Notch 3
Mostrando 1-12 de 143 artigos, teses e dissertações.
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1. Possible association between a polymorphism of EPAS1 gene and persistent pulmonary hypertension of the newborn: a case-control study
Abstract Objective: To explore possible genes related to the development of persistent pulmonary hypertension of the newborn (PPHN). Methods: The authors identified 285 single nucleotide polymorphisms (SNPs) of 11 candidate genes (BMPR2, EPAS1, PDE3A, VEGFA, ENG, NOTCH3, SOD3, CPS1, ABCA3, ACVRL1, and SMAD9), using an Illumina Asian Screening Array-24 v1.0
Jornal de Pediatria. Publicado em: 2022
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2. Association between Chagas disease and changes in the optic nerve and retinal nerve fiber layer
RESUMO Objetivo: Testar a hipótese de que a doença de Chagas predispõe a alterações no nervo óptico e camada de fibras nervosas peripapilar. Métodos: Foi realizado um estudo transversal com 41 pacientes diagnosticados com doença de Chagas e 41 controles, pareados por sexo e idade. Os pacientes foram submetidos a exames oftalmológicos, incluindo me
Arq. Bras. Oftalmol.. Publicado em: 21/02/2019
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3. HtrA1 suppresses the growth of pancreatic cancer cells by modulating Notch-1 expression
Pancreatic cancer is well known to be the most deadly malignancy with the worst survival rate of all cancers. High temperature requirement factor A1 (HtrA1) plays an important role in cancer cell proliferation, migration, apoptosis, and differentiation. This study aimed to explore the function of HtrA1 in pancreatic cancer cell growth and its underlying mech
Braz J Med Biol Res. Publicado em: 23/11/2018
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4. MicroRNA-221 promotes cell proliferation, migration, and differentiation by regulation of ZFPM2 in osteoblasts
Bone fracture is a common medical condition, which may occur due to traumatic injury or disease-related conditions. Evidence suggests that microRNAs (miRNAs) can regulate osteoblast differentiation and function. In this study, we explored the effects and mechanism of miR-221 on the growth and migration of osteoblasts using MC3T3-E1 cells. The expression leve
Braz J Med Biol Res. Publicado em: 18/10/2018
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5. Designing Four Notched Bands Microstrip Antenna for UWB Applications, Assessed by Analytic Hierarchy Process Method
Abstract In this study, a novel microstrip fed Ultra Wideband (UWB) antenna is presented. The proposed antenna, with a size of 26×30×1.6mm3, is capable of removing four bands of interference in the coverage band. Firs, three filtered bands are created by cutting U, L, and C-shapes, a horizontal line on the patch, and fed line of antenna. The fourth notch i
J. Microw. Optoelectron. Electromagn. Appl.. Publicado em: 2017-09
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6. Tangeretin has anti-asthmatic effects via regulating PI3K and Notch signaling and modulating Th1/Th2/Th17 cytokine balance in neonatal asthmatic mice
Asthma is a chronic allergic disease characterized by airway inflammation, airway hyper-responsiveness (AHR), and mucus hypersecretion. T-lymphocytes are involved in the pathogenesis of asthma, mediating airway inflammatory reactions by secreting cytokines. The phosphoinositide 3-kinase (PI3K) and Notch signaling pathways are associated with T cell signaling
Braz J Med Biol Res. Publicado em: 20/07/2017
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7. Reduced placental volume and flow in severe growth restricted fetuses
OBJECTIVES: To evaluate placental volume and vascular indices in pregnancies with severe fetal growth restriction and determine their correlations to normal reference ranges and Doppler velocimetry results of uterine and umbilical arteries. METHODS: Twenty-seven fetuses with estimated weights below the 3rd percentile for gestational age were evaluated. Pla
Clinics. Publicado em: 2016-06
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8. CADASIL: DIAGNÓSTICO GENÉTICO E ULTRAESTRUTURAL. RELATO DE CASO
ABSTRACT Arteriopatia Cerebral Autossômica Dominante com Infartos Subcorticais e Leucoencefalopatia (CADASIL) é uma desordem hereditária que acomete a vasculatura cerebral devido a mutações no gene do NOTCH 3. O diagnóstico pode ser estabelecido através de testes genéticos para a detecção das mutações e/ou de biópsia de pele. É relatado um caso
Dement. neuropsychol.. Publicado em: 2015-12
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9. Expression analysis of Notch signaling pathway molecules in SHED cultured in keratinocyte growth medium
Aim: To detect the expression of molecules associated with Notch signaling pathway in stem cells from human exfoliated deciduous teeth (SHED) cultured in specific differentiation medium, namely, keratinocyte growth medium (KGM).
Methods: RNA was extracted from SHED harvested on day 1, 3 and 7. RNA was reve
Braz. J. Oral Sci.. Publicado em: 2015-06
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10. On the Processing and Properties of Clay/Polymer Nanocomposites CPNC
AbstractAn experimental investigation followed by fundamental characterization and discussion on the effect of nanoclay filler on the mechanical and fracture properties of polymer matrix was carried out. The study was carried out on clay/polymer nanocomposite made of High Density polyethylene (HDPE M40060) produced by Saudi Arabian company SABIC and montimor
Lat. Am. j. solids struct.. Publicado em: 2015-04
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11. Transcriptional profile of fibroblasts obtained from the primary site, lymph node and bone marrow of breast cancer patients
Cancer-associated fibroblasts (CAF) influence tumor development at primary as well as in metastatic sites, but there have been no direct comparisons of the transcriptional profiles of stromal cells from different tumor sites. In this study, we used customized cDNA microarrays to compare the gene expression profile of stromal cells from primary tumor (CAF, n
Genet. Mol. Biol.. Publicado em: 2014-09
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12. Rectangular notch loaded dual band annular ring patch antenna
In this article, a dual band annular ring patch antenna is theoretically investigated using the equivalent circuit concept.Two symmetrical rectangular notches are etched in radiating ring patch with respect to feed point. It is observed that the resonant frequency is directly proportional to the notch width and notch length. The bandwidth of the antenna at l
J. Microw. Optoelectron. Electromagn. Appl.. Publicado em: 2014-06