Invasin
Mostrando 1-12 de 80 artigos, teses e dissertações.
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1. Evaluation of the role of Mycobacterium tuberculosis pili (MTP) as an adhesin, invasin, and cytokine inducer of epithelial cells
Abstract This study was undertaken in order to assess the involvement of Mycobacterium tuberculosis pili (MTP) as an adhesin, invasin, and cytokine inducer in the M. tuberculosis-epithelial cell interaction. A MTP-deficient strain of M. tuberculosis demonstrated a significant reduction of 69.39% (p = 0.047) and 56.20% (p = 0.033) in its ability to adhere to
Braz J Infect Dis. Publicado em: 2016-04
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2. Invasin
gimB found in a bovine intestinalEscherichia coli with an adherent and invasive profileThe invasin
gimB (genetic island associated with human newborn meningitis) is usually found in ExPEC (Extraintestinal PathogenicEscherichia coli ) such as UPEC (uropathogenicE. coli ), NMEC (neonatal meningitisE. coli ) and APEC (avian pathogenicE. coli ). In NMEC,Braz. J. Microbiol.. Publicado em: 2015-09
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3. Human sepsis-associated Escherichia coli (SEPEC) is able to adhere to and invade kidney epithelial cells in culture
The adhesins of extraintestinal pathogenic Escherichia coli are essential for mediating direct interactions between the microbes and the host cell surfaces that they infect. Using fluorescence microscopy and gentamycin protection assays, we observed that 49 sepsis-associated E. coli (SEPEC) strains isolated from human adults adhered to and invaded Vero cells
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-05
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4. Papel das hemaglutininas 67-72p de Corynebacterium diphtheriae na ligação a proteínas plasmáticas, superfícies celulares, invasão e indução de apoptose / Participation of hemagglutinin 67-72p of corynebacterium diphtheriae in binding to plasma proteins, cells surfaces, invasion and induction of apoptosis
Corynebacterium diphtheriae pode ser isolado tanto de quadros de difteria clássica, quanto de infecções sistêmicas, como endocardite. O fibrinogênio (Fbn) e a fibronectina (Fn) são glicoproteínas presentes na matriz extracelular de tecidos conjuntivos. A influência destas proteínas na patogênese das infecções locais e invasivas causadas por C. di
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/06/2010
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5. Formação de biofilme em amostras de Escherichia coli associada a sepse (SEPEC) : caracterização fenotipica, genotipica e filogenia / Biofilm formation by sepsis associated Escherichia coli (SEPEC) strains : genotypic, phenotypic characterization and phylogeny
Extraintestinal Pathogenic Escherichia coli (ExPEC) form a heterogeneous group as the bacterial virulence factors involved in its pathogenicity and local infection in the host. Our work aimed study the phenotypic and genotypic characteristics of biofilm formation and phylogeny of sepsis-associated Escherichia coli Human (SEPEC), as well as their patterns of
Publicado em: 2010
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6. Production and characterization of monoclonal antibodies against the identical region of LigA and LigB proteins from Leptospira interrogans / Produção e caracterização de anticorpos monoclonais contra a região idêntica das proteínas LigA e LigB de Leptospira interrogans
Leptospirosis is a zoonotic disease caused by pathogenic bacteria belonging to the Leptospira genus. Several mammals may carry the agent, and rats are the most important source of human infection in urban settings. The wide spectrum of clinical manifestations varies from mild cases, with fever and headaches, to severe presentations, with liver and kidney fai
Publicado em: 2009
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7. Identification of the integrin binding domain of the Yersinia pseudotuberculosis invasin protein.
The invasin protein of the pathogenic Yersinia pseudotuberculosis mediates entry of the bacterium into cultured mammalian cells by binding several beta 1 chain integrins. In this study, we identified the region of invasin responsible for cell recognition. Thirty-two monoclonal antibodies directed against invasin were isolated, and of those, six blocked cell
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8. Cultured mammalian cells attach to the invasin protein of Yersinia pseudotuberculosis.
The expression of invasin, the product of the Yersinia pseudotuberculosis inv gene, allows enteric bacteria to enter cultured mammalian cells. The ability of invasin to bind animal cells and the potential significance of this interaction in the entry process were investigated. It was found that HEp-2 cells could attach to surfaces coated with bacterial membr
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9. An Immunoglobulin Superfamily-Like Domain Unique to the Yersinia pseudotuberculosis Invasin Protein Is Required for Stimulation of Bacterial Uptake via Integrin Receptors
The binding of the Yersinia pseudotuberculosis and Yersinia enterocolitica invasin proteins to β1 integrin receptors allows internalization of these organisms by cultured cells. The C-terminal 192-residue superdomain of the Y. pseudotuberculosis invasin is necessary and sufficient for integrin recognition, while a region located outside, and N-terminal to,
American Society for Microbiology.
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10. Mapping and topographic localization of epitopes of the Yersinia pseudotuberculosis invasin protein.
The Yersinia pseudotuberculosis invasin protein is a 986-amino-acid outer membrane protein that promotes bacterial penetration into mammalian cells by binding to beta 1-chain integrin receptors. We previously showed that the integrin binding domain is encoded by the carboxyl-terminal 192 amino acids. To further investigate the structure of this protein, we c
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11. The integrin-binding domain of invasin is sufficient to allow bacterial entry into mammalian cells.
Yersinia pseudotuberculosis is able to enter normally nonphagocytic host cells by multiple pathways, the most efficient of which is mediated by invasin, a 986-amino-acid bacterial outer membrane protein. It has previously been shown that the C-terminal 192 amino acids of invasin are sufficient to bind mammalian cells. To determine if additional regions of th
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12. Involvement of focal adhesion kinase in invasin-mediated uptake
High-efficiency entry of the enteropathogenic bacterium Yersinia pseudotuberculosis into nonphagocytic cells is mediated by the bacterial outer membrane protein invasin. Invasin-mediated uptake requires high affinity binding of invasin to multiple β1 chain integrin receptors on the host eukaryotic cell. Previous studies using inhibitors have indicated that
The National Academy of Sciences.