Lipofuscin
Mostrando 1-12 de 59 artigos, teses e dissertações.
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1. Kidney anatomy, histology and histometric traits associated to renosomatic index in Gymnotus inaequilabiatus (Gymnotiformes: Gymnotidae)
RESUMO Gymnotus inaequilabiatus é um peixe neotropical amplamente distribuído em áreas marginais de baías. O objetivo deste estudo foi descrever características anatômicas, histológicas e histopatológicas no rim cefálico e exócrino. Análises histométricas e a densidade volumétrica estrutural foram associadas ao índice renossomático (IRS). Frag
Neotrop. ichthyol.. Publicado em: 25/11/2019
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2. A compilation of longevity data in decapod crustaceans
Abstract Longevity information was collected from 219 literature sources for 244 decapod crustaceans, representing 1.7% of species, 4.8% of genera and 30% of families. Reliable methods of age determination (laboratory rearing, mark-recapture method, growth models, lipofuscin method) revealed longevities from 0.1 to 72 years, corresponding to a 700-fold diffe
Nauplius. Publicado em: 16/09/2019
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3. Xanthine oxidase activity in patients with age-related cataract associated with hypertension
Reactive oxygen species and lipid peroxidation are important factors that contribute to the development of age-related cataract. The study included 130 patients with age-related cataract, 69 of whom were diagnosed with hypertension (HT), 20 with hypertension and type 2 diabetes mellitus (DM), and 41 had no accompanying condition. The following parameters wer
Braz J Med Biol Res. Publicado em: 26/03/2018
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4. Effect of the tocotrienol-rich fraction on the lifespan and oxidative biomarkers in Caenorhabditis elegans under oxidative stress
OBJECTIVE: This study was performed to determine the effect of the tocotrienol-rich fraction on the lifespan and oxidative status of C. elegans under oxidative stress. METHOD: Lifespan was determined by counting the number of surviving nematodes daily under a dissecting microscope after treatment with hydrogen peroxide and the tocotrienol-rich fraction. T
Clinics. Publicado em: 2013-05
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5. Estudo dos grânulos de lipofucsina e das sinapses do córtex temporal durante o envelhecimento / Study of lipofuscin granules and synapses in the temporal cortex during aging.
Alterações morfológicas e funcionais ocorrem durante o envelhecimento, período da vida com maior incidência de doenças neurodegenerativas. No presente trabalho acompanhou-se a evolução dos grânulos de lipofucsina durante o envelhecimento para investigar alterações sinápticas, assim como proteínas associadas com doenças neurodegenerativas (alfa-
Publicado em: 2011
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6. Myocardial fibrosis prevention and accumulation of lipofuscin in myocities cardiac of mdx mice / Prevenção da fibrose miocardica e acumulo de lipofuscina em cardiomiocitos de camundongos mdx
The Duchenne Muscle Dystrophy is a progressive myopathy caused by recessive autossomic disease connected to the gender, which attacks male kids, and involves to motor disability in the property, leading to death around the second decade of life. It is caused by an alteration in the codifier gene of the protein dystropin, which maintains the integrity of the
Publicado em: 2009
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7. Involvement of the tyrosinase gene in the deposition of cardiac lipofuscin in mice. Association with aortic fatty streak development.
Lipofuscin pigment, a terminal oxidation product, accumulates within cells during the normal aging process and under certain pathological conditions. We have analyzed a genetic cross between two inbred mouse strains, BALB/cJ and a subline of C57BL/6J, which differ in lipofuscin deposition. A comparison of the segregation pattern of cardiac lipofuscin with th
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8. Spectroscopic and morphological studies of human retinal lipofuscin granules
The emission properties of ocular lipofuscin granules isolated from human retinal pigment epithelial cells are examined by using steady-state fluorescence spectroscopy and spectrally resolved confocal microscopy. The shape of the emission spectrum of a thick sample of lipofuscin granules dried on glass varies with excitation energy. The polarization of this
The National Academy of Sciences.
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9. Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration
Recessive Stargardt's macular degeneration is an inherited blinding disease of children caused by mutations in the ABCR gene. The primary pathologic defect in Stargardt's disease is accumulation of toxic lipofuscin pigments such as N-retinylidene-N-retinylethanolamine (A2E) in cells of the retinal pigment epithelium. This accumulation appears to be responsib
The National Academy of Sciences.
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10. Portal lymphadenopathy associated with lipofuscin in chronic cholestatic liver disease.
To determine whether portal lymphadenopathy in primary biliary cirrhosis is caused by deposition of lipofuscin pigment in sinus histiocytes and to compare primary biliary cirrhosis with other liver diseases a retrospective study on a consecutive series of 169 livers obtained at transplantation was carried out. There were grouped into eight diagnostic categor
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11. Fluorescence in Best's vitelliform dystrophy, lipofuscin, and fundus flavimaculatus.
Control photographs, with the Baird Atomic B4 and B5 filters in place prior to fluorescein injection, show exposure of the film corresponding to (1) the small yellow vitelliform lesions at the edge of a disrupted disc, (2) the pseudohpopyon in a vitelliform cyst, (3) orange lipofuscin overlying a malignant melanoma, and (4) some of the flecks in a case of fu
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12. Rpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E
There is a growing body of evidence that the nondegradable fluorophores that accumulate as the lipofuscin of retinal pigment epithelium (RPE) are involved in mechanisms leading to the degeneration of RPE in macular degeneration. Most of the constituents of RPE lipofuscin are inadvertent products of the retinoid visual cycle, the enzymatic pathway by which th
National Academy of Sciences.