Myosin Heavy Chain
Mostrando 1-12 de 461 artigos, teses e dissertações.
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1. Cardiac protein expression patterns are associated with distinct inborn exercise capacity in non-selectively bred rats
In the present study, we successfully demonstrated for the first time the existence of cardiac proteomic differences between non-selectively bred rats with distinct intrinsic exercise capacities. A proteomic approach based on two-dimensional gel electrophoresis coupled to mass spectrometry was used to study the left ventricle (LV) tissue proteome of rats wit
Braz J Med Biol Res. Publicado em: 11/01/2018
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2. Effect of hepatocyte growth factor and angiotensin II on rat cardiomyocyte hypertrophy
Angiotensin II (Ang II) plays an important role in cardiomyocyte hypertrophy. The combined effect of hepatocyte growth factor (HGF) and Ang II on cardiomyocytes is unknown. The present study was designed to determine the effect of HGF on cardiomyocyte hypertrophy and to explore the combined effect of HGF and Ang II on cardiomyocyte hypertrophy. Primary cardi
Braz J Med Biol Res. Publicado em: 2012-12
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3. Eccentric and concentric cardiac hypertrophy induced by exercise training: microRNAs and molecular determinants
Among the molecular, biochemical and cellular processes that orchestrate the development of the different phenotypes of cardiac hypertrophy in response to physiological stimuli or pathological insults, the specific contribution of exercise training has recently become appreciated. Physiological cardiac hypertrophy involves complex cardiac remodeling that occ
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-09
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4. Immediate response of myocardium to pressure overload includes transient regulation of genes associated with mitochondrial bioenergetics and calcium availability
Ventricular hypertrophy is one of the major myocardial responses to pressure overload (PO). Most studies on early myocardial response focus on the days or even weeks after induction of hypertrophic stimuli. Since mechanotransduction pathways are immediately activated in hearts undergoing increased work load, it is reasonable to infer that the myocardial gene
Genetics and Molecular Biology. Publicado em: 22/01/2010
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5. Molecular regulation of atrial-specific expression of the SMyHC3 gene. / Regulação molecular da expressão atrial - específica do gene SMyHC3.
Para elucidar as vias genéticas controlando a formação das câmaras cardíacas, foi analisada a regulação do promotor atrial-específico do gene de codorna que codifica a isoforma lenta da cadeia pesada de miosina (slow myosin heavy chain 3 -SMyHC3). Em camundongos transgênicos, a expressão atrial-específica dos 840 pb do promotor SMyHC3 fundido ao g
Publicado em: 2010
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6. Isolamento e caracterizaÃÃo parcial dos Genes beta-actina e miosina de cadeia pesada do CamarÃo rosa Farfantepenaeus subtilis / Isolation and partial characterization of genes beta-actin and myosin heavy chain shrimp Farfantepenaeus subtilis
The penaeid shrimp Farfantepenaeus subtilis is an important native species for fisheries industry in Brazil. Among marine shrimps of commercial importance, penaeids are recognized as a valuable resource for fishery and aquaculture in tropical and subtropical regions. However, data on these species is extremely reduced, especially concerning genetic elements
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 04/03/2009
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7. Characterization of the variety on cross sectional area, capillary density and neonatal myosin expression in the masseter and temporalis muscle / Caracterização da variação do calibre das fibras musculares, densidade capilar e expressão de miosina neonatal nos músculos masseter e temporal
Temporomandibular disfunction (TMD) is a colletive term that refers to different clinical problems of the temporomandibular joint and the jaw muscles. These disfunctions are characterizied meanly by pain, joint sounds and irregular or limited mandibular function. The jaw muscles can be involved in the TMD of muscle etiology, and by definition they are the on
Publicado em: 2009
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8. ALT-C, a disintegrin-like Cys-rich protein from Bothrops alternatus, increases skeletal myoblast viability
ALT-C, an ECD motif (glutamic acid, cysteine, aspartic acid) disintegrin from Bothrops alternatus snake venom, induces α2β1 integrin-mediated signaling and neutrophil chemotaxis. In vitro, in human umbilical vein endothelial cells (HUVEC), ALT-C induces cell proliferation, thus showing an interesting potential for tissue regeneration studies. This work aim
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2009
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9. Expressão dos fatores de regulação miogenica e de cadeia pesada da miosina no musculo estriado esquelitico da tilapia do Nilo (Oreochromis niloticus) durante o crecimento / Miogenic regulatory factors and myosin heavy chain expression in the striated skeletal muscle of the Nile tilapia (Oreochromis niloticus) during growth
Nos peixes, o conhecimento dos fatores que controlam o crescimento muscular e a análise das proteínas miofibrilares, é importante para entender a dinâmica do crescimento, a plasticidade e as adaptações musculares, principalmente, em espécies com grande valor comercial como a tilápia do Nilo (Oreochromis niloticus). No presente estudo, utilizou-se a t
Publicado em: 2008
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10. AnÃlises histolÃgicas e proteÃmicas do miÃcito cardÃaco de ratos submetidos a diferentes intensidades de exercÃcio
Scientific literature have been described the regular which as an important factor in the health improvement. Among several causes have been related to this phenomenon, it was observed a crucial point that included the improvement of heart potency. This enhancement could be related to several factors such as cardiac muscle cells hypertrophy, which was consid
Publicado em: 2007
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11. Early remodeling of rat cardiac muscle induced by swimming training
The aim of the present investigation was to study the effect of acute swimming training with an anaerobic component on matrix metallopeptidase (MMP) activity and myosin heavy chain gene expression in the rat myocardium. Animals (male Wistar rats, weighing approximately 180 g) were trained for 6 h/day in 3 sessions of 2 h each for 1 to 5 consecutive days (N =
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-05
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12. Avaliação das interações proteicas da quinase de adesão focal (FAK) em miocitos cardiacos : caracterização estrutural e funcional da interação da FAK com a cadeia pesada de miosina sarcomerica
Mechanical stress is a major factor involved in the development of myocardial adaptive and maladaptive changes in heart diseases. Local mechanical forces activate signaling mechanisms in cardiac myocytes inducing the expression of specific genetic programs linked to myocardial structural and functional remodeling. Although mechanical forces might directly tr
Publicado em: 2005