Membrane Fluidity
Mostrando 1-12 de 230 artigos, teses e dissertações.
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1. Compatibility of GROMOS-Derived Atomic Parameters for Lipopolysaccharide Membranes with the SPC/E Water Model and Alternative Long-Range Electrostatic Treatments Using Single Nonbonded Cutoff and Atom-Based Charge Schemes
Recent developments of GROMACS v.2016 ceased to support methodological approaches used in the development and validation of the GROMOS force field. We investigated the performance of a previously developed extension of the GROMOS force field for lipopolysaccharides to reproduce the structural dynamics of bacterial outer membrane (OM) using a single cutoff fo
J. Braz. Chem. Soc.. Publicado em: 21/10/2019
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2. Bioactivity and action mechanism of green propolis against Pythium aphanidermatum
Abstract: We have established how natural compounds from green propolis collected by the species Apis mellifera act against the growth of Pythium aphanidermatum. On the basis of mass spectrometry (Q-ToF MS), we determined that Artepillin C, the major constituent of green propolis, underlies the effect and displays activity against P. aphanidermatum at a mini
An. Acad. Bras. Ciênc.. Publicado em: 01/07/2019
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3. CspB of an arctic bacterium, Polaribacter irgensii KOPRI 22228, confers extraordinary freeze-tolerance
ABSTRACT Freezing temperatures are a major challenge for life at the poles. Decreased membrane fluidity, uninvited secondary structure formation in nucleic acids, and protein cold-denaturation all occur at cold temperatures. Organisms adapted to polar regions possess distinct mechanisms that enable them to survive in extremely cold environments. Among the co
Braz. J. Microbiol.. Publicado em: 2018-03
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4. Antioxidant effect of 4-nerolidylcatechol and α-tocopherol in erythrocyte ghost membranes and phospholipid bilayers
4-Nerolidylcatechol (4-NC) is found in Pothomorphe umbellataroot extracts and is reported to have a topical protective effect against UVB radiation-induced skin damage, toxicity in melanoma cell lines, and antimalarial activity. We report a comparative study of the antioxidant activity of 4-NC and α-tocopherol against lipid peroxidation initiated by two fre
Braz J Med Biol Res. Publicado em: 06/09/2013
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5. Electron paramagnetic resonance study of lipid and protein membrane components of erythrocytes oxidized with hydrogen peroxide
Electron paramagnetic resonance (EPR) spectroscopy of spin labels was used to monitor membrane dynamic changes in erythrocytes subjected to oxidative stress with hydrogen peroxide (H2O2). The lipid spin label, 5-doxyl stearic acid, responded to dramatic reductions in membrane fluidity, which was correlated with increases in the protein content of the membran
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-06
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6. Growth, fatty acid profile in major lipid classes and lipid fluidity of Aurantiochytrium mangrovei Sk-02 as a function of growth temperature
Aurantiochytrium mangrovei Sk-02 was grown in a medium containing glucose (40 g/l), yeast extract (10 g/L) and sea salts (15 g/L) at temperatures ranging from 12 to 35°C. The fastest growth (µmax= 0.15 h-1) and highest fatty acid content of 415 mg/g-dry cell weight were found in the cells grown at 30°C. However, the cells grown at 12°C showed the highest
Brazilian Journal of Microbiology. Publicado em: 2012-03
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7. Effect of silybin on high-fat-induced fatty liver in rats
Silybin, a natural antioxidant, has been traditionally used against a variety of liver ailments. To investigate its effect and the underlying mechanisms of action on non-alcoholic fatty liver in rats, we used 60 4-6-week-old male Sprague-Dawley rats to establish fatty liver models by feeding a high-fat diet for 6 weeks. Hepatic enzyme, serum lipid levels, ox
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-07
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8. In vivo and in vitro effect of imipramine and fluoxetine on Na+, K+-ATPase activity in synaptic plasma membranes from the cerebral cortex of rats
The effects of in vivo chronic treatment and in vitro addition of imipramine, a tricyclic antidepressant, or fluoxetine, a selective serotonin reuptake inhibitor, on the cortical membrane-bound Na+,K+- ATPase activity were studied. Adult Wistar rats received daily intraperitoneal injections of 10 mg/kg of imipramine or fluoxetine for 14 days. Twelve hours af
Publicado em: 2010
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9. Efeito da adição de Glutationa na função e estresse oxidativo em sêmen ovino criopreservado / Effect of glutathione on ovine cryopreserved sperm function and oxidative status
It is well known that sperm is extremely susceptible to the oxidative stress. This occurs especially due to the high content of poly-unsaturated fatty acids (PUF As) in its plasma membrane. The PUF As provide the necessary fluidity to the plasma membrane, which allows the sperm to move. However the double bonds present in those fatty acids are more susceptib
Publicado em: 2009
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10. Efeitos de terpenos nas membranas de estrato córneo estudados por ressonância paramagnética eletrônica / Effects of terpenes on the stratum corneum membranes studied by electron paramagnetic resonance
The interaction of the skin penetration enhancers DL-menthol, -terpineol, 1,8-cineole and (+)-limonene with membranes of the uppermost skin layer, the stratum corneum (SC) and with multilamellar vesicles from 1,2-dipalmitoyl-sn-glycero-3-phosphaticylcholine (DPPC)is investigated by electron paramagnetic resonance (EPR) spectroscopy using spin-labeled
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/02/2008
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11. Fosfolipase A2, fluidez de membrana e proteína precursora do amilóide em plaquetas na doença de Alzheimer e comprometimento cognitivo leve / Phospholipase A2, membrane fluidity and amyloid precursor protein in platelets in Alzheimers disease and mild cognitive impairment
A Doença de Alzheimer (DA) é uma desordem neurodegenerativa progressiva que causa comprometimento cognitivo em idosos. O diagnóstico clínico da DA é complexo. Existe uma grande necessidade de técnicas capazes de detectar a doença nos estágios iniciais, tanto para auxiliar o diagnóstico quanto para monitorar a efetividade dos tratamentos disponíveis
Publicado em: 2007
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12. Effect of metallic pollutants in marine algae pigments contents and evaluation of carotenes structural features in mimetic membranes / Efeito de poluentes metálicos nos níveis de pigmentos fotossintéticos presentes em algas marinhas e avaliação do papel estrutural de carotenos em membranas miméticas
This work involves the study of the levels of photosynthetic pigments, carotenoids and chlorophylls, contained in the marine algae Tetraselmis gracilis and Gracilaria tenuistipitata, under conditions of cellular senescence and anthropogenic stress (metallic pollution). Due to the fundamental organizational role of carotenoids in thylakoid membranes, its stru
Publicado em: 2007