Nucleus Accumbens
Mostrando 1-12 de 122 artigos, teses e dissertações.
-
1. A narrative review on invasive brain stimulation for treatment-resistant depression
While most patients with depression respond to pharmacotherapy and psychotherapy, about one-third will present treatment resistance to these interventions. For patients with treatment-resistant depression (TRD), invasive neurostimulation therapies such as vagus nerve stimulation, deep brain stimulation, and epidural cortical stimulation may be considered. We
Brazilian Journal of Psychiatry. Publicado em: 2022
-
2. Reinforcement omission effects in rats with bilateral lesions in the substantia nigra pars compacta and ventral tegmental area
Reinforcement omission effects (ROEs) are characterized by higher response rates after reinforcement omission than after reinforcement delivery. This pattern of behavior is interpreted in terms of motivational and attentional processes. Recent studies from our laboratory have shown that the amygdala, nucleus accumbens, and medial prefrontal cortex are involv
Braz J Med Biol Res. Publicado em: 10/07/2019
-
3. Tryptophan overloading activates brain regions involved with cognition, mood and anxiety
ABSTRACT Tryptophan is the only precursor of serotonin and mediates serotonergic activity in the brain. Previous studies have shown that the administration of tryptophan or tryptophan depletion significantly alters cognition, mood and anxiety. Nevertheless, the neurobiological alterations that follow these changes have not yet been fully investigated. The ai
An. Acad. Bras. Ciênc.. Publicado em: 16/02/2017
-
4. Astrocytic expression of GFAP and serum levels of IL-1β and TNF-α in rats treated with different pain relievers
ABSTRACT Pro-inflammatory cytokines and glial cells, especially microglial cells, have been implicated in persistent pain sensitization. Less is known about the role of astrocytes in pain regulation. This study aimed to observe the expression of the astrocytic biomarker glial fibrillary acidic protein (GFAP) and the serum levels of interleukin 1 beta (IL-1β
Braz. J. Pharm. Sci.. Publicado em: 2016-12
-
5. New-onset panic attacks after deep brain stimulation of the nucleus accumbens in a patient with refractory obsessive-compulsive and bipolar disorders: a case report
Rev. Bras. Psiquiatr.. Publicado em: 2015-06
-
6. Effect of postnatal intermittent hypoxia on locomotor activity and neuronal development in rats tested in early adulthood
The present study evaluated the effects of postnatal intermittent hypoxia on locomotor activity and neuronal cell survival in early adulthood rats. During a critical period of brain development on postnatal day (PD) 7-11, male rat pups were exposed to intermittent hypoxia and randomly assigned to three experimental groups: (1) intermittent hypoxia, (2) normo
Psychol. Neurosci.. Publicado em: 27/05/2014
-
7. Open field behavior and intra-nucleus accumbens dopamine release in vivo in virgin and lactating rats
In adult female mammals, reproductive experience (e.g., mating, pregnancy, parturition, and lactation) has long-term behavioral, endocrine, and neurochemical implications. This experience causes behavioral and neurochemical changes that involve several brain areas important for the expression of maternal behavior. The present study showed that lactating rats
Psychology & Neuroscience. Publicado em: 2011-06
-
8. Learning processes and the neural analysis of conditioning
Classical and operant conditioning principles, such as the behavioral discrepancy-derived assumption that reinforcement always selects antecedent stimulus and response relations, have been studied at the neural level, mainly by observing the strengthening of neuronal responses or synaptic connections. A review of the literature on the neural basis of behavio
Psychology & Neuroscience. Publicado em: 2010-12
-
9. Estudo das aferências imunorreativas ao hormônio concentrador de melanina (MCH) do núcleo accumbens, no rato Long-Evans (Rattus norvegicus). / Study of melanin-concentrating hormone (MCH) immunoreactive inputs of nucleus acumbens, in rats Long-Evans (Rattus norvegicus) .
O MCH é um neuropeptídeo sintetizado preferencialmente no hipotálamo que exibe projeções para todo o neuroeixo, podendo modular vários processos fisiológicos, como a ingestão aguda de alimento. Um alvo de suas projeções é o núcleo accumbens (Acb), componente do estriado ventral envolvido na recompensa de estímulos hedônicos. Nossa contribuiçã
Publicado em: 2010
-
10. Organization of the ventral tegmental area projections to the VTA-nigral complex and to the hypothalamus in the rat and VTA neurons projecting to the accumbens express insulin receptor substrates. / Organização das projeções da área tegmental ventral para o complexo VTA-substância negra e para o hipotálamo no rato e estudo da expressão dos substratos do receptor de insulina em neurônios da VTA que se projetam para o estriado
Numa primeira etapa, estudamos as conexões da VTA para o complexo VTA-substância negra (SN) utilizando a leucoaglutinina do Phaseolus vulgaris (PHA-L). Estas conexões são substanciais, topograficamente organizadas, com destaque para o pólo caudal da VTA que inerva bilateralmente toda a extensão deste complexo. Numa segunda etapa, estudamos as projeçõ
Publicado em: 2010
-
11. Caracterização experimental do fenômeno de sensibilização comportamental imediata‟ após administração única de diferentes drogas de abuso em camundongos. / Experimental characterization of the phenomenon of awarenessbehavioral "immediately" after a single administration of different drugs of abuse in mice.
The behavioral sensitization phenomenon is characterized by a progressive and enduring enhancement of the locomotor stimulant effect of drugs of abuse following repeated treatment in rodents. This behavioral phenomenon seems to share the same neurobiological basis of drug dependence in humans and has been proposed as a pathophysiological animal model of drug
Publicado em: 2009
-
12. Sensibilização cruzada entre anfetamina e nicotina: avaliação neuroquímica do núcleo acumbens e córtex préfrontal em ratos adolescentes e adultos
Uma característica comum das substâncias que causam dependência é o aumento gradual e progressivo da atividade locomotora observado após a administração repetida, esse fenômeno é denominado sensibilização comportamental. A sensibilização comportamental resulta de adaptações neuroquímicas e moleculares do sistema dopaminérgico mesocorticolím
Publicado em: 2009