Messenger
Mostrando 1-12 de 2367 artigos, teses e dissertações.
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1. Gene Silencing Therapeutics in Cardiology: A Review Article
Abstract Therapeutics that inhibit enzymes, receptors, ion channels, and cotransporters have long been the mainstay of cardiovascular medicine. Now, oligonucleotide therapeutics offer a modern variation on this paradigm of protein inhibition. Rather than target a protein, however, small interfering ribonucleic acids and antisense oligonucleotides target the
International Journal of Cardiovascular Sciences. Publicado em: 2022
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2. Two cases of subacute thyroiditis after different types of SARS-CoV-2 vaccination
SUMMARY Although the development of subacute thyroiditis (SAT) following viral infections is well-documented, the actual mechanism has not been clearly elucidated. The occurrence of SAT after vaccination has been reported in several case series and possible mechanisms such as molecular mimicry due to the exposure to viral proteins and/or abnormal reactogenic
Archives of Endocrinology and Metabolism. Publicado em: 2022
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3. Blood mRNA Expression Profiles of Autophagy, Apoptosis, and Hypoxia Markers on Blood Cardioplegia and Custodiol Cardioplegia Groups
Abstract Introduction: Blood cardioplegia (BC) and Custodiol cardioplegia (CC) have been used for a long time in open heart surgery and are highly effective solutions. The most controversial issue among these two is whether there is any difference between them regarding myocardial damage after ischemia surgery. In this study, autophagy, apoptosis, and hypox
Braz. J. Cardiovasc. Surg.. Publicado em: 2021-06
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4. PERFORMATIVIDADE DE RAÇA INTERSECCIONADA POR GÊNERO E SEXUALIDADE EM UMA RODA DE CONVERSA ENTRE MULHERES NEGRAS
RESUMO Neste artigo, pretendo mobilizar o conceito de performatividade racial intersetada por gênero e sexualidade e analisá-lo na interação de mulheres negras em um círculo de conversação on-line. Para atingir este objetivo, analiso um círculo de conversação online comigo e com outras seis mulheres negras através do Messenger e baseio minha anál
Trab. linguist. apl.. Publicado em: 2021-04
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5. Estresse, Mulheres e Infarto Agudo do Miocárdio: O que se Sabe?
Abstract Objective: To modify the chronic atrial fibrillation of atrial tachycardia pacing in beagles with a homemade pacemaker placed outside the body and to evaluate connective tissue growth factor and fibrosis of atrial tissue in our modified atrial tachycardia pacing beagle model. Methods: Twelve adult beagles of either sex were randomly divided into
Arq. Bras. Cardiol.. Publicado em: 2020-10
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6. A Modified Beagle Model of Inducible Atrial Fibrillation Using a Right Atrium Pacemaker
Abstract Objective: To modify the chronic atrial fibrillation of atrial tachycardia pacing in beagles with a homemade pacemaker placed outside the body and to evaluate connective tissue growth factor and fibrosis of atrial tissue in our modified atrial tachycardia pacing beagle model. Methods: Twelve adult beagles of either sex were randomly divided into
Braz. J. Cardiovasc. Surg.. Publicado em: 2020-10
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7. Distinct Niemann-Pick Disease Type C Clinical, Cytological, and Biochemical Phenotype in an Adult Patient With 1 Mutated, Overexpressed NPC1 Allele
Abstract Niemann-Pick disease type C (NP-C) is a rare autosomal-recessive neurovisceral lysosomal storage disease. We report on a juvenile onset, now 25-year-old female patient with typical neurologic symptoms, including vertical gaze palsy, of NP-C. The diagnosis was supported by a positive filipin test (“variant biochemical phenotype” of cholesterol ac
J. inborn errors metab. screen.. Publicado em: 19/06/2019
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8. Expression analysis of long non-coding RNAs in a renal ischemia-reperfusion injury model
Abstract Purpose: To investigate the long non-coding RNAs (lncRNAs) profile on renal ischemia reperfusion in a mouse model. Methods: Microarray analysis was used to study the expression of misregulated lncRNA in a mouse model of renal ischemia reperfusion(I/R) with long ischemia time. Quantitative real-time PCR (qPCR) was used to verify the expression of
Acta Cir. Bras.. Publicado em: 29/04/2019
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9. MicroRNAs: new biomarkers and promising therapeutic targets for diabetic kidney disease
Resumo A doença renal do diabetes (DRD) é uma complicação crônica do diabetes mellitus associada à elevada morbidade e mortalidade, considerada um problema de saúde mundial. Dentre os fatores associados ao desenvolvimento e à progressão da DRD, destacam-se os microRNAs, que consistem em pequenas moléculas de RNA que regulam a expressão gênica por
J. Bras. Nefrol.. Publicado em: 07/02/2019
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10. FGFR1 is an independent prognostic factor and can be regulated by miR-497 in gastric cancer progression
Fibroblast growth factor receptor 1 (FGFR1) has been reported in gastric cancer to be a prognostic factor. However, miR-497-targeted FGFR1 has not been explored in the carcinogenesis of gastric cancer. The present study intended to revalidate the prognostic significance of FGFR1 in patients with gastric cancer, and the mechanism of miR-497-regulated FGFR1 wa
Braz J Med Biol Res. Publicado em: 23/11/2018
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11. Inflammatory cytokines in leprosy reactions and periodontal diseases
ABSTRACT The inflammatory cytokines involved in the immune response to chronic periodontal disease (CPD) in the context of leprosy reactions (LR) were analyzed in 57 new cases of multibacillary leprosy (MBL). They were stratified by the presence of CPD and LR. Messenger RNA (mRNA) expression of inflammatory mediators was determined by qRT-PCR using skin biop
Rev. Inst. Med. trop. S. Paulo. Publicado em: 08/11/2018
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12. Non-invasive messenger RNA transcriptional evaluation in human kidney allograft dysfunction
The aim of the present study was to evaluate messenger RNA expression in kidney allograft recipients. Forty-four kidney transplant recipients were evaluated up to three months after grafting. After transplantation, peripheral blood samples were drawn sequentially for real-time polymerase chain reaction analyses of perforin and TIM-3 genes. Biopsies were obta
Braz J Med Biol Res. Publicado em: 17/05/2018