Ic Design
Mostrando 1-12 de 82 artigos, teses e dissertações.
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1. ASSESSMENT OF α-AMYLASE INHIBITION ACTIVITY BY AN OPTIMIZED AND VALIDATED IN VITRO MICROSCALE METHOD
Metabolic disorders, including hyperglycemia, characterize type-2 diabetes. One of the treatment methods used for postprandial hyperglycemia includes using potential therapeutic agents to inhibit α-amylase activity. This study utilized fractional design and the simplex method to optimize in vitro microscale assay inhibition conditions using Miller’s react
Química Nova. Publicado em: 2022
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2. Integrative Approach Based on Simplex-Centroid Design, ESI-MS and Chemometric Analysis for Comprehensive Characterization of Phenolic Compounds from Endopleura uchi Bark
Endopleura uchi (Huber) Cuatrec. is an Amazonian medicinal plant with restricted distribution to the North Region of Brazil. Its bark is commonly used as natural medicines for the treatment of many diseases. Although widely investigated from the phytochemical viewpoint, the knowledge regarding the phenolic content remains unexplored. In order to access the p
J. Braz. Chem. Soc.. Publicado em: 2020-02
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3. Effect of transcranial direct current stimulation on supramaximal intermittent exercise performance
Abstract Aim: Our purpose was to determine whether Transcranial Direct Current Stimulation (tDCS) improves performance in untrained individuals for supramaximal intermittent exercise. Methods: In a cross-over design, 11 healthy male subjects (26.8 ± 4.6 years) performed four Wingate trials after 20 minutes of anodal or sham tDCS over the left Insular Cort
Motriz: rev. educ. fis.. Publicado em: 13/12/2019
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4. Obtaining and characterization of anthocyanins from Euterpe oleracea (açaí) dry extract for nutraceutical and food preparations
Abstract The main constituents of the Euterpe oleracea Mart., Arecaceae, fruits (açaí) are anthocyanins. This paper aimed to standardize the extraction process and characterize an anthocyanin-rich dry extract obtained from this fruit. A 23 full factorial design was used. The volumes of ethanol 92% and acetic acid and the extraction time were used as factor
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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5. Acidentes de trânsito com condutores de veículos: incidência e diferenciais entre motociclistas e motoristas em estudo de base populacional
RESUMO: Objetivos: Estimar incidências de acidentes de trânsito entre condutores de veículos a motor e verificar diferenciais do evento entre as vítimas motociclistas e motoristas de automóvel. Métodos: Foi conduzido um inquérito domiciliar no município de Jequié, Bahia, em 2013, com 1.406 condutores selecionados por amostragem por conglomerado.
Rev. bras. epidemiol.. Publicado em: 05/12/2019
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6. Menor performance das funções executivas prediz maior consumo de álcool e tabaco em adolescentes
RESUMO Objetivo O estudo propôs-se a avaliar diferentes domínios das funções executivas em adolescentes como preditores ao uso de álcool e cigarro. Métodos Utilizou-se um delineamento transversal. A amostra foi composta por 239 adolescentes com idade média de 15,34 (±2,32). Os testes Alcohol Use Disorders Identification Test (AUDIT) e Fagerstrom
J. bras. psiquiatr.. Publicado em: 21/10/2019
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7. Mortalidad por olas de calor en la ciudad de Buenos Aires, Argentina (2005-2015)
Resumo: O objetivo deste trabalho é analisar a mortalidade durante as ondas de calor na cidade de Buenos Aires, Argentina, no período de 2005-2015. Foi usado um desenho de séries temporais com modelos aditivos generalizados, vinculando a mortalidade com dias de onda de calor em todo o período, e com dias da onda de calor em 2013, a mais prolongada desde
Cad. Saúde Pública. Publicado em: 09/09/2019
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8. Prevalence of Systemic Arterial Hypertension in Quilombola Communities, State of Sergipe, Brazil
Resumo Fundamento: Os quilombolas são grupos formados por indivíduos com ancestralidade negra, inseridos em um contexto de vulnerabilidade social devido ao baixo nível socioeconômico, influenciando assistência à saúde e desenvolvimento de doenças crônicas. Objetivo: Avaliar a prevalência da hipertensão arterial sistêmica e sua associação a fa
Arq. Bras. Cardiol.. Publicado em: 15/08/2019
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9. Design, Synthesis, Trypanocidal Activity, and Studies on Human Album in Interaction of Novel S-Alkyl-1,2,4-triazoles
Chagas disease is a neglected tropical disease caused by the hemoflagellated parasite Trypanosoma cruzi (Kinetoplastida). The only available drug to treat chagasic patients in Brazil, the nitroheterocycle benznidazole, is effective solely during the acute phase of the infection. There is accordingly a need to develop new therapeutic tools for the treatment o
J. Braz. Chem. Soc.. Publicado em: 04/07/2019
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10. Antibiotic prophylaxis prior to urodynamic study in patients with traumatic spinal cord injury. Is there an indication?
ABSTRACT Study design: Retrospective cohort of patients with traumatic spinal cord injury (SCI) that have been hospitalized for physical-functional rehabilitation purposes. Objectives: To compare the incidence of urinary tract infection (UTI) after urodynamic study (UDS) in three hospitals that adopted different protocols with regard to the preparation of
Int. braz j urol.. Publicado em: 27/05/2019
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11. Activity of the antiarrhythmic drug amiodarone against Leishmania (L.) infantum: an in vitro and in vivo approach
Abstract Background: Considering the high toxicity and limited therapies available for treating visceral leishmaniasis (VL), the drug repositioning approach represents a faster way to deliver new therapies to the market. Methods: In this study, we described for the first time the activity of a potent antiarrhythmic, amiodarone (AMD), against L. (L.)infantu
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 29/11/2018
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12. Synthesis and Antimicrobial Activity of Glycosylated 2-Aryl-5-amidinobenzimidazoles
A series of new glycosylated 2-aryl-5-amidinobenzimidazoles derived from four different carbohydrates (D-glucose, D-galactose, N-acetyl-D-glucosamine and lactose) were synthesized by the condensation of the appropriate 4-formyl-3-methoxyphenyl glycoside with 4-amidino- or 4-N-isopropylamidino-ortho-phenylenediamine hydrochloride. All the compounds were prope
J. Braz. Chem. Soc.. Publicado em: 2018-06