Immunity Modulation
Mostrando 1-12 de 104 artigos, teses e dissertações.
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1. Bromelain: Methods of Extraction, Purification and Therapeutic Applications
Bromelain is a concoction of sulfhydryl proteolytic enzymes. Depending upon the site of extraction it can be regarded as either stem bromelain (SBM) (EC 3.4.22.32) or fruit bromelain (FBM) (EC 3.4.22.33). Bromelain remain enzymatic active over a broad spectrumand endure a range of pH (5.5 to 8.0) and temperature (35.5 to 71 ºC). It is one of the extensively
Braz. arch. biol. technol.. Publicado em: 06/05/2016
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2. Septic arthritis: immunopathogenesis, experimental models and therapy
Septic arthritis is an inflammatory disease of the joints that is started by an infection whose most common agent is Staphylococcus aureus. In this review we discuss some of the most arthritogenic bacterial factors and the contribution of innate and specific immune mechanisms to joint destruction. Special emphasis is given to the induction of experimental
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 06/06/2014
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3. Prebiotic inulin: Useful dietary adjuncts to manipulate the livestock gut microflora
In recent years, there has been a growing appreciation on the relevance of gastrointestinal microflora in both ruminants and non-ruminants owing to revelation of their role in several physiological functions including digestion, nutrient utilization, pathogen exclusion, gastrointestinal development, immunity system, gut gene expression and quality of animal
Braz. J. Microbiol.. Publicado em: 07/05/2013
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4. A infecção por Leishmania infantum chagasi altera o metabolismo lipídico do hospedeiro
American visceral leishmaniasis (AVL), caused by Leishmania infantum chagasi (L.i.chagasi), stands as a public health problem in Brazil, with human and canine cases related in all states..Lipid metabolism can be modified in several status of infection. For example, experimental studies show that the cholesterol is necessary to internalization and replication
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/12/2012
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5. O papel modulador do receptor símile a TOLL 2 (TLR2) e da microbiota intestinal na sensibilidade e sinalização da insulina em camundongos / The modulatory role of the Toll-like receptor (TLR)2 and of the gut microbiota in the modulation of the insulin sensitivity and signaling
Environmental factors and host genetics interact to control the gut microbiota, which may have a role in the development of obesity and insulin resistance. TLR2 deficient mice, under germ-free conditions are protected from diet-induced insulin resistance. Diet-induced obese mice, acutely treated with TLR2 oligonucleotide antisense during 4 days showed increa
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/02/2012
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6. Analysis of the expression of toll-like receptors 2 and 4 and cytokine production during experimental Leishmania chagasi infection
Toll-like receptors (TLRs) recognise pathogen-derived molecules and influence immunity to control parasite infections. This study aimed to evaluate the mRNA expression of TLRs 2 and 4, the expression and production of the cytokines interleukin (IL)-12, interferon (IFN)-γ, tumor necrosis factor (TNF)-α, IL-17, IL-10 and transforming growth factor (TGF)-β a
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-08
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7. Modulação de eventos da imunidade humoral e celular por venenos brutos e componentes dos venenos de Bothrops jararacussu e Bothrops pirajai / Modulation of events of humoral and cellular immunity by crude venom and components of Bothrops jararacussu and Bothrops pirajai
Snakes of the genus Bothrops are responsible for 90% of snakebites in Brazil. Their venoms cause local effects in humans and animals, such as hemorrhage, edema, pain and necrosis, characteristic of an inflammatory response. The mechanism is not well defined. These effects are related to the combined action of proteases, substances that induce bleeding and ph
Publicado em: 2010
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8. Treatment of hemorrhagic shock with hypertonic saline solution modulates the inflammatory response to live bacteria in lungs
Shock and resuscitation render patients more susceptible to acute lung injury due to an exacerbated immune response to subsequent inflammatory stimuli. To study the role of innate immunity in this situation, we investigated acute lung injury in an experimental model of ischemia-reperfusion (I-R) followed by an early challenge with live bacteria. Conscious ra
Brazilian Journal of Medical and Biological Research. Publicado em: 04/09/2009
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9. Immune response modulation in chicken immunized with vaccines associated to b-Glucan. / Modulação da resposta imune em aves imunizadas com vacinas aviárias associadas ao b-glucano.
Os b-glucanos são formados por polissacarídeos estruturais da parede celular de leveduras (Saccharomyces cerevisiae), alguns cereais em grãos e fungos. Os b-glucanos apresentam a molécula de glicose ligada ao carbono nas posições b-1,3 e pode apresentar cadeias laterais com o resíduo de glicose ligado nas posições b-1,6. O b-glucano tem sua ação b
Publicado em: 2009
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10. Role of B-1 cell in inflammatory response to lipopolysaccharid / Participação da célula B-1 na resposta inflamatória ao lipopolissacáride
Sepsis syndrome is caused by inappropriate immune activation due to bacteria and bacterial components released during infection. This syndrome is the leading cause of death in intensive care units. Specialized B-lymphocytes located in the peritoneal and pleural cavities are known as B-1 cells. These cells produce IgM and IL-10, both of which are potent regul
Publicado em: 2009
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11. Influence of the use of alternative additives instead of antimicrobials on the performance, intestinal morphology and immunity of broilers / Influência do uso de aditivos alternativos a antimicrobianos sobre o desempenho, morfologia intestinal e imunidade de frangos de corte
Due to the public health concerning with the use of antimicrobials as growth promoters in livestock, the number of researches of alternative strategies for antimicrobials has increased. Some researches about the use of prebiotics and probiotics as additives have demonstrated that those promote the beneficial modulation of the intestinal microbiota and have i
Publicado em: 2008
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12. Toll-like receptor 4 (TLR4) na modulação da imunidade do tipo 2. / Toll-like receptor 4 (TLR4) and modulation of Th2 immunity.
Epidemiological and experimental data suggest that bacterial lipopolysaccharides (LPS) can either protect from or exacerbate allergic asthma. LPS triggers immune responses through Toll-like receptor (TLR) 4 that in turn activates two major signaling pathways via either MyD88 or TRIF adaptor proteins. LPS is a pro-Th1 adjuvant while aluminum hydroxide (Alum)
Publicado em: 2008