Nas Net Analyte Signal
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Simultaneous Quantification of Amorphous and Crystalline Valsartan in Tablets Using Raman Spectroscopy and Chemometrics Tools
Valsartan is an antihypertensive active pharmaceutical ingredient (API), it is used in the amorphous state in the commercial products. As amorphous materials are metastable, amorphous valsartan can crystallize to valsartan E, promoting changes in the dissolution and bioavailability of the drug. Tablets containing metastable forms of APIs need special conditi
Journal of the Brazilian Chemical Society. Publicado em: 2022
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2. IDENTIFICAÇÃO DE ADULTERANTES DE BIODIESEL METÍLICO DE CRAMBE EM MISTURAS COM DIESEL, USANDO FT-MIR E CARTAS DE CONTROLE MULTIVARIADAS BASEADAS NO SINAL ANALÍTICO LÍQUIDO
Adulterants in biodiesel/diesel blends modifies its physical and chemical properties. In this work, Fourier Transform Mid-Infrared spectrometry (FT-MIR) and multivariate control charts based on Net Analyte Signal (NAS) were used to monitor the quality of Crambe methyl biodiesel in relation to the biodiesel content and the presence of adulterants. The calibra
Quím. Nova. Publicado em: 2020-01
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3. Aplicação de quimioterapia e espectroscopia no infravermelho no controle de qualidade de biodiesel e mistura biodiesel/diesel / Application of chemometrics and infrared spectroscopy in the quality control of biodiesel and biodiesel blend
Multivariate control charts in jointly with near infrared spectroscopy were developed to verify the quality of biodiesel blends (2% of biodiesel and 98% of diesel). The control charts were built using the net analyte signal, generating three charts: the NAS chart that corresponds to the analyte of interest (biodiesel in this case), the interference chart tha
Publicado em: 2008
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4. Utilização do sinal analitico liquido para avaliação de modelos de calibração multivariada atraves do calculo de figuras de merito e de cartas de controle / Utilization of net analyte signal for validation of models of multivariate calibration by using figure of merit and chart control
This study was mainly intended to elaborate the validation of multivariate calibration models based on the determination of figures of merit and multivariate control charts constructed with data from Nimesulide tablets upon near-infrared spectroscopy use. A total of 69 synthetic samples were prepared containing the active principle (Nimesulide) in the range
Publicado em: 2007
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5. Determination of figures of merit for near-infrared and raman spectrometry by net analyte signal analysis for a 4-component solid dosage system
Process analytical technology has elevated the role of sensors in pharmaceutical manufacturing. Often the ideal technology must be selected from many suitable candidates based on limited data. Net analyte signal (NAS) theory provides an effective platform for method characterization based on multivariate figures of merit (FOM). The objective of this work was
Springer-Verlag.
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6. Acoustic-resonance spectrometry as a process analytical technology for the quantification of active pharmaceutical ingredient in semi-solids
The purpose of this study was to demonstrate acoustic resonance spectrometry (ARS) as an alternative process analytical technology to near infrared (NIR) spectroscopy for the quantification of active pharmaceutical ingradient (API) in semi-solids such as creams, gels, ointments, and lotions. The ARS used for this research was an inexpensive instrument constr
Springer-Verlag.