together with ecotoxicity ev
J. Braz. Chem. Soc.. Publicado em: 2021-08
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11. Nutrient content in ora-pro-nóbis (Pereskia aculeata Mill.): unconventional vegetable of the Brazilian Atlantic Forest
Abstract Ora-pro-nóbis (Pereskia aculeata Mill.) is an unconventional vegetable found in the Brazilian Atlantic Forest and consumed, mainly by the rural population who lives in this biome. The present study investigated the nutritional value and contribution potential this species to the recommendations of daily nutrient intake for adults. Moisture and ash
Food Sci. Technol. Publicado em: 2021-06
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12. Structure of prodigiosin from Serratia marcescens NJZT-1 and its cytotoxicity on TSC2-null cells
Abstract Prodigiosin, a secondary metabolite extracted from Serratia marcescens (S. marcescens), could induce apoptosis in various cancer cells, with however low toxicity on normal cells. The red pigment was extracted from a strain S. marcescens NJZT-1 isolated from soil, which had antibacterial activity. Spectral analyses (LC-ESI-MS, UV-VIS spectrophotometr
Food Sci. Technol. Publicado em: 2021-06