Ovcar 3
Mostrando 1-12 de 42 artigos, teses e dissertações.
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1. Essential Oils Obtained from Aerial Eugenia punicifolia Parts: Chemical Composition and Antiproliferative Potential Evidenced through Cell Cycle Arrest
Essential oils (EOs) of the leaves of three Eugenia punicifolia specimens from two different Reservation Parks, namely Parque Nacional das Nascentes do Rio Parnaíba (EpNRP-I and EpNRP-II) and Parque Nacional da Chapada das Mesas (EpCM), in the state of Maranhão, Brazil, were extracted by hydrodistillation and investigated by gas chromatography coupled to m
J. Braz. Chem. Soc.. Publicado em: 2021-07
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2. Antiproliferative Effect of Urera baccifera Leaves Against Ovarian Carcinoma Cell Line (OVCAR-3)
Abstract Natural products, especially phytochemicals, have been extensively studies and have exhibited important antiproliferative effects. The American native species Urera baccifera (L.) Gaudich. ex Wedd. (Urticaceae) is widely distributed in Brazil, where it is known as urtiga-vermelha or urtigão. The leaves are popularly used as anti-inflammatory, antir
Braz. arch. biol. technol.. Publicado em: 24/10/2019
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3. Triagem fitoquimico e atividade antibacteriana, antifúngica, antioxidante e antitumoral in vitro da propólis vermelha de Alagoas
Resumo O trabalho teve como objetivo avaliar a atividade antimicrobiana, antioxidante, a toxicidade e a prospecção fitoquímica da Própolis Vermelha de Alagoas. A atividade antimicrobiana foi avaliada pelo método de difusão em disco. A determinação do potencial antioxidante foi realizada utilizando o método de DPPH (1,1-difenil-2-picrilhidrazil), FT
Braz. J. Biol.. Publicado em: 29/10/2018
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4. In vitro cytotoxic activity of five commercial samples of Tribulus terrestris Linn in Espírito Santo (Brazil)
ABSTRACT The objective was to investigate the total saponin and protodioscin concentrations and the cytotoxicity in vitro, of five samples of the plant Tribulus terrestris, commercially available in the metropolitan region of Vitória - Espirito Santo, Brazil, and to compare them with the aqueous extract of the plant. The chromatographic profile and quantifi
Braz. J. Pharm. Sci.. Publicado em: 09/04/2018
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5. Terpene Esters from Natural Products: Synthesis and Evaluation of Cytotoxic Activity
ABSTRACT Natural steroids and triterpenes such as b-sitosterol, stigmasterol, lupeol, ursolic and betulinic acids were transformed into its hexanoic and oleic esters, to evaluate the influence of chemical modification towards the cytotoxic activities against tumor cells. The derivatives were evaluated against five tumor cell lines [OVCAR-8 (ovarian carcinoma
An. Acad. Bras. Ciênc.. Publicado em: 14/08/2017
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6. Antiproliferative Activity of Dibenzoylmethanes from Root Bark of Muellera filipes (Benth) M.J. Silva & A.M.G. Azevedo
Three new dibenzoylmethane derivatives, (E)-3,4-methylenedioxy-2'-methoxy-2'',2''-dimethylpyrano-(5'',6'':3',4')-7-methoxychalcone, 2'-hydroxy-5'(3'''',3''''-dimethylallyl)-8-(α,α-dimethylallyl)-furano-(4'',5'':3'4')-dibenzoylmethane and 2'-O-(3'',3''-dimethylallyl)-8-(α,α-dimethylallyl)-furano-(4'',5'':3'4')-dibenzoylmethane, were isolated from a dichlo
J. Braz. Chem. Soc.. Publicado em: 2017-08
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7. New Epimeric Spirostanol and Furostanol-Type Steroidal Saponins from Cestrum laevigatum L.
Four new epimeric spirostanol and furostanol-type steroidal saponins, (25R,S)-5α-spirostan-2α,3β-diol 3-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranosyl-(1→4)-β-D-galactopyranoside, (25R,S)-5α-spirostan-2α,3β-diol 3-O-β-D-glucopyranosyl-(1→2)-α-L-rhamnopyranosyl-(1→4)-β-D-galactopyranoside, 26-O-β-D-glucopyranosyl-(25R,S)-5α-furost-20-en
J. Braz. Chem. Soc.. Publicado em: 2016-12
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8. Brown seaweed Padina gymnospora is a prominent natural wound-care product
ABSTRACT Seaweeds are related to anti-inflammatory, anti-bacterial and anti-noceptive effects. This work aimed to verify the potential of seaweed Padina gymnospora (Kützing) Sonder 1871 to improve wound healing in vitro. P. gymnospora was collected at a bethonic area in Espirito Santo. Methanolic extract of P. gymnospora was obtained by percolation. To dete
Rev. bras. farmacogn.. Publicado em: 2016-12
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9. Are salty liquid food flavorings in vitro antitumor substances?
ABSTRACT The objective of this study was to evaluate the antiproliferative, cytotoxic and genotoxic potential of salty liquid synthetic flavorings of Butter, Cheddar Cheese and Onion. The antiproliferative potential (2.9-1500 µg/mL) was assessed by MTT assay after 72h using the human tumor lines SF-295 (glioblastoma), OVCAR-8 (ovarian), HCT-116 (colon) and
An. Acad. Bras. Ciênc.. Publicado em: 2016-09
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10. Human mesenchymal stem cells are resistant to cytotoxic and genotoxic effects of cisplatin in vitro
Abstract Mesenchymal stem cells (MSCs) are known for their important properties involving multilineage differentiation potential., trophic factor secretion and localization along various organs and tissues. On the dark side, MSCs play a distinguished role in tumor microenvironments by differentiating into tumor-associated fibroblasts or supporting tumor grow
Genet. Mol. Biol.. Publicado em: 2016-03
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11. New Terpenoids from Croton limae (Euphorbiaceae)
An asymmetrical dimer of kaurane diterpene and monoterpene and four novel diterpenes were isolated from the roots of
Croton limae , along with kaempferol-3-O -glucoside, ombuin- 3-O-rutinoside and acetyl aleuritolic acid. The cytotoxic activity of the kaurane diterpene was evaluated against colorectal adenocarcinoma (HCT-11J. Braz. Chem. Soc.. Publicado em: 2015-08
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12. Chemical Composition and Cytotoxic Activity of the Root Essential Oil from Jatropha ribifolia (Pohl) Baill (Euphorbiaceae)
The essential oil of roots of Jatropha ribifolia, obtained by hydrodistillation, was characterized in terms of its chemical composition by chromatographic method with flame ionization detection (GC-FID) and gas chromatography coupled to electron ionization mass spectrometry (GC-MS). The analyses and identification pointed by mass fragmentation pattern and re
J. Braz. Chem. Soc.. Publicado em: 2015-02