Leishmania Plants
Mostrando 1-12 de 37 artigos, teses e dissertações.
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1. ANTIPROMASTIGOTE AND CYTOTOXIC ACTIVITIES OF FLAVONOIDS FROM Fridericia speciosa LEAVES
Fridericia speciosa (Bignoniaceae) is a liana that occurs in humid to dry vegetation in eastern and southeastern Brazil. Species belonging to the genus Fridericia are employed as medicinal plants. This study evaluates the antipromastigote and cytotoxic activities of the crude extract, fractions, and compounds isolated from F. speciosa, and an HPLC (High-Perf
Quím. Nova. Publicado em: 2020-12
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2. Leishmanicidal compounds of Nectria pseudotrichia, an endophytic fungus isolated from the plant Caesalpinia echinata (Brazilwood)
BACKGROUND In a screen of extracts from plants and fungi to detect antileishmanial activity, we found that the ethyl acetate extract of the fungus Nectria pseudotrichia, isolated from the tree Caesalpinia echinata (Brazilwood), is a promising source of bioactive compounds. OBJECTIVES The aims of this study were to isolate and determine the chemical structu
Mem. Inst. Oswaldo Cruz. Publicado em: 2018-02
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3. Evaluation of the antiplasmodial and leishmanicidal potential of Myrciaria dubia (Myrtaceae) extract
Abstract INTRODUCTION: Malaria and leishmaniasis are prevalent in tropical regions, which have environmental characteristics that are highly favorable to protozoa and vectors of these diseases; the transmission of these infections in sub-tropical regions, although recognized, represents only a small fraction of cases. Plants are constantly being used in the
Rev. Soc. Bras. Med. Trop.. Publicado em: 2016-10
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4. Induction of apoptosis by zerumbone isolated from Zingiber zerumbet (L.) Smith in protozoan parasite Leishmania donovani due to oxidative stress
Abstract In the present context of emergence of resistance aligned with the conventional anti-leishmanial drugs and occasional treatment failure compelled us to continue the search for replaceable therapeutic leads against Leishmaniainfection. Various ginger spices of the Zingiberaceae family are widely used as spices, flavouring agents, and medicines in Sou
Braz J Infect Dis. Publicado em: 2016-02
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5. Antileishmanial activity of the essential oil from Tetradenia riparia obtained in different seasons
The herbaceous shrub Tetradenia riparia has been traditionally used to treat inflammatory and infectious diseases. Recently, a study showed that T. riparia essential oil (TrEO) obtained in summer has antileishmanial effects, although these results could be influenced by seasonal variation. This study evaluated the activity of the TrEO obtained in different s
Mem. Inst. Oswaldo Cruz. Publicado em: 24/11/2015
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6. Antileishmanial activity of some Brazilian plants, with particular reference to Casearia sylvestris
As leishmanioses são um complexo de doenças causadas por protozoários Leishmania, cujo tratamento é restrito a um número limitado de fármacos que apresentam toxicidade elevada, efeitos colaterais e geralmente custos elevados. Existe uma enorme variedade de plantas tropicais distribuídas no Brasil e para muitas pessoas pobres a terapia para várias doe
An. Acad. Bras. Ciênc.. Publicado em: 09/06/2015
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7. Therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products
This study examined whether the antidermatophytic activity of essential oils (EOs) can be used as an indicator for the discovery of active natural products against Leishmania amazonensis. The aerial parts of seven plants were hydrodistilled. Using broth microdilution techniques, the obtained EOs were tested against three strains of dermatophytes (Trichophyto
Mem. Inst. Oswaldo Cruz. Publicado em: 13/02/2015
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8. Actin expression in trypanosomatids (Euglenozoa: Kinetoplastea)
Heteroxenic and monoxenic trypanosomatids were screened for the presence of actin using a mouse polyclonal antibody produced against the entire sequence of the Trypanosoma cruzi actin gene, encoding a 41.9 kDa protein. Western blot analysis showed that this antibody reacted with a polypeptide of approximately 42 kDa in the whole-cell lysates of parasites tar
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-08
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9. Bioprospecção de plantas com potencial farmacológico para o tratamento das leishmanioses / Bioprospecting of plants with pharmacological potential for the treatment of leishmaniasis.
As leishmanioses são doenças causadas por protozoários do gênero Leishmania que acometem milhões de pessoas em todo o mundo. Apresentam manifestações clínicas que variam de lesões cutâneas, mucocutâneas a forma visceral, geralmente fatal. Antimoniais pentavalentes são as drogas de primeira escolha para o tratamento das leishmanioses, porém são
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/08/2011
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10. Leishmanicidal, trypanocidal, and cytotoxic activities of endophytic fungi associated with bioactive plants in Brazil
One hundred and twenty-one isolates of endophytic fungi were recovered from leaves of the bioactive Brazilian plant species Ageratum myriadenia, Palicourea tetraphylla, Piptadenia adiantoides, and Trixis vauthieri. All fungal isolates were cultivated in liquid media and crude extracts were obtained with ethyl acetate. The crude extracts were tested in bioass
Brazilian Journal of Microbiology. Publicado em: 2010-06
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11. Chemistry, cytotoxicity and antileishmanial activity of the essential oil from Piper auritum
Leishmaniasis is one of the most important parasitic infections, but current treatments are unsatisfactory due to their toxicity, cost and resistance. Therefore, the development of new antileishmanial compounds is imperative. Many people who live in endemic areas use plants as an alternative to treat the disease. In this paper, we characterised the essential
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-03
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12. Chemical composition and antiprotozoal activities of Colombian Lippia spp essential oils and their major components
The chemical composition and biological activities of 19 essential oils and seven of their major components were tested against free and intracellular forms of Leishmania chagasi and Trypanosoma cruzi parasites as well as Vero and THP-1 mammalian cell lines. The essential oils were obtained from different species of Lippia, a widely distributed genus of Colo
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-03