Nnos
Mostrando 1-12 de 115 artigos, teses e dissertações.
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1. Picroside II attenuates ischemia/reperfusion testicular injury by alleviating oxidative stress and apoptosis through reducing nitric oxide synthesis
Abstract Purpose: To investigate the effect of Picroside II on testicular ischemia and reperfusion (l/R) injury and the underlying mechanism. Methods: Sprague-Dawley rats were randomly divided into 4 groups: sham operated group (Sham), Sham with Picroside II treatment group (Sham+ Pic II), l/R group (l/R) and l/R with Picroside II treatment group (I/R+ Pic
Acta Cir. Bras.. Publicado em: 20/12/2019
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2. Aerobic exercise repairs neurological function after cerebral ischaemia by regulating the nitric oxide
Abstract: To investigate the mechanism of different exercise patterns on neurological function after focal cerebral ischaemia in rats. Rats with focal cerebral cerebral ischaemia were randomly divided into an aerobic exercise group, an exhaustive exercise group and a control group, with 8 rats in each group. A score for nerve function in each group was calcu
An. Acad. Bras. Ciênc.. Publicado em: 09/09/2019
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3. DOES THE RHEUMATOID ARTHRITIS AFFECT THE ENTERIC NERVOUS SYSTEM?
RESUMO CONTEXTO: Poucos estudos sobre doenças artríticas têm sido realizados para verificar a presença de neurodegeneração. Diante do aumento do estresse oxidativo e dos efeitos extra-articulares da artrite reumatoide, estudos gastrointestinais devem ser investigados visando uma melhor compreensão dos efeitos sistêmicos da doença no sistema nervos
Arq. Gastroenterol.. Publicado em: 26/08/2019
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4. Penile alterations at early stage of type 1 diabetes in rats
ABSTRACT Objective Diabetes affects the erectile function significantly. However, the penile alterations in the early stage of diabetes in experimental animal models have not been well studied. We examined the changes of the penis and its main erectile components in diabetic rats. Materials and methods Male Sprague-Dawley rats were divided into 2 groups:
Int. braz j urol.. Publicado em: 2017-08
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5. Effect of S-methyl-l-thiocitrulline dihydrochloride on rat micturition reflex
ABSTRACT Objective: To evaluate the effect of neuronal nitric oxide synthase on the striated urethral sphincter and the urinary bladder. Materials and Methods: A coaxial catheter was implanted in the proximal urethra and another one in the bladder of female rats, which were anesthetized with subcutaneous injection of urethane. The urethral pressure with sa
Int. braz j urol.. Publicado em: 2016-10
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6. Improvement of erectile dysfunction by the active pepide from Urechis unicinctus by high temperature/pressure and ultra - wave assisted lysis in Streptozotocin Induced Diabetic Rats
ABSTRACT Introduction: We investigate the effect of active peptide from Urechis unicinctus (UU) by high temperature/pressure and ultra-wave assisted lysis on erectile dysfunction in streptozotocin-induced diabetic rats. Materials and Methods: Forty 12-week-old Sprague-Dawley rats were used in this study. Diabetes was induced by a one-time intraperitoneal i
Int. braz j urol.. Publicado em: 2016-08
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7. Combination vitamin C and vitamin E prevents enteric diabetic neuropathy in the small intestine in rats
The present study evaluated the effects of supplementation with a combination of vitamin C and vitamin E on NADH-diaphorase-positive (NADH-d+) and neuronal nitric oxide synthase (nNOS)-immunoreactive myenteric neurons in the duodenum and ileum in diabetic rats. Forty rats were distributed into the following groups: normoglycemic (N), normoglycemic supplement
Braz. arch. biol. technol.. Publicado em: 01/05/2015
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8. Administração hipotalâmica aguda de L-arginina aumenta a ingestão alimentar em ratos
Objetivo: Este estudo investigou os efeitos da suplementação crônica (oral) e aguda (infusão no hipotálamo) com L-arginina sobre a saciedade, composição corporal e mudanças comportamentais em ratos. Métodos: Vinte ratos foram divididos em dois grupos e tratados por via oral durante 60 dias; um grupo recebeu uma dose de L-arginina (1 g/kg de peso co
Rev. Nutr.. Publicado em: 2015-02
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9. Estudo da associação de polimorfismos genéticos da sintase induzida do óxido nítrico (inos) com migrânea = : Inducible nitric oxide synthase haplotype associated with migraine and aura / Inducible nitric oxide synthase haplotype associated with migraine and aura
A migrânea é uma cefaléia primária episódica com incidência mundial de 10% e alto impacto socioeconômico, afetando predominantemente as mulheres. Em 30% dos casos, as crises de migrânea são acompanhadas por sintomas neurológicos focais que caracterizam o fenômeno da aura. A fisiopatologia da migrânea continua sob investigação. Todavia, acredita
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/08/2012
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10. Consequences of hyperhomocysteinemia on the response to endothelin-1 and phenylephrine in rats corpus cavernosum / Consequências da hiperhomocisteinemia sobre a resposta à endotelina-1 e fenilefrina em corpo cavernoso de ratos
A hiperhomocisteinemia (HHcy) tem sido associada à disfunção endotelial, em decorrência do aumento de ânion superóxido (O2-) e redução da biodisponibilidade de óxido nítrico (NO), fatos estes que poderiam acarretar disfunção erétil. O objetivo deste trabalho foi estudar as consequências da HHcy sobre as respostas à endotelina-1 (ET-1) e fenile
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/02/2012
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11. Efeito da óxido nítrico sintase na dor neuropática. / Effect of Nitric Oxide Synthase in neuropathic pain.
A lesão do nervo periférico resulta em dor neuropática persistente ou crônica, caracterizada por dor espontânea em queimação, acompanhada de alodinia e hiperalgesia. A ocorrência de alterações patológicas no sistema nervoso periférico e na medula espinal contribui para o desenvolvimento da dor neuropática. Estas alterações incluem descargas ec
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/02/2012
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12. Depressed nNOS expression during spine transition in the developing hippocampus of FMR1 KO mice
Nitric oxide (NO), synthesized as needed by NO synthase (NOS), is involved in spinogenesis and synaptogenesis. Immature spine morphology is characteristic of fragile X syndrome (FXS). The objective of this research was to investigate and compare changes of postnatal neuronal NOS (nNOS) expression in the hippocampus of male fragile X mental retardation 1 gene
Braz J Med Biol Res. Publicado em: 2012-12