Olfactory Receptor
Mostrando 1-12 de 211 artigos, teses e dissertações.
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1. Extrapulmonary manifestations of COVID-19 in children: a comprehensive review and pathophysiological considerations
ABSTRACT Objective: The aim of this review was to summarize the most common extrapulmonary manifestations in pediatric patients with COVID-19, as well as to discuss clinical, epidemiological, and pathophysiological aspects of these clinical presentations in children. Source of data: An extensive search of literature was performed in order to identify pedia
J. Pediatr. (Rio J.). Publicado em: 2021-04
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2. História social e autoritarismo no Brasil: ligações entre passado e presente
ABSTRACT Objective: The aim of this review was to summarize the most common extrapulmonary manifestations in pediatric patients with COVID-19, as well as to discuss clinical, epidemiological, and pathophysiological aspects of these clinical presentations in children. Source of data: An extensive search of literature was performed in order to identify pedia
Estud. av.. Publicado em: 2021-04
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3. Expression and Localization of Olfactory Receptor AcerOr1 from Chinese Honey Bee, Apis cerana cerana (Hymenoptera, Apidae)
ABSTRACT Olfactory receptors are essential for recognition and detection of odor in honeybees. Although we have cloned and characterized the sequence of olfactory receptor AcerOr1 before, the tissue distribution and location of this gene in the nurse and the forager worker Apis cerana cerana were not very clear. To further investigate this information of Ace
Braz. arch. biol. technol.. Publicado em: 29/11/2018
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4. Mutações inativadoras dos genes PROK2 e PROKR2 em pacientes com hipogonadismo hipogonadotrófico isolado / PROK2 and PROKR2 inactivating mutations in patients with idiopathic hypogonadotropic hypogonadism
O sistema da procineticina desempenha um papel importante na migração dos neurônios secretores de GnRH e na neurogênese do bulbo olfatório. Camundongos com ablação dos genes que codificam a procineticina 2 (PROK2) e seu receptor (PROKR2) apresentaram fenótipos semelhantes ao da síndrome de Kallmann descrita em humanos. Mutações inativadoras nos ge
Publicado em: 2011
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5. Análise das regiões promotoras dos genes de receptores olfatórios e de receptores de feromônios do tipo 1 / Analysis of promoter regions of the olfactory and type 1 vomeronasal receptor genes
In the mouse genome there are approximately 1000 genes that encode olfactory receptors (ORs) and 150 genes that encode type 1 vomeronasal receptors (V1Rs) dispersed in various chromosomes. Each olfactory or vomeronasal neuron selects one single allele from one single receptor gene (OR or V1R) for expression while the rest of the repertoire remains silenced.
Publicado em: 2008
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6. RIC-8B, a putative GEF of the olfactory system, interacts with Gαolf, Gβ1 e Gγ13 / Ric-8B, uma GEF putativa do sistema olfatório, interage com Gαolf, Gβ1 e Gγ13
The mammalian olfactory system detects small amounts of thousands of different chemical compounds. Odorant perception starts when an odorant in the air binds to an olfactory receptor (OR). ORs belong to the super family of G-protein coupled receptors (GPCRs). Even though the odorant signaling pathway is well known, little is known about its modulators. In 20
Publicado em: 2008
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7. Uso de técnicas computacionais no estudo da transcrição e regulação gênica em Homo sapiens e Mus musculus / Use of computational methods to study the transcription and gene regulation in Homo sapiens and Mus musculus
Genes, nucleotide sequences necessary for the synthesis of functional molecules, are transcribed and regulated by extremely complex cellular and molecular processes. To understand when and in which tissues the genes are expressed, their functional isoforms, control regions and the factors involved in gene regulation is one of major challenges of modern molec
Publicado em: 2008
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8. Functional identification and reconstitution of an odorant receptor in single olfactory neurons
The olfactory system is remarkable in its capacity to discriminate a wide range of odorants through a series of transduction events initiated in olfactory receptor neurons. Each olfactory neuron is expected to express only a single odorant receptor gene that belongs to the G protein coupled receptor family. The ligand–receptor interaction, however, has not
The National Academy of Sciences.
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9. Specific olfactory receptor populations projecting to identified glomeruli in the rat olfactory bulb.
A critical gap exists in our knowledge of the topographical relationship between the olfactory epithelium and olfactory bulb. The present report describes the application to this problem of a method involving horseradish peroxidase conjugated to wheat germ agglutinin. This material was iontophoretically delivered to circumscribed glomeruli in the olfactory b
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10. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels
Previous computational analyses have identified approximately 1,500 mouse olfactory receptors, but experimental evidence confirming olfactory function is available for very few receptors. A mouse olfactory epithelium cDNA library was screened to obtain olfactory receptor expressed sequence tags, providing evidence of olfactory function for many additional ol
BioMed Central.
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11. Organization and expression of canine olfactory receptor genes.
Four members of the canine olfactory receptor gene family were characterized. The predicted proteins shared 40-64% identity with previously identified olfactory receptors. The four subfamilies identified in Southern hybridization experiments had as few as 2 and as many as 20 members. All four genes were expressed exclusively in olfactory epithelium. Expressi
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12. Nested expression domains for odorant receptors in zebrafish olfactory epithelium
The mapping of high-dimensional olfactory stimuli onto the two-dimensional surface of the nasal sensory epithelium constitutes the first step in the neuronal encoding of olfactory input. We have used zebrafish as a model system to analyze the spatial distribution of odorant receptor molecules in the olfactory epithelium by quantitative in situ hybridiza
The National Academy of Sciences of the USA.