Nerve Growth Factors
Mostrando 1-12 de 165 artigos, teses e dissertações.
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1. Effect of dihydroferulic acid obtained from fermented rice bran extract on neuroprotection and behavioral recovery in an ischemic rat model
Abstract This study aimed to evaluate whether dihydroferulic acid (dFA) promoted the viability of H2O2-treated PC12 cells and functional recovery from ischemic injury. The animals were divided into four groups for the study: (1) the vehicle treated (saline, 1 mL/kg), (2) dFA 5 mg/kg treated, (3) dFA10 mg/kg treated, and (4) dFA 20 mg/kg treated groups. Neuro
Food Sci. Technol. Publicado em: 2020-12
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2. Hypericum perforatum chronic treatment affects cognitive parameters and brain neurotrophic factor levels
Objective: To evaluate the effects of Hypericum perforatum (hypericum) on cognitive behavior and neurotrophic factor levels in the brain of male and female rats. Methods: Male and female Wistar rats were treated with hypericum or water during 28 days by gavage. The animals were then subjected to the open-field test, novel object recognition and step-down i
Rev. Bras. Psiquiatr.. Publicado em: 09/08/2018
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3. Effects of cognitive-behavioral therapy on neurotrophic factors in patients with major depressive disorder
Objective: To correlate neurotrophic factors – brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), and beta-nerve growth factor (beta-NGF) – and severity of depressive symptoms in patients diagnosed with major depressive disorder (MDD) undergoing cognitive-behavioral therapy (CBT). Methods: In this quasi-experi
Rev. Bras. Psiquiatr.. Publicado em: 11/06/2018
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4. Serum levels of neurotrophic factors in active toxoplasmic retinochoroiditis
Abstract Toxoplasmic retinochoroiditis (TR) is the most common identifiable cause of posterior uveitis in Brazil. Response to treatment and clinical presentation may vary significantly. We assessed serum levels of brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), neurotrophin (NT)-3, and
Braz J Infect Dis. Publicado em: 2017-03
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5. The brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism affects memory performance in older adults
Objective: Memory impairment is an important contributor to the reduction in quality of life experienced by older adults, and genetic risk factors seem to contribute to variance in age-related cognitive decline. Brain-derived neurotrophic factor (BDNF) is an important nerve growth factor linked with development and neural plasticity. The Val66Met polymorphi
Rev. Bras. Psiquiatr.. Publicado em: 12/01/2017
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6. Efeito do plasma rico em plaquetas e da eritropoietina na regeneração do nervo ciático de ratos wistar
Injuries to the peripheral nervous system present a challenge for regenerative medicine. The study investigated the effects of platelet-rich plasma (PRP) and erythropoietin (EPO), alone or in combination, in the regeneration of peripheral nerve in rats. The work was developed in three phases using 70 rats. The first phase, evaluated the platelet concentratio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/08/2012
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7. Serum levels of brain-derived neurotrophic factor and thiobarbituric acid reactive substances in chronically medicated schizophrenic patients : a positive correlation / Níveis séricos do fator neurotrófico derivado do cérebro e dos produtos de reação com o ácido tiobarbitúrico em pacientes com esquizofrenia cronicamente medicados : correlação positiva
Objetivo: As neurotrofinas, enzimas antioxidantes e marcadores de oxidação têm interações. Este estudo verificou se existem correlações entre os níveis séricos de superóxido-dismutase, uma enzima chave na defesa antioxidante, os produtos de reação com o ácido tiobarbitúrico, um indicador direto de peroxidação lipídica, e o fator neurotrófic
Publicado em: 2011
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8. Functional and histological analysis of the neurotrophin-4 on medullar injury of rats / Análise funcional e histológica da ação da neurotropina-4 sobre a lesão medular em ratos
As pesquisas em lesão medular tiveram um avanço significativo nas últimas duas décadas. Várias substâncias têm sido testadas, dentre elas, os fatores neurotróficos que são proteínas que auxiliam na maturação e desenvolvimento do sistema nervoso. O objetivo deste estudo foi conduzir testes que propiciem a análise dos efeitos da recuperação func
Publicado em: 2008
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9. Avaliação clinica e histopatologica de tumores da glandula parotida / Clinical and histopathological analysis of parotid gland tumors
Salivary gland tumors are rare, with an annual incidence of about 0,4 to 13,5 cases per 100000 people. Most of the cases affect the parotid gland, representing 64% to 80% of the cases and the majority is benign. The aim of this study was to analyze the main clinical and histopathological features of parotid gland tumors. We select all the patients with prima
Publicado em: 2008
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10. TNF and NGF involvement in the nerve damage of leprosy. / Envolvimento do TNF e do NGF na lesão neural da hanseníase.
O dano nervoso, característico da hanseníase, é causa de deformidade nos pacientes e está diretamente relacionado à invasão das células de Schwann (CS) pelo Mycobacterium leprae (M. leprae). Já foi descrito que o sítio de lesão do nervo é rico em mediadores extracelulares incluindo citocinas, fatores de crescimento e proteases sendo altamente regu
Publicado em: 2008
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11. Neurotrophic factors and neurologic disease.
Discovered only 40 years ago, nerve growth factor is the prototypic neurotrophic factor. By binding to specific receptors on certain neurons in the peripheral nervous system and brain, nerve growth factor acts to enhance their survival, differentiation, and maintenance. In recent years, many additional neurotrophic factors have been discovered; some are stru
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12. Chromatin binding of epidermal growth factor, nerve growth factor, and platelet-derived growth factor in cells bearing the appropriate surface receptors.
We analyzed the uptake and intracellular distribution of 125I-labeled epidermal growth factor, nerve growth factor, and platelet-derived growth factor in different cell lines that express or do not express the respective surface receptors for these factors. After 1 hr of incubation, all three growth factors were detected in the cytoplasmic fraction and in th