Neonates Rats
Mostrando 1-12 de 48 artigos, teses e dissertações.
-
1. Effect of metronidazole on placental and fetal development in albino rats
Abstract Metronidazole is an antiprotozoal and antibacterial used in gynecology and obstetrics for the treatment of parasitic infections. However, despite having clinical use for more than three decades, questions about the safety of its use during pregnancy is not well understood. Thus, the present study evaluated the effect of metronidazole on placental an
Anim. Reprod.. Publicado em: 25/11/2019
-
2. Biomarker responses (serum biochemistry) in pregnant female wistar rats and histopathology of their neonates exposed prenatally to pesticides
Experiments were conducted to investigate the effects on health of pregnant female rats exposed to pesticides glyphosate and carbendazim. Glyphosate is used as herbicide and carbendazim as a fungicide; all are commercially available readily for various agricultural and domestic purposes. The hypothesis tested in this investigation is that pesticide exposure
Braz. J. Pharm. Sci.. Publicado em: 10/07/2019
-
3. Ventilation-induced changes correlate to pulmonary vascular response and VEGF, VEGFR-1/2, and eNOS expression in the rat model of postnatal hypoxia
Neonatal asphyxia occurs due to reduction in oxygen supply to vital organs in the newborn. Rapid restoration of oxygen to the lungs after a long period of asphyxia can cause lung injury and decline of respiratory function, which result from the activity of molecules that induce vascular changes in the lung such as nitric oxide (NO) and vascular endothelial g
Braz J Med Biol Res. Publicado em: 08/10/2018
-
4. Brain caspase-3 and intestinal FABP responses in preterm and term rats submitted to birth asphyxia
Neonatal asphyxia can cause irreversible injury of multiple organs resulting in hypoxic-ischemic encephalopathy and necrotizing enterocolitis (NEC). This injury is dependent on time, severity, and gestational age, once the preterm babies need ventilator support. Our aim was to assess the different brain and intestinal effects of ischemia and reperfusion in n
Braz J Med Biol Res. Publicado em: 23/06/2016
-
5. Effects of excess maternal thyroxin on the bones of rat offspring from birth to the post-weaning period
ABSTRACT Objective To evaluate, in rat offspring, bone changes induced by excess maternal thyroxin during pregnancy and lactation, and to assess the reversibility of these changes after weaning. Material and methods Twenty Wistar rats were distributed in two groups, hyperthyroid and control, that were treated daily with L-thyroxin (50 mcg/animal) and pla
Arch. Endocrinol. Metab.. Publicado em: 2016-04
-
6. Transplantation of mononuclear cells from human umbilical cord blood promotes functional recovery after traumatic spinal cord injury in Wistar rats
Cell transplantation is a promising experimental treatment for spinal cord injury. The aim of the present study was to evaluate the efficacy of mononuclear cells from human umbilical cord blood in promoting functional recovery when transplanted after a contusion spinal cord injury. Female Wistar rats (12 weeks old) were submitted to spinal injury with a MASC
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-01
-
7. Influência da obesidade e da resistência à insulina sobre o desenvolvimento tumoral: efeito da metformina / : Obesity and insulin resistance influences in the tumor development metformin effects
The influence of obesity and insulin resistance (induced in rats by monosodium glutamate in neonates) on tumor development (5x105 Walker-256 tumor cells) and the effect of metformin (300mg/kg, by gavage, for 15 d) on it. On the 16th week, tumor cells were subcutaneously injected and the treatment started. On the 18th week, the obesity was characterized and t
Publicado em: 2010
-
8. Avaliação da toxicidade reprodutiva de ratas Wistar submetidas à ingestão do extrato etanólico das folhas de nim(Azadirachta indica A. Juss)
Neem (Azadirachta indica A. Juss) is a plant of the Meliaceae family. It is commonly used in India as a contraceptive and worldwide as a means of controlling insect proliferation.In veterinary medicine it has been gaining attention due to its anti-helmintic and ectoparasitic properties. This study aims at evaluating the effects of oral administration of the
Publicado em: 2010
-
9. Restrição alimentar intra-uterina e suas repercussões sobre o desenvolvimento da termorregulação da prole.
Background: Previous study from our laboratory has shown that intrauterine food restriction (IUFR) delayed thermoregulation of the newborns. In neonates brown adipose tissue (BAT) is essential for thermogenesis mainly due to the presence of uncoupling proteins (UCPs) and their expression can be modified by action of hormones such as thyroid hormone, leptin a
Publicado em: 2009
-
10. Crises paroxísticas recorrentes em ratos por inibição do transporte de glutamato durante o desenvolvimento / Genesis of recurrent epileptic paroxysmal burst in newborn rats after inhibition of glutamate transporters
It has been previously shown that cell-surface glutamate transporters efficiently control network activity in the maturing rodent brain, preventing the generation of seizures. In particular, inhibition of glutamate transporters by DL-TBOA leads to a pathological EEG pattern in freely moving rat pups. This is composed of partial seizures and recurrent short p
Publicado em: 2009
-
11. Analysis of the expression profile and distribution of EFHC1 gene transcript during rodent brain development and in the adult animal / Analise da expressão e localização do transcrito do gene EFHC1 no cerebro de roedores durante o desenvolvimento e no animal adulto
Epilepsy is a frequent condition that affects around 1.5% of general population and is considered worldwide as a public health problem. The term epilepsy refers to a group of chronic neurological disorders with different etiologies and prognostics. However, a common characteristic of all epilepsies is the recurrence of seizures. Juvenile myoclonic epilepsy (
Publicado em: 2009
-
12. Agressividade defensiva: efeitos do tratamento neonatal com sertralina
O sistema serotoninÃrgico tem importÃncia no desenvolvimento e no controle de vÃrias funÃÃes do sistema nervoso central. O uso de fÃrmacos no perÃodo neonatal induz alteraÃÃes morfofisiolÃgica e comportamental. As drogas serotoninÃrgicas tÃm sido bastante utilizadas para depressÃo, ansiedade e em crianÃas, muitas vezes, menores de 5 anos com o
Publicado em: 2007