Non Genomic Actions
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Neural regulation of the stress response: glucocorticoid feedback mechanisms
The mammalian stress response is an integrated physiological and psychological reaction to real or perceived adversity. Glucocorticoids are an important component of this response, acting to redistribute energy resources to both optimize survival in the face of challenge and to restore homeostasis after the immediate challenge has subsided. Release of glucoc
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-04
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2. Non genomic actions of triiodothyronine (T3) on the expression polyadenylation and distribution of TSH granules in thyrotrophs of hypothyroid rats / Ações não genômicas da triiodotironina (T3) sobre a expressão, poliadenilação e distribuição dos grânulos de TSH nos tireotrofos de ratos hipotireiodeos
The thyroid-stimulating hormone (TSH) is the main regulator of the synthesis and secretion of thyroid hormones (TH), which exert a negative feedback mechanism in the pituitary by reducing the synthesis of β and α (CGA - Glycoprotein hormones alpha chain) chains through mechanisms that involve changes in the tra
Publicado em: 2010
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3. Revisiting steroid treatment for septic shock: molecular actions and clinical effects - a review
Corticosteroids are widely used to treat a diversity of pathological conditions including allergic, autoimmune and some infectious diseases. These drugs have complex mechanisms of action involving both genomic and non-genomic mechanisms and interfere with different signal transduction pathways in the cell. The use of corticosteroids to treat critically ill p
Memórias do Instituto Oswaldo Cruz. Publicado em: 2009-07
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4. Effects of estrogen on the vascular system
The cardiovascular protective actions of estrogen are partially mediated by a direct effect on the vessel wall. Estrogen is active both on vascular smooth muscle and endothelial cells where functionally competent estrogen receptors have been identified. Estrogen administration promotes vasodilation in humans and in experimental animals, in part by stimulatin
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-09
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5. Non-genomic mechanism of 17 beta-oestradiol-induced inhibition of contraction in mammalian vascular smooth muscle.
17 beta-Oestradiol (E2) at 0.1-10 microM directly inhibited various tonic and phasic smooth muscle contractions. The mechanism(s) of oestrogen-induced inhibition of contraction was studied using intact and permeabilized strips and isolated single cells of smooth muscle. 2. In endothelium-denuded vascular smooth muscle, E2 attenuated high K(+)-induced force d
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6. Tracking the estrogen receptor in neurons: Implications for estrogen-induced synapse formation
Estrogens (E) and progestins regulate synaptogenesis in the CA1 region of the dorsal hippocampus during the estrous cycle of the female rat, and the functional consequences include changes in neurotransmission and memory. Synapse formation has been demonstrated by using the Golgi technique, dye filling of cells, electron microscopy, and radioimmunocytochemis
The National Academy of Sciences.