Lipc Polymorphisms
Mostrando 1-3 de 3 artigos, teses e dissertações.
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1. Análise da influência de polimorfismos presentes nos genes APO B, CETP, LPL e LIPC em uma população dislipidêmica do Rio Grande do Sul
Dislipidemia é uma desordem multifatorial causada pela interação entre fatores ambientais e genéticos. A identificação dos componentes genéticos responsáveis por essas características tem sido intensamente investigada nos últimos anos. Esses estudos têm enfocado principalmente polimorfismos nos genes que codificam proteínas estruturais e enzimas
Publicado em: 2008
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2. Association of variation in hepatic lipase activity with promoter variation in the hepatic lipase gene. The LOCAT Study Invsestigators.
The associations between six genetic polymorphisms in the hepatic lipase (HL) gene (LIPC) and variation in postheparin HL activity and fasting serum lipoproteins were evaluated in 395 male Finnish coronary heart disease patients with HDL cholesterol concentrations
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3. A hepatic lipase (LIPC) allele associated with high plasma concentrations of high density lipoprotein cholesterol
Genetic factors strongly influence interindividual variation in plasma high density lipoprotein cholesterol (HDL-C) levels, but the specific genetic polymorphisms that confer heritable variation in HDL-C levels have not been identified. In this study we examined the relationship between polymorphism in LIPC, the gene encoding hepatic lipase, and plasma HDL-C
The National Academy of Sciences of the USA.