Lignans
Mostrando 1-12 de 42 artigos, teses e dissertações.
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1. Protective effect of Schisandra chinensis total lignans on acute alcoholic-induced liver injury related to inhibiting CYP2E1 activation and activating the Nrf2/ARE signaling pathway
ABSTRACT Schisandra chinensis (Turcz.) Baill., Schisandraceae, is a well-known traditional Chinese medicine used mainly as a recipe for hepatoprotection. Modern researches have revealed that the hepatoprotection is related to its lignans and crude polysaccharide. In this study, we examined the effect and mechanism of S. chinensis total lignans on the liver i
Rev. bras. farmacogn.. Publicado em: 27/05/2019
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2. Flavonol Tri-O-glycoside and Other Chemical Constituents from Flowers of Aristolochia trulliformis
A new flavonol triglycoside, named kaempferol-3-O-β-D-glucopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside, was isolated from flowers of Aristolochia trulliformis (Aristolochiaceae) together with 15 known compounds, including six flavonoids and four lignans. The structures of the compounds were determined by spectroscopic analyses, inclu
J. Braz. Chem. Soc.. Publicado em: 08/04/2019
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3. Chemical constituents from ethanol extract of Polyalthia rumphii branches and their cytotoxicity evaluation
ABSTRACT Twelve known compounds, including eight alkaloids, three lignans and one gossypol derivative, were isolated from the branches of Polyalthia rumphii (Blume ex Hensch.) Merr., Annonaceae. The chemical structures were determined by spectroscopic methods and comparison with literature data. All the isolates were evaluated the cytotoxicity against three
Rev. bras. farmacogn.. Publicado em: 2018-04
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4. CHEMICAL CONSTITUENTS FROM THE STEM BARK OF
Annona pickelii (Annonaceae)The phytochemical investigation of the stem bark of
Annona pickelii yielded four steroids (β-sitostenone, β-sitosterol, stigmasterol and campesterol), three lignans (eudesmin, magnolin and yangambin), twelve alkaloids (liriodenine, lysicamine, atherospermidine, anonaine, analobine, asimilobine, discretamine, stepholidine, coclaurine, orQuím. Nova. Publicado em: 2015-07
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5. Application of the Negishi reaction in the synthesis of thiophene-based lignans analogues with leishmanicidal effects
As lignanas tetraidrofurânicas são metabólitos secundários com reconhecida atividade antiprotozoária. Na literatura, há vários relatos sobre os efeitos anti-parasitários de análogos sintéticos de lignanas contendo pontes de enxofre. Neste trabalho, foi realizada a síntese de análogos tiofênicos de lignanas com o uso de uma estratégia sintética
J. Braz. Chem. Soc.. Publicado em: 2014-10
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6. Identification and characterisation of phenolic compounds extracted from Moroccan olive mill wastewater
Olive mill wastewater, hereafter noted as OMWW was tested for its composition in phenolic compounds according to geographical areas of olive tree, i.e. the plain and the mountainous areas of Tadla-Azilal region (central Morocco). Biophenols extraction with ethyl acetate was efficient and the phenolic extract from the mountainous areas had the highest concent
Food Sci. Technol. Publicado em: 2014-06
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7. Intraspecific variability of Holostylis reniformis: concentration of lignans, as determined by maceration and supercritical fluid extraction (SFE-CO2), as a function of plant provenance and plant parts
Maceration and supercritical fluid extraction were used to prepare extracts from parts of plants (Holostylis reniformis) collected in two different regions of Brazil. ¹H NMR, HPLC-DAD-ESI/MS, HPLC-DAD, GC-MS, and chemometric techniques were used to analyse lignans in the extracts and showed that yields of SFE-CO2 were less than or equal to those of hexane m
Quím. Nova. Publicado em: 2014-04
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8. Novel bioactive dibenzocyclooctadiene lignans from Schisandra neglecta
Quatro novas dibenzociclooctadienolignanas, neglectalignanas A-D (1-4), juntamente com dezenove compostos conhecidos (5-23), foram isolados das hastes de Schisandra neglecta. Suas estruturas e esteroquímicas foram elucidadas por métodos espectroscópicos, incluindo as técnicas de ressonância magnética nuclear (RMN) de 1D e 2D, e espectrometria de massas
J. Braz. Chem. Soc.. Publicado em: 2013-12
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9. Constituintes químicos de Solanum buddleifolium Sendtn
The chemical investigation of the stem EtOH extract of S. buddleifolium resulted in the isolation of terpenoids, amides, lignans and a steroidal alkaloid. Based on HRMS, IR and ¹H and 13C NMR data analysis, the structures of the isolated compounds were identified as: 13-hydroxysolavetivone, betulinic acid, N-trans-caffeoyltyramine, N-trans-feruloyldopamine,
Quím. Nova. Publicado em: 2013
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10. Uma nova lignana e outros constituintes químicos de Hypenia salzmannii (Benth.) Harley (Lamiaceae) / A novel lignan and other chemical constituents from Hypenia salzmannii (Benth.) Harley (Lamiaceae).
A família Lamiaceae possui 7.193 espécies distribuidas em aproximadamente 260 gêneros que ocorrem na forma de ervas, arbustos e árvores distribuídos em ambos os hemisférios e inclui um grande número de plantas medicinais de importância significativa. No Brasil ocorrem aproximadamente de 26 gêneros e 350 espécies. O gênero Hypenia (Mart. ex Benth)
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/02/2012
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11. Evaluation of larvicidal activity of the methanolic extracts of Piper alatabaccum branches and P. tuberculatum leaves and compounds isolated against Anopheles darlingi
Piper is a notable genus among Piperaceae due to their secondary metabolites such as lignans, amides, esters and long chain fatty acids used as anti-herbivore defenses with comparable effects of pyrethroids, that holds a promise in insect control, including malaria vectors such as Anopheles darlingi, the main vector in the North of Brazil. Methanolic extract
Rev. bras. farmacogn.. Publicado em: 03/04/2012
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12. Aspectos estruturais de algumas neolignanas hidrobenzofurânicas
The neolignans are defined as dimers of allylphenol and propenylphenol between itself or crossed, whose bond does not occur by the 8-8' carbons like lignans. This review centered on stereochemical aspects of the hydrobenzofuran type, a widespread skeleton among neolignans. The chemical structures established based on spectrometric data are registered in the
Quím. Nova. Publicado em: 2012