Hypopituitarism
Mostrando 1-12 de 58 artigos, teses e dissertações.
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1. Apoplexy in sporadic pituitary adenomas: a single referral center experience and AIP mutation analysis
ABSTRACT Objective: To analyze the clinical, laboratory, and radiological findings and management of patients with clinical pituitary apoplexy and to screen for aryl hydrocarbon receptor-interacting protein (AIP) mutations. Subjects and methods: The clinical findings were collected from the medical records of consecutive sporadic pituitary adenoma patients
Arch. Endocrinol. Metab.. Publicado em: 2021-06
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2. Management of hypopituitarism: a perspective from the Brazilian Society of Endocrinology and Metabolism
ABSTRACT Hypopituitarism is a disorder characterized by insufficient secretion of one or more pituitary hormones. New etiologies of hypopituitarism have been recently described, including head trauma, cerebral hemorrhage, and drug-induced hypophysitis. The investigation of patients with these new disorders, in addition to advances in diagnosis and treatment
Arch. Endocrinol. Metab.. Publicado em: 2021-04
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3. Lipid profile and response to statin therapy in patients with hypopituitarism
ABSTRACT Objective: Dyslipidemia is prevalent among patients with hypopituitarism, especially in those with growth hormone (GH) deficiency. This study aimed to evaluate the response to statin therapy among adult patients with dyslipidemia and hypopituitarism. Subjects and methods: A total of 113 patients with hypopituitarism following up at a neuroendocrin
Arch. Endocrinol. Metab.. Publicado em: 2020-12
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4. Polygenic risk scores and their potential clinical use in psychiatry: are we there yet?
SUMMARY The usual clinical presentation of non-functioning pituitary adenoma (NFPA) consists of symptoms of mass effect and hypopituitarism. NFPA is a rare condition in young women and an uncommon complication during pregnancy. We present the outcome of three patients with NFPA during pregnancy. Case 1: a 38-year-old woman was referred at 32nd week of sponta
Braz. J. Psychiatry. Publicado em: 2020-10
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5. Non-functioning pituitary adenomas and pregnancy: one-center experience and review of the literature
SUMMARY The usual clinical presentation of non-functioning pituitary adenoma (NFPA) consists of symptoms of mass effect and hypopituitarism. NFPA is a rare condition in young women and an uncommon complication during pregnancy. We present the outcome of three patients with NFPA during pregnancy. Case 1: a 38-year-old woman was referred at 32nd week of sponta
Arch. Endocrinol. Metab.. Publicado em: 2020-10
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6. Personalized approach to growth hormone replacement in adults
ABSTRACT Growth hormone (GH) deficiency (GHD) in adults is well-characterized and includes abnormal body composition, reduced bone mass, an adverse cardiovascular risk profile, and impaired quality of life. In the early 1990s, it was also shown that patients with hypopituitarism without GH replacement therapy (GHRT) had excess mortality. Today, GHRT has been
Arch. Endocrinol. Metab.. Publicado em: 10/01/2020
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7. A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism
ABSTRACT Clinically nonfunctioning pituitary adenomas (NFPA) are the most common pituitary tumors after prolactinomas. The absence of clinical symptoms of hormonal hypersecretion can contribute to the late diagnosis of the disease. Thus, the majority of patients seek medical attention for signs and symptoms resulting from mass effect, such as neuro-ophthalmo
Arch. Endocrinol. Metab.. Publicado em: 2016-08
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8. Pituitary metastasis of lung neuroendocrine carcinoma: case report and literature review
SUMMARY Metastasis to the pituitary gland is an unusual situation in clinical practice, but the frequency thereof is increasing due to the increased survival of cancer patients, and greater availability of imaging. In most cases, they are found between the sixth and seventh decades of life, as determined in image examination of patients with known malignant
Arch. Endocrinol. Metab.. Publicado em: 2015-12
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9. Pituitary apoplexy: pathophysiology, diagnosis and management
Pituitary apoplexy is characterized by sudden increase in pituitary gland volume secondary to ischemia and/or necrosis, usually in a pituitary adenoma. Most cases occur during the 5th decade of life, predominantly in males and in previously unknown clinically non-functioning pituitary adenomas. There are some predisposing factors as arterial hypertension, an
Arch. Endocrinol. Metab.. Publicado em: 2015-06
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10. AVALIAÇÃO DAS COMPLICAÇÕES PÓS-OPERATÓRIAS IMEDIATAS DOS PACIENTES SUBMETIDOS À CIRURGIA DE TUMOR DE HIPÓFISE / EVALUATION OF POSTOPERATIVE COMPLICATIONS IMMEDIATE OF PATIENTS UNDERGOING SURGERY OF TUMOR OF PITUITARY
Os adenomas hipofisários são a causa mais comum de massa selar da terceira década em diante, sendo responsável por mais de 10% das neoplasias intracranianas. Estudos recentes apontam para uma prevalência de até 77,6 por 100.000 habitantes. A ressecção cirúrgica pode ser necessária e as complicações pós-operatórias de cirurgia hipofisária inclu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/07/2012
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11. Análise dos genes GHRH e GL12 em pacientes com deficiência de hormônio do crescimento congênita / GHRH and GLI2 genes analysis in patients with congenital growth hormone deficiency
Introduction: Alterations in genes related to GH secretion and pituitary organogenesis have been identified in patients with congenital GH deficiency (GHD). However, in only few cases of GHD the etiology has been established. GH-releasing hormone (GHRH) is an obvious candidate to explain isolated GH deficiency (IGHD). Previous reports in the literature did n
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/02/2012
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12. Expressão dos genes relacionados à apoptose, Bcl-2, bax, e caspase-3 nos adenomas hipofisários clinicamente não funcionantes e seu potencial como marcador do comportamento tumoral / Bcl-2, bax and caspase-3 apoptosis related genes expression in nonfunctioning pituitary adenoma and their role as potential markers of tumor behavior
Pituitary adenomas are benign, slow-growing tumors that arise in the sella turcica and account for 10% to 15% of all intracranial tumors. Non-functioning pituitary adenomas (NFPA) account for around one third of all pituitary adenomas. NFPA do not clinically present as hormonal syndromes and are generally diagnosed as macroadenomas due to marked neurological
Publicado em: 2010