Myod Protein
Mostrando 1-12 de 162 artigos, teses e dissertações.
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1. Small activating RNA induces myogenic differentiation of rat adipose-derived stem cells by upregulating MyoD
ABSTRACTPurpose:RNA activation (RNAa) is a mechanism of gene activation triggered by promoter-targeted small double stranded RNAs (dsRNAs), also known as small activating RNAs (saRNAs). Myogenic regulatory factor MyoD is regarded as the master activator of myogenic differentiation cascade by binding to enhancer of muscle specific genes. Stress urinary incont
Int. braz j urol.. Publicado em: 2015-08
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2. Effect of tibiotarsal joint inflammation on gene expression and cross-sectional area in rat soleus muscle
BACKGROUND: Joint inflammation is a common clinical problem in patients treated by physical therapists. The hypothesis of this study is that joint inflammation induces molecular and structural changes in the soleus muscle, which is composed mainly of slow-twitch muscle fibers. OBJECTIVE: To study the effect of tibiotarsal joint inflammation on muscle f
Braz. J. Phys. Ther.. Publicado em: 07/06/2013
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3. A participação da proteína cinase mTOR (mammalian target of rapamycin) e do fator transcricional NF-kB na regulação da expressão do GLUT4 em músculo sóleo de ratos. / The participation of protein kinase mTOR (mammalian target of rapamycin) and the transcriptional factor NF-kB in regulating the expression of GLUT4 in soleus muscle of rats.
A insulina regula a expressão de GLUT4, porém os mecanismos envolvidos nesta regulação não estão definidos. Alguns fatores de transcrição e proteínas cinases estão relacionados com a expressão de GLUT4. Assim, o objetivo desta pesquisa foi investigar a participação dos fatores de transcrição MEF2, HIF-1a e NF-
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/02/2012
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4. Expressão gênica e protéica de fatores reguladores miogênicos e da miostatina no músculo esquelético do pirarucu (Arapaima gigas) durante o crescimento / Gene and protein expression of myogenic regulatory factors and myostatin in skeletal muscle of pirarucu (Arapaima gigas) during growth
O pirarucu (Arapaima gigas) caracteriza-se como uma espécie promissora para a Aqüicultura, devido principalmente às suas características de rápido crescimento e rusticidade. Sua criação em regime intensivo tem obtido enorme sucesso, podendo alcançar até 10 quilos de peso corporal em apenas um ano de criação. O pirarucu é considerado hoje uma das
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/04/2011
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5. Efeitos do treinamento resistido associado com decanoato de nandrolona sobre a expressão gênica de moduladores de vias de hipertrofia e atrofia do músculo esquelético
Androgenic-anabolic steroids (AAS) are spread among athletes and no athletes in order to improve performance or physical appearance. AAS targets the satellite cells in skeletal muscles, which are the major precursors of the skeletal muscle, and are essential for muscle growth and repair. When activated, in the presence of several factors, including myogenic
Publicado em: 2009
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6. ALT-C, a disintegrin-like Cys-rich protein from Bothrops alternatus, increases skeletal myoblast viability
ALT-C, an ECD motif (glutamic acid, cysteine, aspartic acid) disintegrin from Bothrops alternatus snake venom, induces α2β1 integrin-mediated signaling and neutrophil chemotaxis. In vitro, in human umbilical vein endothelial cells (HUVEC), ALT-C induces cell proliferation, thus showing an interesting potential for tissue regeneration studies. This work aim
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2009
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7. Identificação e caracterização funcional dos elementos cis-regulatorios da miostatina / Identification and functional characterization of the cis-regulatory elements of myostatin
The Myostatin protein (also known as GDF8) is a member of the transforming growth factor-β (TGF-β) superfamily and is expressed almost exclusively in skeletal muscle, both in the embryo and in the adult, where the protein circulates in the blood flow. It was initially identified in 1997 by MCPHERRON et al., and since then many studies have been dem
Publicado em: 2009
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8. L-arginine administration : the effect on myocardial fibrosis and increase of the carcinogenesis in mice mdx / Administração de L-arginina : efeitos sobre a fibrose miocardica e aumento da carcinogenese em camundongos mdx
The Duchenne Muscle Dystrophy (DMD) is a myopathy characterized by dystrophin absence, which is a structural protein of the plasma membrane. The dystrophin absence leads to functional alterations followed by necrosis in the skeletal and cardiac muscle fiber. As the patients grow older, about 40% of them develop cardiomyopathy due to progressive myocardial fi
Publicado em: 2009
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9. Avaliação do padrão de degeneração e regeneração muscular em diferentes modelos murinos para distrofias musculares progressivas / Study of degeneration and regeneration pathways, in mice models for muscular dystrophies
The muscular dystrophies are a heterogeneous group of genetic diseases characterized by progressive and irreversible degeneration of skeletal muscles. Muscle weakness is the consequence of an imbalance between successive cycles of degeneration and regeneration, with further replacement of the degraded muscle fibers by adipose and connective tissues. Several
Publicado em: 2009
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10. Modulation of thyroid hormone receptor transactivation by the early region 1A (E1A)-like inhibitor of differentiation 1 (EID1)
Transcriptional activation (TA) mediated by the effect of thyroid hormones on target genes requires co-activator proteins such as the early region 1A (E1A) associated 300 kDa binding protein (p300) and the cAMP response element binding protein (CREB) binding protein (CBP), known as the p300/CBP complex, which acetylate histones 3 and 4 to allow transcription
Genetics and Molecular Biology. Publicado em: 2008
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11. Expression of myogenic regulatory factor MyoD in skeletal muscle of pacu (Piaractus mesopotamicus) during growth / Expressão do fator de regulação miogenica MyoD, na musculatura estriada esqueletica do pacu (Piaractus mesopotamicus), durante o crescimento
Skeletal muscle growth in fish occurs by hypertrophy and hyperplasia and is dependent of the proliferation and differentiation of myogenic progenitor cells, events regulated by the diferential expression of the myogenic regulatory factors (MRFs). The aim of this study was to analyze the hyperplasia and hypertrophy processes and the MRF MyoD expression in the
Publicado em: 2007
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12. Expressão de fatores de regulação miogenica e metaloproteinases no musculo estriado esqueletico de ratos com insuficiencia cardiaca / Myogenic regulatory factors and metalloproteinase expression in rat skeletal muscle with heart failure
Background: Heart failure (HF) is associated with a skeletal muscle myopathy with increased expression of fast myosin heavy chains (MHC) and extracellular matrix (ECM) alterations. The skeletal muscle-specific molecular regulatory mechanisms controlling MHC expression during HF have not been described. Myogenic regulatory factors (MRF), a family of transcrip
Publicado em: 2006