Miotoxicity
Mostrando 1-4 de 4 artigos, teses e dissertações.
-
1. Estudo da toxicidade muscular pelo uso de estatinas em pacientes hipercolesterolêmicos: avaliação pela espectroscopia do hidrogênio por ressonância magnética / Study of muscle toxicity by use of statins in hypercholesterolemic patients: evaluation by proton magnetic resonance spectroscopy
Cardiovascular disease is the leading cause of death in the western world and statins are the most prescribed medications for prevention and treatment. Despite being the most prescribed drugs, they are still under-used. The main cause of interruption of statin treatment is myopathy. Among the mechanisms involved in the pathophysiology of myotoxicity, deficie
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/11/2012
-
2. Modificações quimicas de fosfolipases A2 procedentes do veneno de Crotalus durissus ruruima e Crotalus durissus cumanensis : estudos dos efeitos cataliticos e farmacologicos / Chemical modifications of phospholipases A2 coming from the poison of Crotalus durissus ruruima and Crotalus durissus cumanesis : studies of the catalytic and pharmacological effects
The serpents of the genus Crotalus include several species widely distributed in the American continent. The poisons crotálicos of the serpents found in Brazil, they present own characteristics. Among the components bioativos, the phospholipases A2 (E.C. 3.1.1.4.) standing out to be the main component, such enzymes are dependents of calcium and hidrolise th
Publicado em: 2007
-
3. Purificação e caracterização de uma nova fosfolipase A2 ácida da peçonha de Bothrops pauloensis
Phospholipases A2 (PLA2) is small enzymes that present molecular mass around 15kDa and are found in a variety of biological and cellular fluids as fluid sinovial, macrophages, platelet, pancreatic tissue, among others. The present work describes the purification and chemical, biological and enzymatic characterization of an acidic phospholipase A2 of Bothrops
Publicado em: 2006
-
4. PurificaÃÃo e caracterizaÃÃo de uma nova fosfolipase A2 Ãcida da peÃonha de Bothrops pauloensis
Phospholipases A2 (PLA2) is small enzymes that present molecular mass around 15kDa and are found in a variety of biological and cellular fluids as fluid sinovial, macrophages, platelet, pancreatic tissue, among others. The present work describes the purification and chemical, biological and enzymatic characterization of an acidic phospholipase A2 of Bothrops
Publicado em: 2006