Mouse Embryo
Mostrando 1-12 de 978 artigos, teses e dissertações.
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1. CCR3 antagonist impairs estradiol-induced eosinophil migration to the uterus in ovariectomized mice
Eosinophils are abundant in the reproductive tract, contributing to the remodeling and successful implantation of the embryo. However, the mechanisms by which eosinophils migrate into the uterus and their relationship to edema are still not entirely clear, since there are a variety of chemotactic factors that can cause migration of these cells. Therefore, to
Braz J Med Biol Res. Publicado em: 2020-01
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2. The perturbed expression of m6A in parthenogenetic mouse embryos
Abstract Parthenogenetically activated oocytes cannot develop to term in mammals owing to abnormal epigenetic modifications. Methylation of the N6 position of adenosine (m6A) is a post-transcriptional epigenetic modification of RNA. To investigate the role of m6A methylation in parthenogenetic (PA) embryonic development, we analyzed METTL3, METTL14, FTO, ALK
Genet. Mol. Biol.. Publicado em: 14/11/2019
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3. Cytotoxicity and genotoxicity of coronaridine from Tabernaemontana catharinensis A.DC in a human laryngeal epithelial carcinoma cell line (Hep-2)
Cancer has become a major public health problem worldwide and the number of deaths due to this disease is increasing almost exponentially. In the constant search for new treatments, natural products of plant origin have provided a variety of new compounds to be explored as antitumor agents. Tabernaemontana catharinensis is a medicinal plant that produces alk
Genet. Mol. Biol.. Publicado em: 01/02/2013
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4. Behavior of the P1.HTR mastocytoma cell line implanted in the chorioallantoic membrane of chick embryos
The P1.HTR cell line includes highly transfectable cells derived from P815 mastocytoma cells originating from mouse breast tissue. Despite its widespread use in immunogenic studies, no data are available about the behavior of P1.HTR cells in the chick embryo chorioallantoic membrane model. The objective of the present investigation was to study the effects o
Braz J Med Biol Res. Publicado em: 11/01/2013
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5. Trichomonas vaginalis and Tritrichomonas foetus: interaction with fibroblasts and muscle cells - new insights into parasite-mediated host cell cytotoxicity
Trichomonas vaginalis and Tritrichomonas foetus are parasitic, flagellated protists that inhabit the urogenital tract of humans and bovines, respectively. T. vaginalis causes the most prevalent non-viral sexually transmitted disease worldwide and has been associated with an increased risk for human immunodeficiency virus-1 infection in humans. Infections by
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-09
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6. Modulation of murine blastocyst hatching in vitro by glutamine and tryptophan
Enrichment of culture media with amino acids improves embryo development. However, little is known about the specific action of each amino acid during embryogenesis. The present study was undertaken to examine the effect of L-glutamine (Gln) and tryptophan (Trp) on mouse embryo hatching, expansion and viability in vitro. Blastocysts were collected from 6- to
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-08
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7. Pronounced segregation of donor mitochondria introduced by bovine Ooplasmic tranfer to the female germ-line.
Ooplasmic transfer (01) has been used in basic mouse research for studying lhe segregation of mtDNA, as well as in human assisted reproduction for improving embryo development in cases of persistent developmental failure. Using cattle as a large-animal model, we demonstrate that lhe moderate amount of mitochondria introduced by OT is transmitted to lhe offsp
Biology of Reproduction. Publicado em: 2011
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8. In vitro and in vivo survival of mouse morulas and blastocysts following vitrification in 45% glycerol / Sobrevivência in vitro e in vivo de mórulas e blastocistos murinos vitrificados em meio contendo 45% de glicerol
A toxidez do agente crioprotetor é um dos aspectos mais críticos no sucesso da vitrificação de embriões mamíferos, variando conforme a concentração, o tempo e a temperatura de exposição. Além disto, embriões de diferentes espécies ou estádios de desenvolvimento podem tolerar diferentes níveis de exposição a agentes crioprotetores. Este estud
Publicado em: 2011
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9. Nova técnica para contagem do número de células de blastocistos
A simplified, fast, and innovative method was developed to count the total cell number in blastocysts. Murine blastocysts (N = 195) were used in this study. They were obtained after 10h culture of initial blastocysts, compact morulae grades I and II recovered from superovulated mouse. After culture, the blastococysts were selected to test the new proposal of
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Publicado em: 2010-12
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10. Estudo do padrão de inativação do cromossomo X em tecido extra-embrionário humano / X-chromosome inactivation pattern in human extra-embryonic tissue
Imprinted inactivation of the paternal X chromosome in marsupials is the primordial mechanism of dosage compensation for X-linked genes between females and males in Therians. In Eutherian mammals, X chromosome inactivation (XCI) evolved into a random process in cells from the embryo proper, where either the maternal or paternal X can be inactivated. However,
Publicado em: 2010
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11. Efeitos biológicos e avaliação dose-resposta das partículas de exaustão do diesel sobre o desenvolvimento embrionário inicial de camundongos / Biological effects and dose-response assessment of diesel exhaust particles on in vitro early embryo development in mice
Experimentos anteriores realizados em nosso laboratório indicam que o sucesso gestacional é afetado pela poluição atmosférica. O presente estudo teve como objetivo avaliar os efeitos biológicos associados a uma curva dose resposta das partículas de exaustão do diesel (PED) sobre o desenvolvimento embrionário inicial e o potencial de implantação, u
Publicado em: 2010
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12. Identificação e caracterização funcional dos elementos cis-regulatorios da miostatina / Identification and functional characterization of the cis-regulatory elements of myostatin
The Myostatin protein (also known as GDF8) is a member of the transforming growth factor-β (TGF-β) superfamily and is expressed almost exclusively in skeletal muscle, both in the embryo and in the adult, where the protein circulates in the blood flow. It was initially identified in 1997 by MCPHERRON et al., and since then many studies have been dem
Publicado em: 2009