Osteogenic Response
Mostrando 1-12 de 17 artigos, teses e dissertações.
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1. Stanozolol promotes osteogenic gene expression and apposition of bone mineral in vitro
Abstract Stanozolol (ST) is a synthetic androgen with high anabolic potential. Although it is known that androgens play a positive role in bone metabolism, ST action on bone cells has not been sufficiently tested to support its clinical use for bone augmentation procedures. Objective: This study aimed to assess the effects of ST on osteogenic activity and ge
J. Appl. Oral Sci.. Publicado em: 08/11/2018
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2. Oral implant osseointegration model in C57Bl/6 mice: microtomographic, histological, histomorphometric and molecular characterization
Abstract Despite the successful clinical application of titanium (Ti) as a biomaterial, the exact cellular and molecular mechanisms responsible for Ti osseointegration remains unclear, especially because of the limited methodological tools available in this field. Objective: In this study, we present a microscopic and molecular characterization of an oral i
J. Appl. Oral Sci.. Publicado em: 11/06/2018
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3. Effects of Syzygium aromaticum, Cinnamomum zeylanicum, and Salvia triloba extracts on proliferation and differentiation of dental pulp stem cells
Abstract Hypersensitivity, local irritative and cytotoxic effects are known for the chemical components of Syzygium aromaticum and Cinnamomum zeylanicum contained in dental materials. However, there is no intimate data in dentistry using the whole extracts of these plants and introducing new ones. Salvia triloba is a well-known anti-inflammatory plant that c
J. Appl. Oral Sci.. Publicado em: 2017-10
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4. Thymbra Spicata Var. Intricata Induces Mesenchymal Stem Cell Proliferation and Osteogenic Differentiation
ABSTRACT A natural agent that maintains mesenchymal stem cell (MSCs) viability, promotes osteogenic differentiation while modulating the immunological response could achieve success in regeneration during healing and may also prevent bone resorption and improve regeneration. We aimed to demonstrate that a Thymbra spicata var. intricata extract could induce p
Braz. arch. biol. technol.. Publicado em: 17/08/2017
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5. Low-level laser therapy associated to a resistance training protocol on bone tissue in diabetic rats
ABSTRACT Objective The present study aimed to evaluate the in vivo response of a resistance training and low-level laser therapy (LLLT) on tibias and femurs of rats with diabetes mellitus (DM). Materials and methods Forty male Wistar rats were randomly distributed into four experimental groups: control group (CG), diabetic group (DG), diabetic trained gr
Arch. Endocrinol. Metab.. Publicado em: 25/08/2016
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6. CTLA4 enhances the osteogenic differentiation of allogeneic human mesenchymal stem cells in a model of immune activation
Allogeneic mesenchymal stem cells (allo-MSCs) have recently garnered increasing interest for their broad clinical therapy applications. Despite this, many studies have shown that allo-MSCs are associated with a high rate of graft rejection unless immunosuppressive therapy is administered to control allo-immune responses. Cytotoxic T-lymphocyte-associated pro
Braz J Med Biol Res. Publicado em: 19/05/2015
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7. Efeitos da suplementação de zinco e do treinamento físico sobre o metabolismo e a densidade óssea de ratas ovariectomizadas
Osteoporosis is a serious public health problem, and increasingly is recognized as a disease limiting quality of life, especially for the elderly. The role of zinc in human nutrition has been extensively studied. Several hormones and zinc-dependent enzymes are involved in bone metabolism. Physical activity has been advocated as a means to increase and mainta
Publicado em: 2010
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8. COMPARISON OF BONE MINERAL DENSITY OF MALE ATHLETES AND PRACTITIONERS OF DIFFERENTS SPORTS ACTIVITIES / COMPARAÇÃO DA DENSIDADE MINERAL ÓSSEA DE ATLETAS DO SEXO MASCULINO PRATICANTES DE DIFERENTES MODALIDADES ESPORTIVAS
O objetivo desse estudo foi verificar e comparar a Densidade Mineral Óssea (DMO): total e regional (pernas, coluna, pelve e braços) de atletas de quatro modalidades esportivas: voleibol (AV), futebol de campo (AF), natação (AN) e ciclismo (AC) e, um grupo controle (GC). A amostra deste estudo foi selecionada convenientemente, foi composta por 51 sujeitos
Publicado em: 2010
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9. Bone regeneration after demineralized bone matrix and castor oil (Ricinus communis) polyurethane implantation
Innocuous biocompatible materials have been searched to repair or reconstruct bone defects. Their goal is to restore the function of live or dead tissues. This study compared connective tissue and bone reaction when exposed to demineralized bovine bone matrix and a polyurethane resin derived from castor bean (Ricinus communis). Forty-five rats were assigned
Journal of Applied Oral Science. Publicado em: 2008-04
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10. Estrogen suppresses activation but enhances formation phase of osteogenic response to mechanical stimulation in rat bone.
We used a model whereby mechanical stimulation induces bone formation in rat caudal vertebrae, to test the effect of estrogen on this osteogenic response. Unexpectedly, estrogen administered daily throughout the experiments (8-11 d) suppressed, and ovariectomy enhanced, mechanically induced osteogenesis. Osteogenesis was unaffected by the resorption-inhibito
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11. Histone H4-related osteogenic growth peptide (OGP): a novel circulating stimulator of osteoblastic activity.
It has been established that regenerating marrow induces an osteogenic response in distant skeletal sites and that this activity is mediated by factors released into the circulation by the healing tissue. In the present study we have characterized one of these factors, a 14 amino acid peptide named osteogenic growth peptide (OGP). Synthetic OGP, identical in
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12. Stimulation of the expression of osteogenic and chondrogenic phenotypes in vitro by osteogenin.
Osteogenin was recently purified and the amino acid sequences of tryptic peptides were determined. Osteogenin in conjunction with insoluble collagenous bone matrix induces cartilage and bone formation in vivo. To understand the mechanism of action of osteogenin, we examined its influence on periosteal cells, osteoblasts, fibroblasts, chondrocytes, and bone m