Muscle Fiber Regeneration
Mostrando 1-12 de 18 artigos, teses e dissertações.
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1. Local inhibition of nitrergic activity in tenotomized rats accelerates muscle regeneration by increasing fiber area and decreasing central core lesions
Muscular atrophy is a progressive degeneration characterized by muscular proteolysis, loss of mass and decrease in fiber area. Tendon rupture induces muscular atrophy due to an intrinsic functional connection. Local inhibition of nitric oxide synthase (NOS) by Nω-nitro-L-arginine methyl ester (L-NAME) accelerates tendon histological recovery and induces fun
Braz J Med Biol Res. Publicado em: 20/02/2017
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2. Morphological aspects and Cox-2 expression after exposure to 780-nm laser therapy in injured skeletal muscle: an in vivo study
Background: The effectiveness of low-level laser therapy in muscle regeneration is still not well known. Objective: To investigate the effects of laser irradiation during muscle healing. Method: For this purpose, 63 rats were distributed to 3 groups: non-irradiated control group (CG); group irradiated at 10 J/cm² (G10); and group irradiated at 50 J/cm² (G
Braz. J. Phys. Ther.. Publicado em: 29/08/2014
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3. Alterations of morphology, mechanical and osteogenic capacity of mdx mice bones / Alterações da morfologia, resistência mecânica e capacidade osteogênica dos ossos de camundongos mdx
Duchenne muscular dystrophy (DMD) is a neuromuscular disease caused by lack of dystrophin. DMD patients have brittle bones because of muscle weakness and use of glucocorticoids. The mdx mouse is widely used as experimental model for the study of DMD and it presents lack of dystrophin, intense inflammatory process and muscle fiber degeneration. Moreover, it p
Publicado em: 2011
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4. Influence of the number of stitches in axonal regeneration and production of extracellular matrix in end-to-end epineural suture in the rat sciatic nerve / Influência do número de pontos na regeneração axonal e produção de matriz extracelular na sutura epineural terminoterminal no nervo ciático do rato
PURPOSE: After an injury to a peripheral nerve, its repair is performed with epineural sutures of the stumps using nylon. The inflammatory process caused by the passage of the needle and the presence of suture material with the consequent formation of scar tissue at the suture line becomes an obstacle to axonal regeneration after nerve repair. In the literat
Publicado em: 2010
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5. Effects of L-aginine and deflazacort in muscle regeneration after experimental envenoming by Bothrops jararacussu / Efeito da L-arginina e deflazacort na regeneração muscular apos o envenenamento experimental por Bothrops jararacussu
The study evaluates the effect of deflazacort (DFZ), an anti-inflammatory oxalazine derivative of prednisone, on muscle regeneration following myonecrosis experimentally induced by B. jararacussu venom. Mice (n=15) right tibialis anterioris muscle was injected with 80 µg of venom. Two groups of animals (n=10) was treated during 5 and 20 days with a daily in
Publicado em: 2009
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6. Ação de antiinflamatorios não-esteroides na degeneração/regenação de fibras musculares distroficas de camundongos mdx / Nonsteroidal antiinflamatory influence in the degeneration/regeneration cycles of mdx mice dystrophic muscle fibers
Em fibras musculares distróficas de camundongos mdx e na distrofia muscular de Duchenne (DMD), a deficiência da distrofina provoca lesão do sarcolema e degeneração muscular. Esta deficiência está associada a alterações na estabilidade do sarcolema e aumento dos níveis intracelulares de cálcio, que podem provocar mionecrose. O mecanismo exato que p
Publicado em: 2008
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7. Protection from myonecrosis, and expression of SERCA1 and calsequestrin in dystrophic laryngeal muscles / Musculos laringeos distroficos : proteção a mionecrose, expressao de SERCA1 e calsequestrina
Duchenne muscular dystrophy (DMD) and mdx mice, a model for DMD, is characterized by the lack of dystrophin expression and muscle fiber necrosis. Some muscle are enigmatically protected and admitted that an elevated expression of calcium-binding proteins. The intrinsic laryngeal muscles (ILMs) share many anatomical and physiological properties with extra-ocu
Publicado em: 2007
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8. Sem título traduzido / Avaliação dos efeitos do ultra-som pulsado de baixa intensidade e da atividade física na musculatura esquelética de ratos submetidos ao alcoolismo crônico e posterior lesão por impacto padronizada
The skeletal muscle tissue is among the organism tissues one of the most affected by the abuse alcohol. The aim of this study was quantify the effects of chronic alcoholism on skeletal muscle of rats submitted or not to exercise training model, as well evaluate the muscle regeneration after mechanism of acute muscular injury, in the gastrocnemius muscle, thr
Publicado em: 2006
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9. Cyclosporin A preferentially attenuates skeletal slow-twitch muscle regeneration
Calcineurin, a Ca2+/calmodulin-dependent phosphatase, is associated with muscle regeneration via NFATc1/GATA2-dependent pathways. However, it is not clear whether calcineurin preferentially affects the regeneration of slow- or fast-twitch muscles. We investigated the effect of a calcineurin inhibitor, cyclosporin A (CsA), on the morphology and fiber diameter
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-04
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10. Distribuição dos receptores de acetilcolina e terminais nervosos na junção neuromuscular de fibras musculares regeneradas
Mdx mice have deficiency of dystrophin and cycles of muscle fiber regeneration. Changes in the distribution of acetylcholine receptors have been reported at the neuromuscular junction of mdx and may be a consequence of muscle fiber regeneration. At the present, we verified whether the distribution of receptors is still altered in long-term regenerated muscle
Publicado em: 2004
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11. Reparo nervoso primario em ratos, usando auto-enxerto de musculo esqueletico imediatamente apos injeção de lidocaina
We evaluated the potential of muscle autografts to perform primary nerve repair when used immediately after their preparation with lidocaine injection. The right sciatic nerve of adult Wistar rats was sectioned and muscle grafts were used 15 minutes or 24 hours after lidocaine injection, to repair a gap 1.0 cm longo Morphometric analyses showed a decrease in
Publicado em: 2002
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12. Lymphocyte antigen Leu-19 as a molecular marker of regeneration in human skeletal muscle.
Antigen Leu-19 (Leu19-Ag), a 200- to 220-kDa surface glycoprotein, was originally identified on a subset of human peripheral lymphocytes exhibiting non-major histocompatibility complex-restricted cytotoxicity. Here we report that monoclonal antibody Leu-19 (mAb-Leu19) labels structures in human skeletal muscle: (i) satellite cells, which form the stem cell p