Membrane Interactions
Mostrando 1-12 de 1832 artigos, teses e dissertações.
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1. Concentration of soybean lecithin affects short-term storage success of goat semen related with seminal plasma removal
Abstract The objective of this study was to investigate the need of seminal plasma removal for short-term cooling of buck semen in soybean lecithin (SL) based extender. Each pool was divided equally, and one half was subjected to centrifugation to remove seminal plasma (SP-), while the other half remained with seminal plasma (SP+). Then, both SP+ and SP- sam
Anim. Reprod.. Publicado em: 25/11/2019
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2. Compatibility of GROMOS-Derived Atomic Parameters for Lipopolysaccharide Membranes with the SPC/E Water Model and Alternative Long-Range Electrostatic Treatments Using Single Nonbonded Cutoff and Atom-Based Charge Schemes
Recent developments of GROMACS v.2016 ceased to support methodological approaches used in the development and validation of the GROMOS force field. We investigated the performance of a previously developed extension of the GROMOS force field for lipopolysaccharides to reproduce the structural dynamics of bacterial outer membrane (OM) using a single cutoff fo
J. Braz. Chem. Soc.. Publicado em: 21/10/2019
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3. AVALIAÇÃO DO PERFIL DE LIBERAÇÃO DO FÁRMACO IBUPROFENO EM MEMBRANAS SIMÉTRICAS E ASSIMÉTRICAS DE ACETATO DE CELULOSE: EFEITO DA MORFOLOGIA
Cellulose derivatives still receive special attention in today biomedical applications due to their biocompatibility, ability to form resistant membranes and compatibility with various bioactive agents. In this work, cellulose acetate (CA) was used to prepare membranes with different morphologies aiming to evaluate the release profile of the drug ibuprofen (
Quím. Nova. Publicado em: 21/10/2019
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4. BaltDC: purification, characterization and infrared spectroscopy of an antiplatelet DC protein isolated from Bothrops alternatus snake venom
Abstract Background: Snake venoms are a complex mixture of proteins, organic and inorganic compounds. Some of these proteins, enzymatic or non-enzymatic ones, are able to interact with platelet receptors, causing hemostatic disorders. The possible therapeutic potential of toxins with antiplatelet properties may arouse interest in the pharmacological areas.
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 08/02/2018
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5. Ocellatin peptides from the skin secretion of the South American frog Leptodactylus labyrinthicus (Leptodactylidae): characterization, antimicrobial activities and membrane interactions
Abstract Background The availability of antimicrobial peptides from several different natural sources has opened an avenue for the discovery of new biologically active molecules. To the best of our knowledge, only two peptides isolated from the frog Leptodactylus labyrinthicus, namely pentadactylin and ocellatin-F1, have shown antimicrobial activities. The
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 20/02/2017
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6. Catostylus tagi: partial rDNA sequencing and characterisation of nematocyte structures using two improvements in jellyfish sample preparation
AbstractBackground More than 200 Scyphozoa species have been described, but few have been properly studied regarding their chemical and genetic characteristics.Catostylus tagi, an edible Scyphozoa and the sole European Catostylidae, occurs in summer at Tagus and Sado estuaries. Neither a systematic comparison between the two Catostyluscommunities nor a chemi
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 10/11/2015
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7. Allosteric interactions between receptor site 3 and 4 of voltage-gated sodium channels: a novel perspective for the underlying mechanism of scorpion sting-induced pain
AbstractBackground BmK I, a site-3-specific modulator of voltage-gated sodium channels (VGSCs), causes pain and hyperalgesia in rats, while BmK IT2, a site-4-specific modulator of VGSCs, suppresses pain-related responses. A stronger pain-related effect has been previously attributed to Buthus martensi Karsch (BmK) venom, which points out the joint pharmacolo
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 10/11/2015
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8. Colistin and anti-Gram-positive bacterial agents against Acinetobacter baumannii
Introduction Acinetobacter baumannii has attained an alarming level of resistance to antibacterial drugs. Clinicians are now considering the use of older agents or unorthodox combinations of licensed drugs against multidrug-resistant strains to bridge the current treatment gap. We investigated the in vitro activities of combination treatments that included
Rev. Soc. Bras. Med. Trop.. Publicado em: 2014-08
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9. Interaction of antimicrobial peptide Plantaricin149a and four analogs with lipid bilayers and bacterial membranes
The amidated analog of Plantaricin149, an antimicrobial peptide from Lactobacillus plantarum NRIC 149, directly interacts with negatively charged liposomes and bacterial membranes, leading to their lysis. In this study, four Pln149-analogs were synthesized with different hydrophobic groups at their N-terminus with the goal of evaluating the effect of the mod
Braz. J. Microbiol.. Publicado em: 04/02/2014
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10. Trichomonas vaginalis and Tritrichomonas foetus: interaction with fibroblasts and muscle cells - new insights into parasite-mediated host cell cytotoxicity
Trichomonas vaginalis and Tritrichomonas foetus are parasitic, flagellated protists that inhabit the urogenital tract of humans and bovines, respectively. T. vaginalis causes the most prevalent non-viral sexually transmitted disease worldwide and has been associated with an increased risk for human immunodeficiency virus-1 infection in humans. Infections by
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-09
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11. Chlorhexidine: beta-cyclodextrin inhibits yeast growth by extraction of ergosterol
Chlorhexidine (Cx) augmented with beta-cyclodextrin (β-cd) inclusion compounds, termed Cx:β-cd complexes, have been developed for use as antiseptic agents. The aim of this study was to examine the interactions of Cx:β-cd complexes, prepared at different molecular ratios, with sterol and yeast membranes. The Minimal Inhibitory Concentration (MIC) against t
Brazilian Journal of Microbiology. Publicado em: 2012-06
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12. Measuring bacterial cells size with AFM
Atomic Force Microscopy (AFM) can be used to obtain high-resolution topographical images of bacteria revealing surface details and cell integrity. During scanning however, the interactions between the AFM probe and the membrane results in distortion of the images. Such distortions or artifacts are the result of geometrical effects related to bacterial cell h
Brazilian Journal of Microbiology. Publicado em: 2012-03